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Algorithms  2013 

Multi-Sided Compression Performance Assessment of ABI SOLiD WES Data

DOI: 10.3390/a6020309

Keywords: data compression, genomics, next-generation sequencing, SOLiD

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Abstract:

Data storage is a major and growing part of IT budgets for research since manyyears. Especially in biology, the amount of raw data products is growing continuously,and the advent of the so-called "next-generation" sequencers has made things worse.Affordable prices have pushed scientists to massively sequence whole genomes and to screenlarge cohort of patients, thereby producing tons of data as a side effect. The need formaximally fitting data into the available storage volumes has encouraged and welcomednew compression algorithms and tools. We focus here on state-of-the-art compression toolsand measure their compression performance on ABI SOLiD data.

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