This review gives a brief summary of the field of gold nanoparticle interactions with biological molecules, particularly those with possible catalytic relevance. Gold nanoparticles are well known as catalysts in organic chemistry but much is unknown regarding their potential as catalysts of reactions involving biological molecules such as protein and nucleic acids. Biological molecules may be the substrate for catalysis or, if they are the ligand coating the gold particle, may be the catalyst itself. In other cases biological molecules may form a template upon which gold nanoparticles can be precisely arrayed. As relatively little is currently known about the catalytic capabilities of gold nanoparticles in this area, this review will consider templating in general (including, but not restricted to, those which result in structures having potential as catalysts) before going on to consider firstly catalysis by the gold nanoparticle itself followed by catalysis by ligands attached to gold nanoparticles, all considered with a focus on biological molecules.
References
[1]
Faraday, M. The Bakerian lecture: experimental relations of gold (and other metals) to light. Philos. Trans. R. Soc. London 1857, 147, 145–181, doi:10.1098/rstl.1857.0011.
[2]
Edwards, P.P.; Thomas, J.M. Gold in a metallic divided state—From Faraday to present-day nanoscience. Angew. Chem. Int. Ed. 2007, 46, 5480–5486, doi:10.1002/anie.200700428.
[3]
Tweney, R.D. Discovering discovery: how Faraday found the first metallic colloid. Perspect. Sci. 2006, 14, 97–121, doi:10.1162/posc.2006.14.1.97.
[4]
Haruta, M.; Kobayashi, T.; Sano, H.; Yamada, N. Novel gold catalysts for the oxidation of carbon monoxide at a temperature far below 0 °C. Chem. Lett. 1987, 16, 405–408.
[5]
Turkevich, J.; Stevenson, P.C.; Hillier, J. A study of the nucleation and growth processes in the synthesis of colloidal gold. Discuss. Faraday Soc. 1951, 11, 55–75, doi:10.1039/df9511100055.
[6]
Enustun, B.V.; Turkevich, J. Coagulation of colloidal gold. J. Am. Chem. Soc. 1963, 85, 3317–3328, doi:10.1021/ja00904a001.
[7]
Turkevich, J. Colloidal gold. Part I. Gold Bull. 1985, 18, 86–91, doi:10.1007/BF03214690.
[8]
Brust, M.; Walker, M.; Bethell, D.; Schiffrin, D.J.; Whyman, R. Synthesis of thiol-derivatised gold nanoparticles in a two-phase Liquid-Liquid system. J. Chem. Soc. Chem. Commun. 1994, 801–802.
[9]
Grzelczak, M.; Perez-Juste, J.; Mulvaney, P.; Liz-Marzan, L.M. Shape control in gold nanoparticle synthesis. Chem. Soc. Rev. 2008, 37, 1783–1791, doi:10.1039/b711490g.
[10]
Pan, Y.; Neuss, S.; Leifert, A.; Fischler, M.; Wen, F.; Simon, U.; Schmid, G.; Brandau, W.; Jahnen-Dechent, W. Size-dependent cytotoxicity of gold nanoparticles. Small 2007, 3, 1941–1949, doi:10.1002/smll.200700378.
[11]
Pan, Y.; Leifert, A.; Ruau, D.; Neuss, S.; Bornemann, J.; Schmid, G.; Brandau, W.; Simon, U.; Jahnen-Dechent, W. Gold nanoparticles of diameter 1.4 ？nm trigger necrosis by oxidative stress and mitochondrial damage. Small 2009, 5, 2067–2076, doi:10.1002/smll.200900466.
[12]
Hoa, X.D.; Kirk, A.G.; Tabrizian, M. Towards integrated and sensitive surface plasmon resonance biosensors: A review of recent progress. Biosens. Bioelectron. 2007, 23, 151–160, doi:10.1016/j.bios.2007.07.001.
[13]
Liedberg, B.; Nylander, C.; Lunstr？m, I. Surface plasmon resonance for gas detection and biosensing. Sens. Actuators 1983, 4, 299–304, doi:10.1016/0250-6874(83)85036-7.
Kelly, K.L.; Coronado, E.; Zhao, L.L.; Schatz, G.C. The Optical Properties of metal nanoparticles: The influence of size, shape, and dielectric environment. J. Phys. Chem. B 2002, 107, 668–677.
[16]
Dusemund, B.; Hoffmann, A.; Salzmann, T.; Kreibig, U.; Schmid, G. Cluster matter: The transition of optical elastic scattering to regular reflection. Z. Phys. D 1991, 20, 305–308.
