Though enlargement of the bony orbit by orbital decompression surgery has been known for about a century, surgical techniques vary all around the world mostly depending on the patient's clinical presentation but also on the institutional habits or the surgeon's skills. Ideally every surgical intervention should be tailored to the patient's specific needs. Therefore the aim of this paper is to review outcomes, hints, trends, and perspectives in orbital decompression surgery in thyroid eye disease regarding different surgical techniques. 1. Introduction Thyroid-associated orbitopathy (TAO) can be functionally disabling and, in severe cases, may result in permanent visual loss. It may also cause significant facial disfigurement. Although many authors use the term “cosmetic decompression,” it must be kept in mind that this in fact represents reconstructive surgery because it addresses an abnormality caused by a disease. While decompression surgery has the potential to improve facial appearance, patients should be carefully informed that it is often impossible to restore their look to what it has been before the disease began to modify the tissues involved. Frequently multiple surgical procedures are required, ranging from orbital decompression surgery via strabismus surgery to lid surgery, again emphasizing that these procedures are not performed for the purpose of “beautification” [1]. It is important to note that most TAO patients will not require surgical treatment. In 1996 Bartley et al. [2] demonstrated that only 20% of their patients had one or more surgical procedures. The cumulative probability of having surgery was initially 5% by 1 year after first diagnosis of the disease, rising to 9.3% by 2 years, to 15.9% by 5 years, and to 21.8% by 10 years. The need for surgery was significantly related to age, with a 2.6 times greater overall risk in patients older than 50 years. Medical (immunosuppressive) measures are the first-line treatment in the active stage of TAO. In the in-active stage of the disease or if medical therapy fails in sight threatening situations in active eye disease, the surgeon will be called upon to improve the patient’s condition. This paper aims to review historical aspects and recent advances in decompression surgery in thyroid associated orbitopathy. 2. Clinical Findings and Indications for Orbital Decompression Treatment of TAO requires an accurate assessment of disease activity, temporal progression, and severity. The aim of diagnosis is to differentiate the active stage—which represents a potential threatening of visual
References
[1]
D. R. Meyer, “Surgical management of Graves orbitopathy,” Current Opinion in Ophthalmology, vol. 10, no. 5, pp. 343–351, 1999.
[2]
G. B. Bartley, V. Fatourechi, E. F. Kadrmas et al., “The treatment of Graves' ophthalmopathy in an incidence cohort,” American Journal of Ophthalmology, vol. 121, no. 2, pp. 200–206, 1996.
[3]
W. M. Wiersinga and M. F. Prummel, “Graves' ophthalmopathy: a rational approach to treatment,” Trends in Endocrinology and Metabolism, vol. 13, no. 7, pp. 280–287, 2002.
[4]
L. Bartalena, L. Baldeschi, A. J. Dickinson et al., “Consensus statement of the European group on Graves' orbitopathy (EUGOGO) on management of Graves' orbitopathy,” Thyroid, vol. 18, no. 3, pp. 333–346, 2008.
[5]
D. Char, Thyroid Eye Disease, Butterworth-Heinemann, Boston, Mass, USA, 3rd edition, 1997.
[6]
A. Eckstein, B. Quadbeck, G. Mueller et al., “Impact of smoking on the response to treatment of thyroid associated ophthalmopathy,” British Journal of Ophthalmology, vol. 87, no. 6, pp. 773–776, 2003.
[7]
I. M. Wakelkamp, L. Baldeschi, P. Saeed, M. P. Mourits, M. F. Prummel, and W. M. Wiersinga, “Surgical or medical decompression as a first-line treatment of optic neuropathy in Graves' ophthalmopathy? A randomized controlled trial,” Clinical Endocrinology, vol. 63, no. 3, pp. 323–328, 2005.
[8]
L. Baldeschi, I. M. M. J. Wakelkamp, R. Lindeboom, M. F. Prummel, and W. M. Wiersinga, “Early versus late orbital decompression in Graves' orbitopathy. A retrospective study in 125 patients,” Ophthalmology, vol. 113, no. 5, pp. 874–878, 2006.
[9]
M. Schittkowski, N. Fichter, and R. Guthoff, “Strabismus surgery in thyroid ophthalmopathy—dose-effect relationships and functional results,” Klinische Monatsblatter für Augenheilkunde, vol. 221, no. 11, pp. 941–947, 2004.
