Subjects and Methods. We analysed 5000 cerebrovascular ultrasound records. A total of 0.4% of the patients had common carotid artery occlusion (CCAO). Results. The mean age was years, and the male/female ratio was 2.33. The most frequent risk factors were hypertension, ischaemic heart disease, dyslipidemia, diabetes mellitus, and smoking. Right-sided and left-sided CCAO occurred in 65% and 30% of the cases, respectively, and bilateral occlusion was detected in one case (5%). Patent bifurcation was observed in 10 cases of CCAO in which the anterograde flow in the ICA was maintained from the external carotid artery with reversed flow. In two of the cases, the occluded CCA was hypoplastic. The aetiology of CCAO in the majority of cases was the atherosclerosis (15 cases). The male/female ratio was higher in the patients with occluded distal vessels, and the short-term outcome was poorer. Only two cases from this series underwent revascularisation surgery. Spontaneous recanalisation was observed in one case. Conclusions. The most frequent cause of CCAO was atherosclerosis. The outcome is improved in the cases with patent distal vessels, and spontaneous recanalisation is possible. Treatment methods have not been standardised. Surgical revascularisation is possible in cases of patent distal vessels, but the indications are debatable. 1. Introduction Common carotid artery (CCA) occlusion is a rare cause of cerebrovascular events. The prevalence is approximately 0.24–5% in stroke patients [1–6]. In contrast to the large amount of data in the literature about internal carotid artery occlusion, there is little information regarding the incidence, clinical presentation, ultrasound findings, haemodynamics, causes, and treatment of common carotid artery occlusion (CCAO). CCA occlusion is generally associated with occlusion of the distal vessels (internal carotid artery (ICAs) and external carotid artery (ECA)). In some cases, blood flow in the ICA and ECA is maintained by collateral circulation via extracranial branches through the retrograde external carotid artery. Recognising the patency of the distal vessels is important because it may allow for effective surgical revascularisation [5]. Doppler ultrasound examination is an important tool in the diagnosis of CCAO. The aim of this study was to discuss the clinical findings, ultrasonographic characteristics, possible mechanisms, and treatment possibilities of common carotid artery occlusion. 2. Subjects and Methods We analysed 5000 duplex cerebrovascular ultrasound records performed during a 5-year period from 2008
References
[1]
A. N. Mónica, A. Germano, L. Biscoito, and M. Baptista, “Common carotid artery occlusion: doppler ultrasound findings in two patients,” Journal of Diagnostic Medical Sonography, vol. 21, no. 6, pp. 502–508, 2005.
[2]
Y.-J. Chang, S.-K. Lin, S.-J. Ryu, and Y.-Y. Wai, “Common carotid artery occlusion: evaluation with duplex sonography,” American Journal of Neuroradiology, vol. 16, no. 5, pp. 1099–1105, 1995.
[3]
R. Pretre, A. Kalangos, M. Bednarkiewicz, I. Bruschweiler, and B. Faidutti, “Reversed flow in the internal carotid artery after occlusion of the common carotid artery,” Thoracic and Cardiovascular Surgeon, vol. 42, no. 6, pp. 358–360, 1994.
[4]
T. S. Riles, A. M. Imparato, M. P. Posner, and B. C. Eikelboom, “Common carotid occlusion. Assessment of the distal vessels,” Annals of Surgery, vol. 199, no. 3, pp. 363–366, 1984.
[5]
M. Belkin, W. C. Mackey, M. S. Pessin, L. R. Caplan, T. F. O'Donnell, and D. B. Pilcher, “Common carotid artery occlusion with patent internal and external carotid arteries: diagnosis and surgical management,” Journal of Vascular Surgery, vol. 17, no. 6, pp. 1019–1028, 1993.
[6]
C.-F. Tsai, J.-S. Jeng, C.-J. Lu, and P.-K. Yip, “Clinical and ultrasonographic manifestations in major causes of common carotid artery occlusion,” Journal of Neuroimaging, vol. 15, no. 1, pp. 50–56, 2005.
[7]
W. P. Arend, B. A. Michel, D. A. Bloch et al., “The American College of Rheumatology 1990 criteria for the classification of Takayasu arteritis,” Arthritis and Rheumatism, vol. 33, no. 8, pp. 1129–1134, 1990.
[8]
T. Baumann, A. J. Steck, and P. Lyrer, “Aetiologies, clinical and vascular findings in symptomatic and asymptomatic carotid artery occlusion,” Schweizer Archiv für Neurologie und Psychiatrie, vol. 153, no. 7, pp. 316–320, 2002.
[9]
P. Lyden, M. Lu, C. Jackson et al., “Underlying structure of the National Institutes of Health stroke scale: results of a factor analysis,” Stroke, vol. 30, no. 11, pp. 2347–2354, 1999.
[10]
B. Jennett and M. Bond, “Assessment of outcome after severe brain damage. A practical scale,” Lancet, vol. I, no. 7905, pp. 480–484, 1975.