[17]
Katz, E.; Willner, I. Integrated nanoparticle-biomolecule hybrid systems: Synthesis, properties, and applications. Angew. Chem. Int. Ed. 2004, 43, 6042–6108, doi:10.1002/anie.200400651.
[18]
Saha, K.; Agasti, S.S.; Kim, C.; Li, X.; Rotello, V.M. Gold nanoparticles in chemical and biological sensing. Chem. Rev. 2012, 112, 2739–2779, doi:10.1021/cr2001178.
[19]
Stockman, M.I. Nanoplasmonics: Past, present, and glimpse into future. Opt. Express. 2011, 19, 22029–22106, doi:10.1364/OE.19.022029.
[20]
Tanaka, R.; Yuhi, T.; Nagatani, N.; Endo, T.; Kerman, K.; Takamura, Y.; Tamiya, E. A novel enhancement assay for immunochromatographic test strips using gold nanoparticles. Anal. Bioanal. Chem. 2006, 385, 1414–1420, doi:10.1007/s00216-006-0549-4.
[21]
Cole, J.R.; Mirin, N.A.; Knight, M.W.; Goodrich, G.P.; Halas, N.J. Photothermal efficiencies of nanoshells and nanorods for clinical therapeutic applications. J. Phys. Chem. C 2009, 113, 12090–12094, doi:10.1021/jp9003592.
[22]
Jain, P.K.; Lee, K.S.; El-Sayed, I.H.; El-Sayed, M.A. Calculated absorption and scattering properties of gold nanoparticles of different size, shape, and composition: applications in biological imaging and biomedicine. J. Phys. Chem. B 2006, 110, 7238–7248, doi:10.1021/jp057170o.
[23]
Loo, C.; Lin, A.; Hirsch, L.; Lee, M.H.; Barton, J.; Halas, N.; West, J.; Drezek, R. Nanoshell-enabled photonics-based imaging and therapy of cancer. Technol. Cancer Res. Treat. 2004, 3, 33–40.
[24]
O'Neal, D.P.; Hirsch, L.R.; Halas, N.J.; Payne, J.D.; West, J.L. Photo-thermal tumor ablation in mice using near infrared-absorbing nanoparticles. Cancer Lett. 2004, 209, 171–176, doi:10.1016/j.canlet.2004.02.004.
[25]
Hirsch, L.R.; Stafford, R.J.; Bankson, J.A.; Sershen, S.R.; Rivera, B.; Price, R.E.; Hazle, J.D.; Halas, N.J.; West, J.L. Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance. Proc. Natl. Acad. Sci. USA 2003, 100, 13549–13554, doi:10.1073/pnas.2232479100.
[26]
Cardinal, J.; Klune, J.R.; Chory, E.; Jeyabalan, G.; Kanzius, J.S.; Nalesnik, M.; Geller, D.A. Noninvasive radiofrequency ablation of cancer targeted by gold nanoparticles. Surgery 2008, 144, 125–132, doi:10.1016/j.surg.2008.03.036.
Watson, J.D.; Crick, F.H. Molecular structure of nucleic acids; A structure for deoxyribose nucleic acid. Nature 1953, 171, 737–738, doi:10.1038/171737a0.
[30]
Alivisatos, A.; Johnsson, K.; Peng, X.; Wilson, T.; Loweth, C.; Bruchez, M.; Schultz, P. Organization of ‘nanocrystal molecules’ using DNA. Nature 1996, 382, 609–611, doi:10.1038/382609a0.
[31]
Pinto, Y.Y.; Le, J.D.; Seeman, N.C.; Musier-Forsyth, K.; Taton, T.A.; Kiehl, R.A. Sequence-encoded self-assembly of multiple-nanocomponent arrays by 2D DNA scaffolding. Nano Lett. 2005, 5, 2399–2402, doi:10.1021/nl0515495.
[32]
Zheng, J.; Constantinou, P.E.; Micheel, C.; Alivisatos, A.P.; Kiehl, R.A.; Seeman, N.C. Two-dimensional nanoparticle arrays show the organizational power of robust DNA motifs. Nano Lett. 2006, 6, 1502–1504, doi:10.1021/nl060994c.
[33]
Sharma, J.; Chhabra, R.; Liu, Y.; Ke, Y.; Yan, H. DNA-templated self-assembly of two-dimensional and periodical gold nanoparticle arrays. Angew. Chem. Int. Ed. 2006, 45, 730–735, doi:10.1002/anie.200503208.
[34]
Lee, J.H.; Wernette, D.P.; Yigit, M.V.; Liu, J.; Wang, Z.; Lu, Y. Site-specific control of distances between gold nanoparticles using phosphorothioate anchors on DNA and a short bifunctional molecular fastener. Angew. Chem. Int. Ed. 2007, 46, 9006–9010, doi:10.1002/anie.200702569.
