Background. Population of elder Chinese has been increasing, but the pattern and trend of cancer in that population was rarely reported. Methods. Mortality rates for cancer of all sites and of the site specific of the overall and elderly Chinese from 2004 to 2005 were estimated. The age structure of world population was used to observe the changes in the age-standardized mortality rates from 1975 to 2005 using the data from the national death surveys, Disease Surveillance Points, and cancer registries in China. Results. The mortalities among the elderly Chinese were 782.12 per 100,000, substantially higher than those of the people less than 60 years old. The mortalities for cancers of lung, stomach, liver, and esophagus in elderly population showed great increase compared to younger ages. Stomach cancer ranked as the second most common cancer following lung cancer in the elderly, and those two malignancies had similar mortality rates in male elderly, while in female, it ranked as first, surpassed lung cancer. Consistent decreased trends of M/I ratios of cancer were observed in all age groups. Conclusion. Strategies in cancer prevention and cost-effective preventive intervention should be highly considered and strongly implemented among the elderly Chinese. 1. Introduction The recent national population survey showed that the elderly proportion has substantially increased in China in the last decades. In 2011, the number of Chinese in ages of 60 years and older reached at 177 million, up to 13.26% of the residents of mainland China, an increase of 2.93% compared to the same ages in 2000, according to the report of the National Statistics Bureau [1]. The health statistics of the Ministry of Health showed that malignant neoplasm ranked as first cause of deaths among both urban and rural residents of China in that time [2]. Lung cancer was the leading cancer cause of deaths in 2004-2005 resulted from rapid increasing of the mortality in the last thirty years [3–6]. However, there were few reports specifically on the patterns and the trends of cancer among the elderly Chinese, and the analyses were mainly limited for a city and county, or the cases in hospitals [7–9]. It is not clear for the characteristics of cancer in the elderly Chinese at national level. In the current paper, we analyzed the data from national death surveys, disease surveillance, and the cancer registry to describe the epidemiological characteristics and estimate the trends of cancer mortality in elderly Chinese. 2. Material and Methods 2.1. Definitions and Data Data used for analysis in
References
[1]
National Bureau of Statistics of China, “Bulletin of main data from sixth national population survey in 2010,” (No. 1), http://www.stats.gov.cn/tjgb/rkpcgb/qgrkpcgb/t20110428_402722232.htm.
[2]
Ministry of Health, Summary of Health Statistics in China 2012. Ministry of Health, http://www.moh.gov.cn/publicfiles/business/cmsresources/mohwsbwstjxxzx/cmsrsdocument/doc15055.pdf.
[3]
Z. Chen, Ed., The Third National Retrospective Sampling Death Survey Report, Peking Union Medical College Press, Beijing, China, 2008.
[4]
Office of Cancer Preventive and Control of Ministry of Health, Eds., The Study on Cancer Death Survey in Chinese Population, People's Health Press, Beijing, China, 1979.
[5]
Y. S. Zhou, Ed., Atlas of Mortality From Main Death Causes in China, School of Public Health, Tongji Medical University, China Cartographic Publishing, Beijing, China, 1990.
[6]
G. Yang, L. Kong, W. Zhao, et al., “Emergence of chronic non-communicable diseases in China,” The Lancet, vol. 372, pp. 1697–1705, 2008.
[7]
D. W. Liu, X. H. Tang, and H. Xu, “An analysis of the cancer-spectrum of the elderly in Chongqing from 1991 to 1998,” Chinese Journal of Geriatrics, vol. 20, pp. 294–296, 2001.
[8]
H. R. Zhao, P. Liu, and Y. X. Bao, “Analysis on 3748 cases of malignant tumors among elderly population in Xinjiang,” The Journal of Practical Medicine, vol. 27, pp. 2771–2773, 2011.
[9]
C. Huang and X. P. Chen, “Epidemiology and pre-treatment evaluation for cancer cases in old population,” Chinese Journal of Endocrine Surgery, vol. 3, pp. 265–287, 2009.
[10]
Depatrment of Disease Prevention, Control of Ministry of Health, and Chinese Academy of Prevention Medicine, “A series of Reports on Chinese Disease Surveillance,” 1995 Annual Report on Chinese Disease Surveillance 6, Beijing Medical University Press, 1997.