[10]
J. A. Fleishman, R. W. Beck, and R. O. Hoffman, “Orbital emphysema as an ophthalmologic emergency,” Ophthalmology, vol. 91, no. 11, pp. 1389–1391, 1984.
[11]
V. Kratky, J. J. Hurwitz, and D. R. Avram, “Orbital compartment syndrome. Direct measurement of orbital tissue pressure: 1. Technique,” Canadian Journal of Ophthalmology, vol. 25, no. 6, pp. 293–297, 1990.
[12]
C. D. Riemann, J. A. Foster, and G. S. Kosmorsky, “Direct orbital manometry in healthy patients,” Ophthalmic Plastic and Reconstructive Surgery, vol. 15, no. 2, pp. 121–125, 1999.
[13]
C. D. Riemann, J. A. Foster, and G. S. Kosmorsky, “Direct orbital manometry in patients with thyroid-associated orbitopathy,” Ophthalmology, vol. 106, no. 7, pp. 1296–1302, 1999.
[14]
N. Fichter, M. P. Schittkowski, H. P. Vick, and R. F. Guthoff, “Lateral orbital decompression for Graves' orbitopathy. Indication, surgical technique, and treatment success,” Ophthalmologe, vol. 101, no. 4, pp. 339–349, 2004.
[15]
R. J. Stanley, T. V. McCaffrey, K. P. Offord, and L. W. DeSanto, “Superior and transantral orbital decompression procedures. Effects on increased intraorbital pressure and orbital dynamics,” Archives of Otolaryngology, vol. 115, no. 3, pp. 369–373, 1989.
[16]
W. Schroeder, “Topographical diagnosis of orbital lesions with contact B-scan ultrasonography,” Klinische Monatsbl?tter für Augenheilkunde, vol. 172, no. 1, pp. 12–19, 1978.
[17]
M. F. Prummel, M. S. A. Suttorp-Schulten, W. M. Wiersinga, A. M. Verbeek, M. P. Mourits, and L. Koornneef, “A new ultrasonographic method to detect disease activity and predict response to immunosuppressive treatment in Graves ophthalmopathy,” Ophthalmology, vol. 100, no. 4, pp. 556–561, 1993.
[18]
E. C. Kirsch, A. H. Kaim, M. G. De Oliveira, and G. Von Arx, “Correlation of signal intensity ratio on orbital MRI-TIRM and clinical activity score as a possible predictor of therapy response in Graves' orbitopathy—a pilot study at 1.5 T,” Neuroradiology, vol. 52, no. 2, pp. 91–97, 2010.
[19]
J. Dollinger, “Die drickentlastlung der augenhokle durch entfurnung der ausseren orbitalwand bei hochgradiegen exophthalmos und konsekutwer hornhauterkronkung,” Deutsche Medizinische Wochenschrift, vol. 37, pp. 1888–1890, 1911.
[20]
R. Kroenlein, “Zur pathologie und operativen behandlung der dermoidcysten der orbita,” Orbita, vol. 4, p. 149, 1888.
[21]
H. C. Naffziger, “Progressive exophthalmos following thyroidectomy, its pathology and treatment,” Annals of Surgery, vol. 94, no. 4, pp. 582–586, 1931.
[22]
S. Duke-Elder and P. McFaul, “Orbital involvement in general diseases. I. Endocrine disorders, (Thyreotoxicosis and endocrine exophthalmos),” in System of Ophthalmology. The Ocular Adnexa, S. Duke-Elder, Ed., p. 935, Henry Kimpton, London, UK, 1974.
[23]
E. Sewall, “Operative control of progressive exophthalmos,” Archives of Otolaryngology, vol. 24, p. 621, 1936.
[24]
O. Hirsch, “Surgical decompression of exophthalmos,” Archives of Otolaryngology, vol. 51, p. 325, 1950.
[25]
T. E. Walsh and J. H. Ogura, “Transantral orbital decompression for malignant exophthalmos,” The Laryngoscope, vol. 67, no. 6, pp. 544–568, 1957.
[26]
L. Tallstedt, L. Lundblad, and A. ?ngg?rd, “Results of transantral orbital decompression in patients with thyroid- associated ophthalmopathy,” Acta Ophthalmologica Scandinavica, vol. 78, no. 2, pp. 206–210, 2000.