[35]
Ludue？a, R.F.; Roach, M.C.; Trcka, P.P.; Weintraub, S. N,N-Bis(α-iodoacetyl)-2,2′-dithiobis(ethylamine), a reversible crosslinking reagent for protein sulfhydryl groups. Anal. Biochem. 1981, 117, 76–80, doi:10.1016/0003-2697(81)90694-1.
[36]
Ozbay, E. Plasmonics: Merging photonics and electronics at nanoscale dimensions. Science 2006, 311, 189–193, doi:10.1126/science.1114849.
[37]
Liu, Z.; Searson, P.C. Single nanoporous gold nanowire sensors. J. Phys. Chem. B 2006, 110, 4318–4322, doi:10.1021/jp056940t.
[38]
Chirea, M.; Freitas, A.; Vasile, B.S.; Ghitulica, C.; Pereira, C.M.; Silva, F. Gold nanowire networks: Synthesis, characterization, and catalytic activity. Langmuir 2011, 27, 3906–3913, doi:10.1021/la104092b.
[39]
Bai, X.; Gao, Y.; Liu, H.-g.; Zheng, L. Synthesis of amphiphilic ionic liquids terminated gold nanorods and their superior catalytic activity for the reduction of nitro compounds. J. Phys. Chem. C 2009, 113, 17730–17736, doi:10.1021/jp906378d.
[40]
Richter, J. Metallization of DNA. Physica E 2003, 16, 157–173, doi:10.1016/S1386-9477(02)00670-7.
[41]
Ongaro, A.; Griffin, F.; Beecher, P.; Nagle, L.; Iacopino, D.; Quinn, A.; Redmond, G.; Fitzmaurice, D. DNA-Templated Assembly of Conducting Gold Nanowires between Gold Electrodes on a Silicon Oxide Substrate. Chem. Mater. 2005, 17, 1959–1964, doi:10.1021/cm047970w.
[42]
Kim, H.J.; Roh, Y.; Hong, B. Selective Formation of a Latticed Nanostructure with the Precise Alignment of DNA-Templated Gold Nanowires. Langmuir 2010, 26, 18315–18319, doi:10.1021/la101086h.
[43]
Harnack, O.; Ford, W.E.; Yasuda, A.; Wessels, J.M. Tris(hydroxymethyl)phosphine-Capped Gold Particles Templated by DNA as Nanowire Precursors. Nano Lett. 2002, 2, 919–923, doi:10.1021/nl020259a.
[44]
Yonezawa, T.; Onoue, S.-y.; Kimizuka, N. Metal Coating of DNA Molecules by Cationic, Metastable Gold Nanoparticles. Chem. Lett. 2002, 31, 1172–1173, doi:10.1246/cl.2002.1172.
[45]
Patolsky, F.; Weizmann, Y.; Lioubashevski, O.; Willner, I. Au-Nanoparticle Nanowires Based on DNA and Polylysine Templates. Angew. Chem. Int. Ed. 2002, 41, 2323–2327, doi:10.1002/1521-3773(20020703)41:13<2323::AID-ANIE2323>3.0.CO;2-H.
[46]
Haruta, M. Catalysis of Gold Nanoparticles Deposited on Metal Oxides. CATTECH 2002, 6, 102–115, doi:10.1023/A:1020181423055.
Ding, B.; Sha, R.; Seeman, N.C. Pseudohexagonal 2D DNA Crystals from Double Crossover Cohesion. J. Am. Chem. Soc. 2004, 126, 10230–10231, doi:10.1021/ja047486u.
[49]
Le, J.D.; Pinto, Y.; Seeman, N.C.; Musier-Forsyth, K.; Taton, T.A.; Kiehl, R.A. DNA-Templated Self-Assembly of Metallic Nanocomponent Arrays on a Surface. Nano Lett. 2004, 4, 2343–2347, doi:10.1021/nl048635+.
[50]
Mastroianni, A.J.; Claridge, S.A.; Alivisatos, A.P. Pyramidal and Chiral Groupings of Gold Nanocrystals Assembled Using DNA Scaffolds. J. Am. Chem. Soc. 2009, 131, 8455–8459, doi:10.1021/ja808570g.
[51]
Chen, J.H.; Seeman, N.C. Synthesis from DNA of a molecule with the connectivity of a cube. Nature 1991, 350, 631–633, doi:10.1038/350631a0.
[52]
Erben, C.M.; Goodman, R.P.; Turberfield, A.J. A Self-Assembled DNA Bipyramid. J. Am. Chem. Soc. 2007, 129, 6992–6993, doi:10.1021/ja071493b.
