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NonHodgkin's Lymphoma with Peritoneal Localization

DOI: 10.1155/2014/723473

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Abstract:

The gastrointestinal tract is the most common extranodal site involved with lymphoma accounting for 5–20% of all cases. Lymphoma can occur at any site of the body, but diffuse and extensive involvement of the peritoneal cavity is unusual and rare. We report a case of diffuse large B-cell lymphoma in a 57-year-old female infiltrating the peritoneum and omentum and presenting with ascites and pleural effusion. The performed examinations did not discover any pathological findings affecting the digestive tract or parenchymal organs, except for diffuse thickening of the peritoneum and omentum. Peripheral, mediastinal, or retroperitoneal lymphadenopathy was not registered. The blood count revealed only elevated leukocytes and on examination there were no immature blood cells in the peripheral blood. The cytology from the ascites and pleural effusion did not detect any malignant cells. Due to the rapid disease progression the patient died after twenty-two days of admission. The diagnosis was discovered postmortem with the histological examination and immunohistochemical study of the material taken during the surgical laparoscopy performed four days before the lethal outcome. Although cytology is diagnostic in most cases, laparoscopy with peritoneal biopsy is the only procedure which can establish the definitive diagnosis of peritoneal lymphomatosis. 1. Introduction Extranodal lymphoma occurs in about 40% of all patients with lymphoma and has been described in virtually every organ and tissue [1]. Extranodal disease is more common with nonHodgkin’s lymphoma (NHL); it is often intermediate- to high-grade [2, 3] and the extranodal involvement is in general a poor prognostic factor [4]. Secondary involvement of extranodal tissue as part of generalized lymphoma is significantly more common than primary extranodal disease in which there is a dominant extranodal component with no or minor nodal involvement [4]. The gastrointestinal tract is the most common extranodal site involved with lymphoma accounting for 5–20% of all cases and a gastrointestinal involvement is usually secondary to widespread nodal disease [5]. Diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma are the dominant histological subtypes in extranodal lymphoma [4]. Although primary gastrointestinal lymphomas (PGLs) are relatively rare, they are still the most common type of primary extranodal lymphomas. PGL accounts for 40% of all extranodal NHLs, for 4%–20% of all NHL cases, and for about 1%–4% of all gastrointestinal malignancies [4, 6–9]. Almost 90% of the PGLs are of B cell lineage and

References

[1]  U. Metser, O. Goor, H. Lerman, E. Naparstek, and E. Even-Sapir, “PET-CT of extranodal lymphoma,” American Journal of Roentgenology, vol. 182, no. 6, pp. 1579–1586, 2004.
[2]  S. J. Vinnicombe and R. H. Reznek, “Extranodal manifestations of lymphoma,” Imaging, vol. 11, no. 4, pp. 240–268, 1999.
[3]  A. Guermazi, P. Brice, E. de Kerviler et al., “Extranodal Hodgkin disease: spectrum of disease,” RadioGraphics, vol. 21, no. 1, pp. 161–179, 2001.
[4]  W. K. Lee, E. W. Lau, V. A. Duddalwar, A. J. Stanley, and Y. Y. Ho, “Abdominal manifestations of extranodal lymphoma: spectrum of imaging findings,” American Journal of Roentgenology, vol. 191, no. 1, pp. 198–206, 2008.
[5]  C. Freeman, J. W. Berg, and S. J. Cutler, “Occurrence and prognosis of extranodal lymphomas,” Cancer, vol. 29, no. 1, pp. 252–260, 1972.
[6]  F. D'amore, H. Brincker, K. Gronbaek et al., “Non-Hodgkin's lymphoma of the gastrointestinal tract: a population-based analysis of incidence, geographic distribution, clinicopathologic presentation features, and prognosis,” Journal of Clinical Oncology, vol. 12, no. 8, pp. 1673–1684, 1994.
[7]  J. Morton, M. Leyland, G. Hudson et al., “Primary gastrointestinal non-Hodgkin's lymphoma: a review of 175 British national lymphoma investigation cases,” British Journal of Cancer, vol. 67, no. 4, pp. 776–782, 1992.
[8]  R. Oter, R. Bieger, P. Kluin, J. Hermans, and R. Willemze, “Primary gastrointestinal non-Hodkin's lymphoma in a population-based registry,” British Journal of Cancer, vol. 60, no. 5, pp. 745–750, 1989.
[9]  P. Franco, A. R. Filippi, P. Ciammella et al., “Primary duodenal follicular lymphoma: 6-years complete remission after combined radio-immunotherapy,” Acta Gastro Enterologica Belgica, vol. 74, no. 2, pp. 337–342, 2011.
[10]  P. Ghimire, G. Y. Wu, and L. Zhu, “Primary gastrointestinal lymphoma,” World Journal of Gastroenterology, vol. 17, no. 6, pp. 697–707, 2011.