[27]
D. W. Kennedy, M. L. Goodstein, N. R. Miller, and S. J. Zinreich, “Endoscopic transnasal orbital decompression,” Archives of Otolaryngology, vol. 116, no. 3, pp. 275–282, 1990.
[28]
O. Michel, N. Oberl?nder, P. Neugebauer, A. Neugebauer, and W. Rü?mann, “Follow-up of transnasal orbital decompression in severe Graves' ophthalmopathy,” Ophthalmology, vol. 108, no. 2, pp. 400–404, 2001.
[29]
E. L. Chang, C. R. Bernardino, and P. A. D. Rubin, “Transcaruncular orbital decompression for management of compressive optic neuropathy in thyroid-related orbitopathy,” Plastic and Reconstructive Surgery, vol. 112, no. 3, pp. 739–747, 2003.
[30]
N. Shorr, H. I. Baylis, R. A. Goldberg, and J. D. Perry, “Transcaruncular approach to the medial orbit and orbital apex,” Ophthalmology, vol. 107, no. 8, pp. 1459–1463, 2000.
[31]
D. A. Paridaens, K. Verhoeff, D. Bouwens, and W. A. Van Den Bosch, “Transconjunctival orbital decompression in Graves' ophthalmopathy: lateral wall approach ab interno,” British Journal of Ophthalmology, vol. 84, no. 7, pp. 775–781, 2000.
[32]
C. D. McCord Jr., “Orbital decompression for Graves' disease. Exposure through lateral canthal and inferior fornix incision,” Ophthalmology, vol. 88, no. 6, pp. 533–541, 1981.
[33]
R. A. Goldberg, D. A. Weinberg, N. Shorr, and D. Wirta, “Maximal, three-wall, orbital decompression through a coronal approach,” Ophthalmic Surgery and Lasers, vol. 28, no. 10, pp. 832–843, 1997.
[34]
M. Mourits, L. Koornneef, W. M. Wiersinga, M. F. Prummel, A. Berghout, and R. Van Der Gaag, “Orbital decompression for Graves' ophthalmopathy by inferomedial, by inferomedial plus lateral, and by coronal approach,” Ophthalmology, vol. 97, no. 5, pp. 636–641, 1990.
[35]
K. G. H. Van der Wal, J. G. A. M. De Visscher, R. J. Boukes, and B. Smeding, “Surgical treatment of Graves orbitopathy: a modified balanced technique,” International Journal of Oral and Maxillofacial Surgery, vol. 30, no. 4, pp. 254–258, 2001.
[36]
I. V. Sasim, M. E. L. De Graaf, T. T. J. M. Berendschot, R. Kalmann, C. Van Isterdael, and M. P. Mourits, “Coronal or swinging eyelid decompression for patients with disfiguring proptosis in Graves' orbitopathy? Comparison of results in one center,” Ophthalmology, vol. 112, no. 7, pp. 1310–1315, 2005.
[37]
R. Kalmann, “Coronal approach for rehabilitative orbital decompression in Graves' ophthalmopathy,” British Journal of Ophthalmology, vol. 81, no. 1, pp. 41–45, 1997.
[38]
D. O. Kikkawa, K. Pornpanich, R. C. Cruz, L. Levi, and D. B. Granet, “Graded orbital decompression based on severity of proptosis,” Ophthalmology, vol. 109, no. 7, pp. 1219–1224, 2002.
[39]
L. Baldeschi, “Small versus coronal incision orbital decompression in graves' orbitopathy,” Orbit, vol. 28, no. 4, pp. 231–236, 2009.
[40]
L. Baldeschi, K. MacAndie, C. Hintschich, I. M. M. J. Wakelkamp, M. F. Prummel, and W. M. Wiersinga, “The removal of the deep lateral wall in orbital decompression: its contribution to exophthalmos reduction and influence on consecutive diplopia,” American Journal of Ophthalmology, vol. 140, no. 4, pp. 642–647, 2005.
[41]
K. L. Bailey, R. N. Tower, and R. A. Dailey, “Customized, single-incision, three-wall orbital decompression,” Ophthalmic Plastic and Reconstructive Surgery, vol. 21, no. 1, pp. 1–9, 2005.