[53]
Zhang, Y.; Seeman, N.C. Construction of a DNA-Truncated Octahedron. J. Am. Chem. Soc. 1994, 116, 1661–1669, doi:10.1021/ja00084a006.
[54]
Rothemund, P.W. Folding DNA to create nanoscale shapes and patterns. Nature 2006, 440, 297–302, doi:10.1038/nature04586.
[55]
Andersen, E.S.; Dong, M.; Nielsen, M.M.; Jahn, K.; Subramani, R.; Mamdouh, W.; Golas, M.M.; Sander, B.; Stark, H.; Oliveira, C.L.; et al. Self-assembly of a nanoscale DNA box with a controllable lid. Nature 2009, 459, 73–76, doi:10.1038/nature07971.
[56]
Kuzuya, A.; Komiyama, M. Design and construction of a box-shaped 3D-DNA origami. Chem. Commun. 2009, 4182–4184, doi:10.1039/b907800b.
Yang, C.; Manocchi, A.K.; Lee, B.; Yi, H. Viral templated palladium nanocatalysts for dichromate reduction. Appl. Catal. B 2010, 93, 282–291, doi:10.1016/j.apcatb.2009.10.001.
[59]
Nam, Y.S.; Magyar, A.P.; Lee, D.; Kim, J.-W.; Yun, D.S.; Park, H.; Pollom, T.S.; Weitz, D.A.; Belcher, A.M. Biologically templated photocatalytic nanostructures for sustained light-driven water oxidation. Nat. Nanotechnol. 2010, 5, 340–344, doi:10.1038/nnano.2010.57.
[60]
Scheibel, T.; Parthasarathy, R.; Sawicki, G.; Lin, X.-M.; Jaeger, H.; Lindquist, S.L. Conducting nanowires built by controlled self-assembly of amyloid fibers and selective metal deposition. Proc. Natl. Acad. Sci. USA 2003, 100, 4527–4532.
[61]
Glover, J.R.; Kowal, A.S.; Schirmer, E.C.; Patino, M.M.; Liu, J.J.; Lindquist, S. Self-seeded fibers formed by Sup35, the protein determinant of [PSI+], a heritable prion-like factor of S. cerevisiae. Cell 1997, 89, 811–819.
[62]
Steinmetz, N.F.; Evans, D.J. Utilisation of plant viruses in bionanotechnology. Org. Biomol. Chem. 2007, 5, 2891–2902, doi:10.1039/b708175h.
[63]
Lin, T.; Chen, Z.; Usha, R.; Stauffacher, C.V.; Dai, J.B.; Schmidt, T.; Johnson, J.E. The refined crystal structure of cowpea mosaic virus at 2.8 A resolution. Virology 1999, 265, 20–34, doi:10.1006/viro.1999.0038.
[64]
Steinmetz, N.F.; Lomonossoff, G.P.; Evans, D.J. Cowpea Mosaic Virus for Material Fabrication: Addressable Carboxylate Groups on a Programmable Nanoscaffold. Langmuir 2006, 22, 3488–3490, doi:10.1021/la060078e.
[65]
Steinmetz, N.F.; Lomonossoff, G.P.; Evans, D.J. Decoration of Cowpea Mosaic Virus with Multiple, Redox-Active, Organometallic Complexes. Small 2006, 2, 530–533, doi:10.1002/smll.200500453.
[66]
Blum, A.S.; Soto, C.M.; Wilson, C.D.; Cole, J.D.; Kim, M.; Gnade, B.; Chatterji, A.; Ochoa, W.F.; Lin, T.; Johnson, J.E.; et al. Cowpea Mosaic Virus as a Scaffold for 3-D Patterning of Gold Nanoparticles. Nano Lett. 2004, 4, 867–870, doi:10.1021/nl0497474.
[67]
Zafeiratos, S.; Piccinin, S.; Teschner, D. Alloys in catalysis: Phase separation and surface segregation phenomena in response to the reactive environment. Catal. Sci. Technol. 2012, 2, 1787–1801, doi:10.1039/c2cy00487a.
[68]
Evans, D.J. The bionanoscience of plant viruses: templates and synthons for new materials. J. Mater. Chem. 2008, 18, 3746–3754, doi:10.1039/b804305a.
[69]
Shenton, W.; Douglas, T.; Young, M.; Stubbs, G.; Mann, S. Inorganic-Organic Nanotube Composites from Template Mineralization of Tobacco Mosaic Virus. Adv. Mater. 1999, 11, 253–256, doi:10.1002/(SICI)1521-4095(199903)11:3<253::AID-ADMA253>3.0.CO;2-7.