[11]  R. Herrmann, A. M. Panahon, M. P. Barcos, D. Walsh, and L. Stutzman, “Gastrointestinal involvement in non-Hodgkin's lymphoma,” Cancer, vol. 46, no. 1, pp. 215–222, 1980.
[12]  S. H. Swerdlow, E. Campo, N. L. Harris, et al., Eds., World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues, IARC Press, Lyon, France, 2008.
[13]  L. M. Morton, S. S. Wang, S. S. Devesa, P. Hartge, D. D. Weisenburger, and M. S. Linet, “Lymphoma incidence patterns by WHO subtype in the United States, 1992–2001,” Blood, vol. 107, no. 1, pp. 265–276, 2006.
[14]  M. B. Moller, N. T. Pedersen, and B. E. Christensen, “Diffuse large B-cell lymphoma: clinical implications of extranodal versus nodal presentation—a population-based study of 1575 cases,” British Journal of Haematology, vol. 124, no. 2, pp. 151–159, 2004.
[15]  J. O. Armitage, P. M. Mauch, N. L. Harris, and B. P. Lymphomas, “Non-Hodgkin’s lymphomas,” in Cancer:Principles and Practice of Oncology, V. T. de Vita Jr., Ed., pp. 2256–2316, Lippincott Williams & Wilkins, Philadelphia, Pa, USA, 2001.
[16]  F. d'amore, B. E. Christensen, H. Brincker et al., “Clinicopathological features and prognostic factors in extranodal non-Hodgkin lymphomas,” European Journal of Cancer, vol. 27, no. 10, pp. 1201–1208, 1991.
[17]  U. Mey, F. Hitz, A. Lohri et al., “Diagnosis and treatment of diffuse large B-cell lymphoma,” Swiss Medical Weekly, vol. 142, Article ID w13511, 2012.
[18]  Y. Chen, T. Han, J. Iqbal et al., “Diffuse large B-cell lymphoma in Chinese patients: immunophenotypic and cytogenetic analyses of 124 cases,” American Journal of Clinical Pathology, vol. 133, no. 2, pp. 305–313, 2010.
[19]  E. Campo, S. H. Swerdlow, N. L. Harris, S. Pileri, H. Stein, and E. S. Jaffe, “The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications,” Blood, vol. 117, no. 19, pp. 5019–5032, 2011.
[20]  J. J. Turner, A. M. Hughes, A. Kricker et al., “WHO non-Hodgkin's lymphoma classification by criterion-based report review followed by targeted pathology review: an effective strategy for epidemiology studies,” Cancer Epidemiology Biomarkers and Prevention, vol. 14, no. 9, pp. 2213–2219, 2005.
[21]  Y. L. Yang, J. Wang, L. Z. Zhao, Z. F. Gao, H. M. Jing, and X. Y. Ke, “Clinical characteristics, cell origin and prognosis of primary gastrointestinal diffuse large B-cell lymphoma: a report of 40 cases,” Ai Zheng, vol. 27, no. 6, pp. 636–641, 2008.
[22]  A. M. Perry, Z. Mitrovic, and W. C. Chan, “Biological prognostic markers in diffuse large B-cell lymphoma,” Cancer Control, vol. 19, no. 3, pp. 214–226, 2012.
[23]  R. I. Fisher, T. P. Miller, and O. A. O'connor, “Diffuse aggressive lymphoma,” Hematology, pp. 221–236, 2004.
[24]  S. C. Weng and C. Y. Wu, “Lymphoma presenting as peritoneal lymphomatosis with ascites,” Journal of the Chinese Medical Association, vol. 71, no. 12, pp. 646–650, 2008.
[25]  B. A. Runyon and J. C. Hoefs, “Peritoneal lymphomatosis with ascites: a characterization,” Archives of Internal Medicine, vol. 146, no. 5, pp. 887–888, 1986.
[26]  M. A. Lynch, K. C. Cho, R. B. Jeffrey Jr., D. D. Alterman, and M. P. Federle, “CT of peritoneal lymphomatosis,” American Journal of Roentgenology, vol. 151, no. 4, pp. 713–715, 1988.
[27]  D. L. Angela, C. S. Janet, and H. S. Mcleslie, “Secondary tumors and tumor like lesions of the peritoneal cavity: imaging features with pathologic correlation,” RadioGraphics, vol. 29, no. 2, pp. 347–373, 2009.
[28]  Y. G. Kim, J. Y. Baek, S. Y. Kim et al., “Peritoneal lymphomatosis confounded by prior history of colon cancer: a case report,” BMC Cancer, vol. 11, article 276, 2011.