[42]
R. A. Goldberg, J. D. Perry, V. Hortaleza, and J. T. Tong, “Strabismus after balanced medial plus lateral wall versus lateral wall only orbital decompression for dysthyroid orbitopathy,” Ophthalmic Plastic and Reconstructive Surgery, vol. 16, no. 4, pp. 271–277, 2000.
[43]
D. E. Siracuse-Lee and M. Kazim, “Orbital decompression: current concepts,” Current Opinion in Ophthalmology, vol. 13, no. 5, pp. 310–316, 2002.
[44]
R. A. Goldberg, A. J. Kim, and K. M. Kerivan, “The lacrimal keyhole, orbital door jamb, and basin of the inferior orbital fissure: three areas of deep bone in the lateral orbit,” Archives of Ophthalmology, vol. 116, no. 12, pp. 1618–1624, 1998.
[45]
R. A. Goldberg, “The evolving paradigm of orbital decompression surgery,” Archives of Ophthalmology, vol. 116, no. 1, pp. 95–96, 1998.
[46]
P. Mehta and O. M. Durrani, “Outcome of deep lateral wall rim-sparing orbital decompression in thyroid-associated orbitopathy: a new technique and results of a case series,” Orbit, vol. 30, no. 6, pp. 265–268, 2011.
[47]
R. A. Goldberg, A. E. Soroudi, and J. D. McCann, “Treatment of prominent eyes with orbital rim onlay implants: four-year experience,” Ophthalmic Plastic and Reconstructive Surgery, vol. 19, no. 1, pp. 38–45, 2003.
[48]
V. J. Lund, G. Larkin, P. Fells, and G. Adams, “Orbital decompression for thyroid eye disease: a comparison of external and endoscopic techniques,” Journal of Laryngology and Otology, vol. 111, no. 11, pp. 1051–1055, 1997.
[49]
R. Metson and M. Samaha, “Endoscopic orbital decompression,” in Manual of Endoscopic Lacrimal and Orbital Surgery, J. J. Woog, Ed., Butterworth-Heinemann, Philadelphia, Pa, USA, 2004.
[50]
R. Metson and M. Samaha, “Reduction of diplopia following endoscopic orbital decompression: the orbital sling technique,” Laryngoscope, vol. 112, no. 10, pp. 1753–1757, 2002.
[51]
M. P. Mourits, H. Bijl, M. A. Altea et al., “Outcome of orbital decompression for disfiguring proptosis in patients with Graves' orbitopathy using various surgical procedures,” British Journal of Ophthalmology, vol. 93, no. 11, pp. 1518–1523, 2009.
[52]
C. B. Terwee, M. N. Gerding, F. W. Dekker, M. F. Prummel, and W. M. Wiersinga, “Development of a disease specific quality of life questionnaire for patients with Graves' ophthalmopathy: the GO-QOL,” British Journal of Ophthalmology, vol. 82, no. 7, pp. 773–779, 1998.
[53]
M. J. Millar and A. J. Maloof, “The application of stereotactic navigation surgery to orbital decompression for thyroid-associated orbitopathy,” Eye, vol. 23, no. 7, pp. 1565–1571, 2009.
[54]
N. Olivari, “Transpalpebral decompression in Graves' disease,” Wiener Medizinische Wochenschrift, vol. 138, no. 18, pp. 452–455, 1988.
[55]
N. Olivari, “Transpalpebral decompression of endocrine ophthalmopathy (Graves' disease) by removal of intraorbital fat: experience with 147 operations over 5 years,” Plastic and Reconstructive Surgery, vol. 87, no. 4, pp. 627–641, 1991.
[56]
S. Trokel, M. Kazim, and S. Moore, “Orbital fat removal: decompression for Graves orbitopathy,” Ophthalmology, vol. 100, no. 5, pp. 674–682, 1993.
[57]
J. P. Adenis, P. Y. Robert, J. G. H. Lasudry, and Z. Dalloul, “Treatment of proptosis with fat removal orbital decompression in Graves' ophthalmopathy,” European Journal of Ophthalmology, vol. 8, no. 4, pp. 246–252, 1998.
