Background: Basosquamous carcinoma (BSC) is a rare
non-melanoma skin cancer, considered to be a subtype of basal cell carcinoma
(BCC). BSC often produces distant metastases with a higher risk of recurrence
than that of BCC which is not commonly found in the lip. Case Report:A 57-year-old white female
patient presented an ulcer on her lower lip that had an ongoing development for
over six months. Physical examination, photo documentation, videoroscopy,
scraped cytology, toluidine blue test, and biopsy of the ulcer were carried
out. Results:Upon
physical examination we observed an actinic cheilitis associated with the
ulcer. Videoroscopy revealed the presence of fissures and erosion that had not been seen by oroscopy.
Toluidine blue test was only positive for the region of the ulcer. Cytological
analysis revealed rare nests compatible with carcinoma. Histopathology of the
biopsy revealed a carcinoma with nests lined by basal cells associated with
areas of squamous differentiation. The patient was then referred to surgery for the
removal of the BCC. Analysis of the specimen showed free surgical margins and
the immunohistochemical panel did not confirm the initial diagnosis of BCC,
indicating a subtype of BSC. After surgery, the patient has been followed by
periodic consultations. She is well and without further complications.Coments: BSC
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