[29]  M. Horger, M. Muller-Schimpfle, I. Yirkin, M. Wehrmann, and C. D. Claussen, “Extensive peritoneal and omental lymphomatosis with raised CA 125 mimicking carcinomatosis: CT and intraoperative findings,” British Journal of Radiology, vol. 77, no. 913, pp. 71–73, 2004.
[30]  M. P. Ridolfini, P. Caprino, S. Berardi et al., “A very advanced case of a T cell peritoneal lymphomatosis,” Annali Italiani di Chirurgia, vol. 83, no. 1, pp. 71–73, 2012.
[31]  M. B. Aslam, “Peritoneal lymphomatosis, a morphological look alike to peritoneal carcinomatosis: an autopsy report,” Journal of Clinical Pathology, vol. 62, no. 5, article 480, 2009.
[32]  N. Hazarika, B. Dhabhar, and T. K. Saikia, “Highly elevated serum CA 125 in a lady with ascites and retroperitoneal mass—a diagnostic dilemma,” Journal of Association of Physicians of India, vol. 56, pp. 47–48, 2008.
[33]  M. I. Sharifah, N. A. Zamzami, and T. N. Rafeah, “Diffuse peritoneal lymphomatosis simulating peritoneal carcinomatosis,” Medical Journal of Malaysia, vol. 66, no. 3, pp. 270–272, 2011.
[34]  J. E. Jacobs, K. E. Salhany, K. R. Fox, and B. A. Birnbaum, “Omental caking in Hodgkin's disease. Computed tomography findings,” Clinical Imaging, vol. 20, no. 4, pp. 253–255, 1996.
[35]  P. Goodman and B. Raval, “Omental cakes in American Burkitt lymphoma: computed tomography demonstration,” Clinical Imaging, vol. 13, no. 2, pp. 117–118, 1989.
[36]  Y. Kim, O. Cho, S. Song, H. Lee, H. Rhim, and B. Koh, “Peritoneal lymphomatosis: CT findings,” Abdominal Imaging, vol. 23, no. 1, pp. 87–90, 1998.
[37]  Y. Tsutsumi, K. I. Inada, K. Morita, and T. Suzuki, “T-cell lymphomas diffusely involving the intestine: report of two rare cases,” Japanese Journal of Clinical Oncology, vol. 26, no. 4, pp. 264–272, 1996.
[38]  Y. N. Lin, J. W. Chou, P. H. Chuang, K. S. Cheng, C. Y. Peng, and I. P. Chiang, “Primary small intestinal natural killer/T cell lymphoma mimicking tuberculous peritonitis: report of a case and review of the literature,” Internal Medicine, vol. 50, no. 5, pp. 515–518, 2011.
[39]  G. Fasola, R. Fanin, F. Gherlinzoni, et al., “Serum LDH concentration in non-Hodgkin's lymphomas. Relationship to histologic type, tumor mass, and presentation features,” Acta Haematologica, vol. 72, no. 4, pp. 231–238, 1984.
[40]  O. Bairey, D. Blickstein, P. Stark et al., “Serum CA 125 as a prognostic factor in non-Hodgkin's lymphoma,” Leukemia & Lymphoma, vol. 44, no. 10, pp. 1733–1738, 2003.
[41]  B. W. Mol, N. Bayram, J. G. Lijmer et al., “The performance of CA-125 measurement in the detection of endometriosis: a meta-analysis,” Fertility and Sterility, vol. 70, no. 6, pp. 1101–1108, 1998.
[42]  E. Zuckerman, A. Lanir, E. Sabo et al., “Cancer antigen 125: a sensitive marker of ascites in patients with liver cirrhosis,” American Journal of Gastroenterology, vol. 94, no. 6, pp. 1613–1618, 1999.
[43]  H. Devarbhavi, D. Kaese, A. W. Williams, J. Rakela, G. G. Klee, and P. S. Kamath, “Cancer antigen 125 in patients with chronic liver disease,” Mayo Clinic Proceedings, vol. 77, no. 6, pp. 538–541, 2002.
[44]  K. Sj?vall, B. Nilsson, and N. Einhorn, “The significance of serum CA 125 elevation in malignant and nonmalignant diseases,” Gynecologic Oncology, vol. 85, no. 1, pp. 175–178, 2002.
[45]  O. Topalak, U. Saygili, M. Soyturk et al., “Serum, pleural effusion, and ascites CA-125 levels in ovarian cancer and nonovarian benign and malignant diseases: a comparative study,” Gynecologic Oncology, vol. 85, no. 1, pp. 108–113, 2002.
[46]  J. Zidan, O. Hussein, W. Basher, and S. Zohar, “Serum CA125: a tumor marker for monitoring response to treatment and follow-up in patients with non-Hodgkin's lymphoma,” The Oncologist, vol. 9, no. 4, pp. 417–421, 2004.
[47]  L. Benboubker, “A new serologic index for low-grade non-Hodgkin's lymphoma based on initial CA125 and LDH serum levels,” Annals of Oncology, vol. 11, no. 11, pp. 1485–1491, 2000.