[70]
Knez, M.; Kadri, A.; Wege, C.; G？sele, U.; Jeske, H.; Nielsch, K. Atomic Layer Deposition on Biological Macromolecules: Metal Oxide Coating of Tobacco Mosaic Virus and Ferritin. Nano Lett. 2006, 6, 1172–1177, doi:10.1021/nl060413j.
[71]
Dujardin, E.; Peet, C.; Stubbs, G.; Culver, J.N.; Mann, S. Organization of Metallic Nanoparticles Using Tobacco Mosaic Virus Templates. Nano Lett. 2003, 3, 413–417, doi:10.1021/nl034004o.
[72]
Lee, S.-Y.; Royston, E.; Culver, J.N.; Harris, M.T. Improved metal cluster deposition on a genetically engineered tobacco mosaic virus template. Nanotechnology 2005, 16, S435, doi:10.1088/0957-4484/16/7/019.
[73]
Lim, J.-S.; Kim, S.-M.; Lee, S.-Y.; Stach, E.A.; Culver, J.N.; Harris, M.T. Formation of Au/Pd Alloy Nanoparticles on TMV. J. Nanomater. 2010, 2010, doi:10.1155/2010/620505.
[74]
Khan, A.A.; Fox, E.K.; Gorzny, M.L.; Nikulina, E.; Brougham, D.F.; Wege, C.; Bittner, A.M. pH control of the electrostatic binding of gold and iron oxide nanoparticles to tobacco mosaic virus. Langmuir 2013, 29, 2094–2098, doi:10.1021/la3044126.
[75]
Guli, M.; Lambert, E.M.; Li, M.; Mann, S. Template-directed synthesis of nanoplasmonic arrays by intracrystalline metalization of cross-linked lysozyme crystals. Angew. Chem. Int. Ed. 2010, 49, 520–523, doi:10.1002/anie.200905070.
[76]
Wei, H.; Wang, Z.; Zhang, J.; House, S.; Gao, Y.G.; Yang, L.; Robinson, H.; Tan, L.H.; Xing, H.; Hou, C.; et al. Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme. Nat. Nanotechnol. 2011, 6, 93–97.
[77]
Wei, H.; Lu, Y. Catalysis of gold nanoparticles within lysozyme single crystals. Chem. Asian J. 2012, 7, 680–683, doi:10.1002/asia.201100942.
[78]
McMillan, R.A.; Paavola, C.D.; Howard, J.; Chan, S.L.; Zaluzec, N.J.; Trent, J.D. Ordered nanoparticle arrays formed on engineered chaperonin protein templates. Nat. Mater. 2002, 1, 247–252, doi:10.1038/nmat775.
[79]
Trent, J.D.; Kagawa, H.K.; Yaoi, T.; Olle, E.; Zaluzec, N.J. Chaperonin filaments: the archaeal cytoskeleton? Proc. Natl. Acad. Sci. USA 1997, 94, 5383–5388, doi:10.1073/pnas.94.10.5383.
[80]
Ellis, M.J.; Knapp, S.; Koeck, P.J.B.; Fakoor-Biniaz, Z.; Ladenstein, R.; Hebert, H. Two-Dimensional Crystallization of the Chaperonin TF55 from the Hyperthermophilic ArchaeonSulfolobus solfataricus. J. Struct. Biol. 1998, 123, 30–36, doi:10.1006/jsbi.1998.4002.
[81]
Bond, G.C.; Louis, C.; Thompson, D.T. Catalysis by Gold; Imperial College Press: London, UK, 2006; Volume 6.
Della Pina, C.; Falletta, E.; Rossi, M. Update on selective oxidation using gold. Chem. Soc. Rev. 2012, 41, 350–369, doi:10.1039/c1cs15089h.
[84]
Mills, G.; Gordon, M.S.; Metiu, H. Oxygen adsorption on Au clusters and a rough Au(111) surface: The role of surface flatness, electron confinement, excess electrons, and band gap. J. Chem. Phys. 2003, 118, 4198–4205, doi:10.1063/1.1542879.
Benkovic, S.J.; Hammes-Schiffer, S. A perspective on enzyme catalysis. Science 2003, 301, 1196–1202, doi:10.1126/science.1085515.
[90]
Comotti, M.; Della Pina, C.; Matarrese, R.; Rossi, M. The catalytic activity of “naked” gold particles. Angew. Chem. Int. Ed. 2004, 43, 5812–5815, doi:10.1002/anie.200460446.
[91]
Boronat, M.; Corma, A. Oxygen activation on gold nanoparticles: Separating the influence of particle size, particle shape and support interaction. Dalton Trans. 2010, 39, 8538–8546, doi:10.1039/c002280b.
