Standardized family-based interventions are the most effective way of preventing or treating adolescent substance abuse and delinquency. This paper first reviews the incidence of adolescent substance abuse worldwide emphasizing gender and causes by etiological risk and protective factors. New epigenetic research is included suggesting that nurturing parenting significantly prevents the phenotypic expression of inherited genetic diseases including substance abuse. Evidence-based family interventions are reviewed including family change theories behind their success, principles and types of family-based interventions, research results, cultural adaptation steps for ethnic and international translation, and dissemination issues. The author’s Strengthening Family Program is used as an example of how these principles of effective prevention and cultural adaptation can result in highly effective prevention programs not only for substance abuse, but for other impulse control disorders as well. The conclusions include recommendations for more use of computer technologies to cut the high cost of family interventions relative to youth-only prevention programs and increase the public health impact of evidence-based prevention programs. The paper recommends that to reduce health care costs these family-based approaches should be applied to the prevention and treatment of other impulse control disorders such as obesity and type 2 diabetes, sexually transmitted diseases, and delinquency. 1. Introduction Adolescent behavioural health problems are on the rise worldwide particularly for impulse control disorders (ICDs) including substance abuse, delinquency, obesity, delinquency, and HIV/STDs. Contributing to these developmental issues are children growing up in homes of substance abusing, depressed, highly stressed, and dysfunctional parents. Unfortunately, even functional parents are spending less time with their children because of the worldwide economic crisis that has parents working more hours. Even simple things such as the diminishing number of family meals eaten together have been found to have a negative impact on later adolescent’s risk for substance use and negative youth development [1]. When parents and extended family members cannot spend much time parenting their children, they have to get more efficient with the little parenting time they have available if they want their children to grow up to be healthy and productive adults. Hence, disseminating effective parenting and family skills training practices more widely could buffer against the current
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