[11]
X. N. Zou, L. D. Li, and X. D. Dai, “Cancer incidence,” in Cancer Incidence and Mortality in Selected City/County in China, 1993–1997, National Office for Cancer Prevention, Control, and Center of Health Statistical Information of Ministry of Health, Eds., pp. 21–34, Chinese Medical Science and Technology Press, Beijing, China, 2002.
[12]
National Cancer Center, Disease Prevention, Control Bureau, and Ministry of Health, Eds., 2011 Chinese Cancer Registry Annual Report, Military Medical Science Press, Beijing, China, 2012.
[13]
L. D. Li, K. Q. Rao, S. W. Zhang, F. Z. Lu, and X. N. Zou, “Statistical analysis of data from 12 cancer registries in China, 1993–1997,” China Cancer Bulletin, vol. 11, pp. 497–507, 2001.
[14]
G. H. Yang, G. Zheng, X. W. Zheng, et al., “Selection of the second stage of DSP system and its representative,” Journal of Chinese Epidemiology, vol. 13, pp. 79–81, 1992.
[15]
C. Rao, G. Yang, J. Hu, J. Ma, W. Xia, and A. D. Lopez, “Validation of cause-of-death statistics in urban China,” International Journal of Epidemiology, vol. 36, no. 3, pp. 642–651, 2007.
[16]
L. Wang, G. Yang, J. Ma et al., “Evaluation of the quality of cause of death statistics in rural China using verbal autopsies,” Journal of Epidemiology and Community Health, vol. 61, no. 6, pp. 519–526, 2007.
[17]
G. Yang, C. Rao, J. Ma et al., “Validation of verbal autopsy procedures for adult deaths in China,” International Journal of Epidemiology, vol. 35, no. 3, pp. 741–748, 2006.
[18]
P. W. Setel, C. Rao, Y. Hemed et al., “Core verbal autopsy procedures with comparative validation results from two countries,” PLoS Medicine, vol. 3, no. 8, pp. 1282–1291, 2006.
[19]
C. Rao, A. D. Lopez, G. Yang, S. Begg, and J. Ma, “Evaluating national cause-of-death statistics: principles and application to the case of China,” Bulletin of the World Health Organization, vol. 83, no. 8, pp. 618–625, 2005.
[20]
O. B. Ahmad, C. B. Pinto, A. D. Lopez, et al., “Age standardization of rates: a new WHO standard,” GPE Discussion Paper Series 31, World Health Organization, Geneva, Switzerland, 2001.
[21]
G. H. Yang, Deaths and Their Risk Factors Among Chinese Populationpp, Chinese Union Medical University Press, Beijing, China, 2005.
[22]
T. Lei, W. M. Mao, H. J. Yang et al., “Study on cancer incidence through the cancer registry program in 11 cities and countries, China,” Chinese Journal of Epidemiology, vol. 30, pp. 1165–1170, 2009.
[23]
W. Q. Chen, S. W. Zhang, L. D. Li et al., “An analysis of lung cancer incidence and mortality from 30 cancer registries in China, 1998–2002,” China Cancer Bulletin, vol. 15, pp. 570–574, 2006.
[24]
W. Q. Chen, R. S. Zheng, S. W. Zhang, N. Wang, L. Yang, and J. He, “An analysis of lung cancer incidence and mortality in China, 2003–2007,” Practical Oncology Journal, vol. 26, pp. 6–10, 2012.
[25]
“Tobacco use,” in Global Adult Tobacco Survey (GATS) China 2010 Country Report, G. H. Yang, Ed., pp. 8–13, Chinese Three Gorge Press, Beijing, China, 2011.
[26]
X. N. Zou, J. M. Jiang, B. Q. Liu et al., “Study on the relations between smoking and the risk of age-specific lung cancer deaths in urban and rural areas of China,” Chinese Journal of Epidemiology, vol. 30, no. 9, pp. 907–910, 2009.
[27]
X. N. Zou, X. B. Sun, W. Q. Chen et al., “Analysis of incidence and mortality of stomach cancer in China from 2003 to 2007,” Tumor, vol. 32, pp. 109–114, 2012.
[28]
A. Jemal, M. M. Center, C. DeSantis, and E. M. Ward, “Global patterns of cancer incidence and mortality rates and trends,” Cancer Epidemiology Biomarkers and Prevention, vol. 19, no. 8, pp. 1893–1907, 2010.