[92]
Kotov, N.A. Inorganic Nanoparticles as Protein Mimics. Science 2010, 330, 188–189, doi:10.1126/science.1190094.
[93]
Witt, S.; Wohlfahrt, G.; Schomburg, D.; Hecht, H.J.; Kalisz, H.M. Conserved arginine-516 of Penicillium amagasakiense glucose oxidase is essential for the efficient binding of beta-D-glucose. Biochem. J. 2000, 347, 553–559, doi:10.1042/0264-6021:3470553.
[94]
Wild, S.; Roglic, G.; Green, A.; Sicree, R.; King, H. Global Prevalence of Diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care 2004, 27, 1047–1053, doi:10.2337/diacare.27.5.1047.
[95]
Zheng, X.; Liu, Q.; Jing, C.; Li, Y.; Li, D.; Luo, W.; Wen, Y.; He, Y.; Huang, Q.; Long, Y.T.; et al. Catalytic gold nanoparticles for nanoplasmonic detection of DNA hybridization. Angew. Chem. Int. Ed. 2011, 50, 11994–11998, doi:10.1002/anie.201105121.
[96]
Newman, J.D.; Turner, A.P.F. Home blood glucose biosensors: A commercial perspective. Biosens. Bioelectron. 2005, 20, 2435–2453, doi:10.1016/j.bios.2004.11.012.
[97]
Beltrame, P.; Comotti, M.; Della Pina, C.; Rossi, M. Aerobic oxidation of glucose: II. Catalysis by colloidal gold. Appl. Catal. A 2006, 297, 1–7, doi:10.1016/j.apcata.2005.08.029.
[98]
Biella, S.; Prati, L.; Rossi, M. Selective Oxidation of d-Glucose on Gold Catalyst. J. Catal. 2002, 206, 242–247, doi:10.1006/jcat.2001.3497.
[99]
Luo, W.; Zhu, C.; Su, S.; Li, D.; He, Y.; Huang, Q.; Fan, C. Self-Catalyzed, Self-Limiting Growth of Glucose Oxidase-Mimicking Gold Nanoparticles. ACS Nano 2010, 4, 7451–7458, doi:10.1021/nn102592h.
[100]
Li, H.; Rothberg, L. Colorimetric detection of DNA sequences based on electrostatic interactions with unmodified gold nanoparticles. Proc. Natl. Acad. Sci. USA 2004, 101, 14036–14039, doi:10.1073/pnas.0406115101.
[101]
Li, H.; Rothberg, L.J. Label-Free Colorimetric Detection of Specific Sequences in Genomic DNA Amplified by the Polymerase Chain Reaction. J. Am. Chem. Soc. 2004, 126, 10958–10961, doi:10.1021/ja048749n.
[102]
Cedervall, T.; Lynch, I.; Lindman, S.; Berggard, T.; Thulin, E.; Nilsson, H.; Dawson, K.; Linse, S. Understanding the nanoparticle-protein corona using methods to quntify exchange rates and affinities of proteins for nanoparticles. Proc. Natl. Acad. Sci. USA 2007, 104, 2050–2055.
[103]
Lacerda, S.H.D.P.; Park, J.J.; Meuse, C.; Pristinski, D.; Becker, M.L.; Karim, A.; Douglas, J.F. Interaction of Gold Nanoparticles with Common Human Blood Proteins. ACS Nano 2009, 4, 365–379.
[104]
Rocker, C.; Potzl, M.; Zhang, F.; Parak, W.J.; Nienhaus, G.U. A quantitative fluorescence study of protein monolayer formation on colloidal nanoparticles. Nat. Nanotechnol. 2009, 4, 577–580, doi:10.1038/nnano.2009.195.
[105]
Babitzke, P.; Gollnick, P. Posttranscription initiation control of tryptophan metabolism in Bacillus subtilis by the trp RNA-binding attenuation protein (TRAP), anti-TRAP, and RNA structure. J. Bacteriol. 2001, 183, 5795–5802, doi:10.1128/JB.183.20.5795-5802.2001.
[106]
Chen, X.; Antson, A.A.; Yang, M.; Li, P.; Baumann, C.; Dodson, E.J.; Dodson, G.G.; Gollnick, P. Regulatory features of the trp operon and the crystal structure of the trp RNA-binding attenuation protein from Bacillus stearothermophilus. J. Mol. Biol. 1999, 289, 1003–1016, doi:10.1006/jmbi.1999.2834.