[58]
J. P. Adenis, P. Camezind, P. Y. Robert et al., “Is incidence of diplopia after fat removal orbital decompression a predictive factor of choice of surgical technique for Graves' ophthalmopathy?” Bulletin de l'Academie Nationale de Medecine, vol. 187, no. 9, pp. 1649–1660, 2003.
[59]
B. S. Sires, B. N. Lemke, R. K. Dortzbach, and R. S. Gonnering, “Characterization of human orbital fat and connective tissue,” Ophthalmic Plastic and Reconstructive Surgery, vol. 14, no. 6, pp. 403–414, 1998.
[60]
J. L. Demer, J. M. Miller, and V. Poukens, “Surgical implications of the rectus extraocular muscle pulleys,” Journal of Pediatric Ophthalmology and Strabismus, vol. 33, no. 4, pp. 208–218, 1996.
[61]
Y. Inoue, T. Tsuboi, A. Kouzaki, T. Maeda, and T. Inoue, “Ophthalmic surgery in dysthyroid ophthalmopathy,” Thyroid, vol. 12, no. 3, pp. 257–263, 2002.
[62]
M. D. Abràmoff, R. Kalmann, M. E. L. De Graaf, J. S. Stilma, and M. P. Mourits, “Rectus extraocular muscle paths and decompression surgery for graves orbitopathy: mechanism of motility disturbances,” Investigative Ophthalmology and Visual Science, vol. 43, no. 2, pp. 300–307, 2002.
[63]
R. Metson, R. L. Dallow, and J. W. Shore, “Endoscopic orbital decompression,” Laryngoscope, vol. 104, no. 8, part 1, pp. 950–957, 1994.
[64]
E. A. Chu, N. R. Miller, and A. P. Lane, “Selective endoscopic decompression of the orbital apex for dysthyroid optic neuropathy,” Laryngoscope, vol. 119, no. 6, pp. 1236–1240, 2009.
[65]
N. Fichter, M. Schittkowski, V. Hingst, and R. F. Guthoff, “Graves' orbitopathy -radiological aspects after orbital decompression and correlation to clinical findings,” in Proceedings of the 24th meeting of the European Society of Ophthalmic Plastic and Reconstructive Surgery, London, UK, 2006.
[66]
G. J. Ben Simon, A. M. Syed, S. Lee et al., “Strabismus after deep lateral wall orbital decompression in thyroid-related orbitopathy patients using automated hess screen,” Ophthalmology, vol. 113, no. 6, pp. 1050–1055, 2006.
[67]
J. Esser and A. Eckstein, “Ocular muscle and eyelid surgery in thyroid-associated orbitopathy,” Experimental and Clinical Endocrinology and Diabetes, vol. 107, supplement 5, pp. S214–S221, 1999.
[68]
J. Esser, M. Schittkowski, and A. Eckstein, “Graves' orbitopaty: inferior rectus tendon elongation for large vertical squint angles that cannot be corrected by simple muscle recession,” Klinische Monatsbl?tter für Augenheilkunde, vol. 228, no. 10, pp. 880–886, 2011.
[69]
M. S. Ruttum, “Effect of prior orbital decompression on outcome of strabismus surgery in patients with thyroid ophthalmopathy,” Journal of AAPOS, vol. 4, no. 2, pp. 102–105, 2000.
[70]
G. Bonavolontà, “Postoperative blindness following orbital surgery,” Orbit, vol. 24, no. 3, pp. 195–200, 2005.
[71]
G. E. Rose, “The “devil's touch”; visual loss and orbital surgery. A synopsis of the Mustardé lecture, 2006,” Orbit, vol. 26, no. 3, pp. 147–158, 2007.
[72]
J. C. Long and G. D. Ellis, “Temporal decompression of the orbit for thyroid exophthalmos,” American Journal of Ophthalmology, vol. 62, no. 6, pp. 1089–1098, 1966.
[73]
C. R. Leone, K. L. Piest, and R. J. Newman, “Medial and lateral wall decompression for thyroid ophthalmopathy,” American Journal of Ophthalmology, vol. 108, no. 2, pp. 160–166, 1989.
[74]
H. D. Remulla, R. E. Gliklich, R. Metson, and P. A. D. Rubin, “Delayed orbital infection after endoscopic orbital decompression for dysthyroid orbitopathy,” Ophthalmology, vol. 107, no. 5, pp. 947–950, 2000.