Aim. To determine the score and frequency of premenstrual syndrome (PMS) among female college students and to detect the possible risk factors of PMS. A trial of life style modification regarding prevention and control of PMS symptoms was carried out using counseling. Materials and Methods. A cross-sectional study was conducted on 253 El-Minia University unmarried female students. A self-administered questionnaire inquiring about symptoms of PMS in the previous three months and risk factors possibly related to it was used. PMS score was calculated. Multiple regression analysis was performed to determine which of several biopsychosocial and dietary factors influenced PMS. Life style modification counseling was done to prevent and control PMS. Results. The study revealed that 80.2% of the participants experienced various degrees of PMS symptoms which were significantly associated with a family history of PMS, physical inactivity, habitual excess consumption of coffee, BMI, frequent consumption of fast food, and smoking, but these factors explained only 52% of the variability in the logistic regression model. Conclusion. We recommend the introduction of a reproductive health component into school and college health education programs and encourage female adolescents and young adults to adopt a healthy behavior. 1. Introduction Premenstrual tension syndrome (PMS) is one of the most common disorders in women at reproductive age that could significantly interfere with activities of daily life. PMS is a set of physical and psychological symptoms that arises about a week to ten days before menstruation. Premenstrual symptoms usually relieve or ease once menstruation starts. But they might continue for the first few days of the period. If the problem really is PMS, though, it will go away and then it will come back with the next cycle [1]. Menstruation is a normal phenomenon which is an important indicator of women's health [2]. However, data on experiences of menstruation and its impact on the health status, quality of life, and social integration among women in developing countries are scant [3]. The American College of Obstetrics and Gynecology (ACOG) published the diagnostic criteria for PMS. It is considered if at least one of the 6 affective and one of the 4 somatic symptoms are reported 5 days prior to onset of menses in prior 3 cycles and cease within 4 days of onset of menses. There are numerous emotional and behavioral symptoms such as depression, angry outbursts, irritability, crying spells, anxiety, confusion, social withdrawal, poor concentration,
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