[107]
Antson, A.A.; Otridge, J.; Brzozowski, A.M.; Dodson, E.J.; Dodson, G.G.; Wilson, K.S.; Smith, T.M.; Yang, M.; Kurecki, T.; Gollnick, P. The structure of trp RNA-binding attenuation protein. Nature 1995, 374, 693–700, doi:10.1038/374693a0.
[108]
Heddle, J.G.; Okajima, T.; Scott, D.J.; Akashi, S.; Park, S.Y.; Tame, J.R. Dynamic allostery in the ring protein TRAP. J. Mol. Biol. 2007, 371, 154–167, doi:10.1016/j.jmb.2007.05.013.
[109]
Heddle, J.G.; Yokoyama, T.; Yamashita, I.; Park, S.Y.; Tame, J.R. Rounding up: Engineering 12-membered rings from the cyclic 11-mer TRAP. Structure 2006, 14, 925–933, doi:10.1016/j.str.2006.03.013.
[110]
Heddle, J.G.; Fujiwara, I.; Yamadaki, H.; Yoshii, S.; Nishio, K.; Addy, C.; Yamashita, I.; Tame, J.R. Using the ring-shaped protein TRAP to capture and confine gold nanodots on a surface. Small 2007, 3, 1950–1956, doi:10.1002/smll.200700400.
[111]
Miranda, F.F.; Iwasaki, K.; Akashi, S.; Sumitomo, K.; Kobayashi, M.; Yamashita, I.; Tame, J.R.H.; Heddle, J.G. A Self-Assembled Protein Nanotube with High Aspect Ratio. Small 2009, 5, 2077–2084, doi:10.1002/smll.200900667.
[112]
Malay, A.D.; Heddle, J.G.; Tomita, S.; Iwasaki, K.; Miyazaki, N.; Sumitomo, K.; Yanagi, H.; Yamashita, I.; Uraoka, Y. Gold Nanoparticle-Induced Formation of Artificial Protein Capsids. Nano Lett. 2012, 12, 2056–2059, doi:10.1021/nl3002155.
[113]
Wittstock, A.; Zielasek, V.; Biener, J.; Friend, C.M.; Baumer, M. Nanoporous gold catalysts for selective gas-phase oxidative coupling of methanol at low temperature. Science 2010, 327, 319–322, doi:10.1126/science.1183591.
[114]
Hakkinen, H. The gold-sulfur interface at the nanoscale. Nat. Chem. 2012, 4, 443–455, doi:10.1038/nchem.1352.
[115]
Zhang, D.; Neumann, O.; Wang, H.; Yuwono, V.M.; Barhoumi, A.; Perham, M.; Hartgerink, J.D.; Wittung-Stafshede, P.; Halas, N.J. Gold Nanoparticles Can Induce the Formation of Protein-based Aggregates at Physiological pH. Nano Lett. 2009, 9, 666–671, doi:10.1021/nl803054h.
[116]
Aubin-Tam, M.E.; Hamad-Schifferli, K. Structure and function of nanoparticle-protein conjugates. Biomed. Mater. 2008, 3, 034001, doi:10.1088/1748-6041/3/3/034001.
[117]
Treuel, L.; Malissek, M.; Gebauer, J.S.; Zellner, R. The Influence of Surface Composition of Nanoparticles on their Interactions with Serum Albumin. ChemPhysChem 2010, 11, 3093–3099, doi:10.1002/cphc.201000174.
Pingoud, A.; Fuxreiter, M.; Pingoud, V.; Wende, W. Type II restriction endonucleases: Structure and mechanism. Cell. Mol. Life Sci. 2005, 62, 685–707, doi:10.1007/s00018-004-4513-1.
[123]
Pommier, Y.; Leo, E.; Zhang, H.; Marchand, C. DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs. Chem. Biol. 2010, 17, 421–433, doi:10.1016/j.chembiol.2010.04.012.
[124]
Zaupa, G.; Mora, C.; Bonomi, R.; Prins, L.J.; Scrimin, P. Catalytic self-assembled monolayers on Au nanoparticles: The source of catalysis of a transphosphorylation reaction. Chemistry A 2011, 17, 4879–4889.
[125]
Pengo, P.; Polizzi, S.; Pasquato, L.; Scrimin, P. Carboxylate-imidazole cooperativity in dipeptide-functionalized gold nanoparticles with esterase-like activity. J. Am. Chem. Soc. 2005, 127, 1616–1617, doi:10.1021/ja043547c.
[126]
Northrop, D.B. Follow the Protons:？ A Low-Barrier Hydrogen Bond Unifies the Mechanisms of the Aspartic Proteases. Acc. Chem. Res. 2001, 34, 790–797, doi:10.1021/ar000184m.