[11]
D. G. Parthenis, D. G. Kardoulas, C. V. Ioannou et al., “TTotal occlusion of the common carotid artery: a modified classification and its relation to clinical status,” Ultrasound in Medicine and Biology, vol. 34, no. 6, pp. 867–873, 2008.
[12]
W. K. Hass, W. S. Fields, R. R. North, I. I. Kircheff, N. E. Chase, and R. B. Bauer, “Joint study of extracranial arterial occlusion. II. Arteriography, techniques, sites, and complications,” Journal of the American Medical Association, vol. 203, no. 11, pp. 961–968, 1968.
[13]
M. Collice, V. D'Angelo, and O. Arena, “Surgical treatment of common carotid artery occlusion,” Neurosurgery, vol. 12, no. 5, pp. 515–524, 1983.
[14]
P. C. Podore, C. G. Rob, J. A. De Weese, and R. M. Green, “Chronic common carotid occlusion,” Stroke, vol. 12, no. 1, pp. 98–100, 1981.
[15]
J. M. Valdueza, S. J. Schreiber, J. E. Roehl, and R. Klingebiel, Neurosonology and Neuroimaging of Stroke, Thieme, Stuttgart, Germany, 2008.
[16]
H. J. M. Barnett, S. J. Peerless, and J. C. E. Kaufmann, “‘Stump’ of internal carotid artery—a source for further cerebral embolic ischemia,” Stroke, vol. 9, no. 5, pp. 448–456, 1978.
[17]
H. M. Keller, A. Valavanis, H. G. Imhof, and M. Turina, “Patency of external and internal carotid artery in the presence of an occluded common carotid artery: noninvasive evaluation with combined cerebrovascular Doppler examination and sequential computertomography,” Stroke, vol. 15, no. 1, pp. 149–157, 1984.
[18]
J. Li, D. Shi, Y. Wei, J. Xiao, K. Zhang, and M. Wang, “Blood flow in the internal carotid artery with common carotid artery-occluding lesions in Takayasu arteritis,” Journal of Ultrasound in Medicine, vol. 29, no. 11, pp. 1547–1553, 2010.
[19]
S.-L. Lai, Y.-C. Chen, H.-H. Weng, S.-T. Chen, S.-P. Hsu, and T.-H. Lee, “Bilateral common carotid artery occlusion—a case report and literature review,” Journal of the Neurological Sciences, vol. 238, no. 1-2, pp. 101–104, 2005.
[20]
S. R. Levine and K. M. A. Welch, “Common carotid artery occlusion,” Neurology, vol. 39, no. 2 I, pp. 178–186, 1989.
[21]
V. Zbornikova and C. Lassvik, “Common carotid artery occlusion: haemodynamic features duplex and transcranial doppler assessment and clinical correlation,” Cerebrovascular Diseases, vol. 1, pp. 136–141, 1991.
[22]
D. L. Cull, J. C. Hansen, S. M. Taylor, E. M. Langan III, B. A. Snyder, and C. B. Coffey, “Internal carotid artery patency following common carotid artery occlusion: management of the asymptomatic patient,” Annals of Vascular Surgery, vol. 13, no. 1, pp. 73–76, 1999.
[23]
N. Y. Verbeeck and C. Vazquez Rodriguez, “Patent internal and external carotid arteries beyond an occluded common carotid artery: report of a case diagnosed by color Doppler,” Journal Belge de Radiologie, vol. 82, no. 5, pp. 219–221, 1999.
[24]
Z. Bajko, R. Balasa, S. Petrutiu, L. Toma, S. Russu, and I. Pascu, “Mobile carotid artery thrombus,” Romanian Journal of Neurology, vol. 8, no. 4, pp. 184–186, 2009.
[25]
Q. A. Shah, “Spontaneous recanalization after complete occlusion of the common carotid artery with subsequent embolic ischemic stroke,” Journal of Vascular and Interventional Neurology, vol. 2, pp. 147–151, 2009.
[26]
R. S. Martin III, W. H. Edwards, J. L. Mulherin Jr., and W. H. Edwards Jr., “Surgical treatment of common carotid artery occlusion,” The American Journal of Surgery, vol. 165, no. 3, pp. 302–306, 1993.
[27]
L. Pintér, C. Cagiannos, C. N. Bakoyiannis, and R. Kolvenbach, “Hybrid treatment of common carotid artery occlusion with ring-stripper endarterectomy plus stenting,” Journal of Vascular Surgery, vol. 46, no. 1, pp. 135–139, 2007.
[28]
V. K. Sharma, G. Tsivgoulis, A. Y. Lao et al., “Thrombotic occlusion of the common carotid artery (CCA) in acute ischemic stroke treated with intravenous tissue plasminogen activator (TPA),” European Journal of Neurology, vol. 14, no. 2, pp. 237–240, 2007.
[29]
W. J. Powers, “Management of patients with atherosclerotic carotid occlusion,” Current Treatment Options in Neurology, vol. 13, no. 6, pp. 608–615, 2011.