Mediastinal lipomatous tumors with additional
malignant soft tissue components are exceedingly rare. Patients can have
substantially large sized tumors with long duration of symptoms and can be
misinterpreted on radiographs. Enhancing soft tissue component within a fat
density lesion within the mediastinum is alarming and should raise the
suspicion of sarcomatous component. Along with diagnostic imaging, selective CT
guided biopsy/FNAC from the enhancing soft tissue component can help in making
correct diagnosis.
References
[1]
Barbetakis, N., Samanidis, G., Samanidou, E., Kirodimos, E., Kiziridou, A., Bischiniotis, T., et al. (2007) Primary Mediastinal Liposarcoma: A Case Report. Journal of Medical Case Reports, 1, 161. http://dx.doi.org/10.1186/1752-1947-1-161
[2]
Saeed, M., Plett, S., Kim, G.E., Daldrup-Link, H. and Courtier, J. (2010) Radiological-Pathological Correlation of Pleomorphic Liposarcoma of the Anterior Mediastinum in a 17-Year-Old Girl. Pediatric Radiology, 40, S68-S70. http://dx.doi.org/10.1007/s00247-010-1797-1
[3]
Kindl, T.F., Hassan, A.M., Booth Jr., R.L., Durham, S.J. and Papadimos, T.J. (2006) A Primary High-Grade Pleomorphic Pericardial Liposarcoma Presenting as Syncope and Angina. Anesthesia & Analgesia, 102, 1363-1364. http://dx.doi.org/10.1213/01.ane.0000205753.59524.21
[4]
Plukker, J.T.M., Joosten, H.J.M., Rensing, J.B.M. and Van Haelst, U.J.G.M. (1988) Primary Liposarcoma of the Mediastinum in a Child. Journal of Surgical Oncology, 37, 257-263. http://dx.doi.org/10.1002/jso.2930370410
[5]
Wang, J.G., Wei, Z.M., Liu, H. and Li, Y.J. (2010) Primary Pleomorphic Liposarcoma of Pericardium. Interactive CardioVascular and Thoracic Surgery, 11, 325-327. http://dx.doi.org/10.1510/icvts.2010.239723