[127]
Hsu, M.H.; Josephrajan, T.; Yeh, C.S.; Shieh, D.B.; Su, W.C.; Hwu, J.R. Novel arylhydrazone-conjugated gold nanoparticles with DNA-cleaving ability: The first DNA-nicking nanomaterial. Bioconj. Chem. 2007, 18, 1709–1712, doi:10.1021/bc700222n.
[128]
Hwu, J.R.; Chieh Lin, C.; Hsien Chuang, S.; Yung King, K.; Su, T.-R.; Tsay, S.-C. Aminyl and iminyl radicals from arylhydrazones in the photo-induced DNA cleavage. Bioorg. Med. Chem. 2004, 12, 2509–2515, doi:10.1016/j.bmc.2004.03.037.
[129]
Bonomi, R.; Selvestrel, F.; Lombardo, V.; Sissi, C.; Polizzi, S.; Mancin, F.; Tonellato, U.; Scrimin, P. Phosphate diester and DNA hydrolysis by a multivalent, nanoparticle-based catalyst. J. Am. Chem. Soc. 2008, 130, 15744–15745, doi:10.1021/ja801794t.
[130]
Fillon, Y.; Verma, A.; Ghosh, P.; Ernenwein, D.; Rotello, V.M.; Chmielewski, J. Peptide ligation catalyzed by functionalized gold nanoparticles. J. Am. Chem. Soc. 2007, 129, 6676–6677, doi:10.1021/ja070301+.
[131]
Dawson, P.; Muir, T.; Clark-Lewis, I.; Kent, S. Synthesis of proteins by native chemical ligation. Science 1994, 266, 776–779.
[132]
Yarus, M. Getting past the RNA world: The initial Darwinian ancestor. Cold Spring Harb. Perspect. Biol. 2011, doi:10.1101/cshperspect.a003590.
[133]
Silverman, S.K. Deoxyribozymes: DNA catalysts for bioorganic chemistry. Org. Biomol. Chem. 2004, 2, 2701–2706, doi:10.1039/b411910j.
Lee, J.H.; Wang, Z.; Liu, J.; Lu, Y. Highly sensitive and selective colorimetric sensors for uranyl (UO2(2+)): Development and comparison of labeled and label-free DNAzyme-gold nanoparticle systems. J. Am. Chem. Soc. 2008, 130, 14217–14226, doi:10.1021/ja803607z.
[136]
Lu, Y.; Liu, J. Functional DNA nanotechnology: Emerging applications of DNAzymes and aptamers. Curr. Opin. Biotech. 2006, 17, 580–588, doi:10.1016/j.copbio.2006.10.004.
[137]
Zhao, W.; Lam, J.C.; Chiuman, W.; Brook, M.A.; Li, Y. Enzymatic cleavage of nucleic acids on gold nanoparticles: A generic platform for facile colorimetric biosensors. Small 2008, 4, 810–816, doi:10.1002/smll.200700757.
[138]
Santoro, S.W.; Joyce, G.F. A general purpose RNA-cleaving DNA enzyme. Proc. Natl. Acad. Sci. USA 1997, 94, 4262–4266, doi:10.1073/pnas.94.9.4262.
[139]
Li, J.; Lu, Y. A Highly Sensitive and Selective Catalytic DNA Biosensor for Lead Ions. J. Am. Chem. Soc. 2000, 122, 10466–10467, doi:10.1021/ja0021316.
[140]
Liu, J.; Lu, Y. A Colorimetric Lead Biosensor Using DNAzyme-Directed Assembly of Gold Nanoparticles. J. Am. Chem. Soc. 2003, 125, 6642–6643, doi:10.1021/ja034775u.
[141]
Brennan, J.L.; Hatzakis, N.S.; Tshikhudo, T.R.; Dirvianskyte, N.; Razumas, V.; Patkar, S.; Vind, J.; Svendsen, A.; Nolte, R.J.; Rowan, A.E.; et al. Bionanoconjugation via click chemistry: The creation of functional hybrids of lipases and gold nanoparticles. Bioconj. Chem. 2006, 17, 1373–1375, doi:10.1021/bc0601018.
[142]
Prati, L.; Spontoni, P.; Gaiassi, A. From Renewable to Fine Chemicals Through Selective Oxidation: The Case of Glycerol. Top. Catal. 2009, 52, 288–296, doi:10.1007/s11244-008-9165-1.
[143]
Villa, A.; Wang, D.; Su, D.S.; Prati, L. Gold Sols as Catalysts for Glycerol Oxidation: The Role of Stabilizer. ChemCatChem 2009, 1, 510–514, doi:10.1002/cctc.200900118.