[48]  M. Lazzarino, “Serum CA 125 is of clinical value in the staging and follow up of patient with non-Hodgkin’s lymphoma,” Cancer, vol. 82, pp. 576–582, 2000.
[49]  C. Bonnet, Y. Beguin, F. Fassotte, L. Seidel, F. Luyckx, and G. Fillet, “Limited usefulness of CA125 measurement in the management of Hodgkin's and non-Hodgkin's lymphoma,” European Journal of Haematology, vol. 78, no. 5, pp. 399–404, 2007.
[50]  I. D. Zacharos, S. P. Efstathiou, E. Petreli et al., “The prognostic significance of CA 125 in patients with non-Hodgkin's lymphoma,” European Journal of Haematology, vol. 69, no. 4, pp. 221–226, 2002.
[51]  A. Riquelme, M. Calvo, F. Salech et al., “Value of adenosine deaminase (ADA) in ascitic fluid for the diagnosis of tuberculous peritonitis: a meta-analysis,” Journal of Clinical Gastroenterology, vol. 40, no. 8, pp. 705–710, 2006.
[52]  R. Laniado-Laborin, “Adenosine deaminase in the diagnosis of tuberculous pleural effusion: is it really an ideal test? A word of caution,” Chest, vol. 127, no. 2, pp. 417–418, 2005.
[53]  M. Buyukberber, A. Sevinc, C. E. Cagliyan, M. T. Gulsen, I. Sari, and C. Camci, “Non-Hodgkin lymphoma with high adenosine deaminase levels mimicking peritoneal tuberculosis: an unusual presentation,” Leukemia & Lymphoma, vol. 47, no. 3, pp. 565–568, 2006.
[54]  Y. Ogat, K. Aoe, A. Hiraki et al., “Is adenosine deaminase in pleural fluid a useful marker for differentiating tuberculosis from lung cancer or mesothelioma in Japan, a country with intermediate incidence of tuberculosis?” Acta Medica Okayama, vol. 65, no. 4, pp. 259–263, 2011.
[55]  D. Schottenfeld, J. L. Beebe-Dimmer, and F. D. Vigneau, “The epidemiology and pathogenesis of neoplasia in the small intestine,” Annals of Epidemiology, vol. 19, no. 1, pp. 58–69, 2009.
[56]  M. S. Levine, S. E. Rubesin, L. Pantongrag-Brown, J. L. Buck, and H. Herlinger, “Non-Hodgkin's lymphoma of the gastrointestinal tract: radiographic findings,” American Journal of Roentgenology, vol. 168, no. 1, pp. 165–172, 1997.
[57]  E. J. Balthazar, M. Noordhoorn, A. J. Megibow, and R. B. Gordon, “CT of small-bowel lymphoma in immunocompetent patients and patients with AIDS: comparison of findings,” American Journal of Roentgenology, vol. 168, no. 3, pp. 675–680, 1997.
[58]  S. Ghai, J. Pattison, S. Ghai, M. E. O'Malley, K. Khalili, and M. Stephens, “Primary gastrointestinal lymphoma: spectrum of imaging findings with pathologic correlation,” RadioGraphics, vol. 27, no. 5, pp. 1371–1388, 2007.
[59]  B. Li, Y. K. Shi, X. H. He et al., “Primary non-Hodgkin lymphomas in the small and large intestine: clinicopathological characteristics and management of 40 patients,” International Journal of Hematology, vol. 87, no. 4, pp. 375–381, 2008.
[60]  J. C. Gonzalez-Vitale, L. G. Gomez, and R. M. Goldblum, “Immunoblastic lymphoma of small intestine complicating late-onset immunodeficiency,” Cancer, vol. 49, no. 3, pp. 445–449, 1982.
[61]  G. Stanojevi?, M. Stojanovi?, M. Jovanovi? et al., “Primary colorectal lymphomas,” Vojnosanitetski Pregled, vol. 66, no. 4, pp. 295–301, 2009.
[62]  S. Cai, F. Cannizzo Jr., K. M. Bullard Dunn, J. F. Gibbs, M. Czuczman, and A. Rajput, “The role of surgical intervention in non-Hodgkin's lymphoma of the colon and rectum,” American Journal of Surgery, vol. 193, no. 3, pp. 409–412, 2007.
[63]  O. Bairey, R. Ruchlemer, and O. Shpilberg, “Non-Hodgkin's lymphomas of the colon,” Israel Medical Association Journal, vol. 8, no. 12, pp. 832–835, 2006.
[64]  G. Z. Stanojevi?, M. P. Stojanovi?, M. M. Stojanovi? et al., “Non-Hodgkin’s lymphomas of the large bowel-clinical characteristics, prognostic factors and survival,” Acta Chirurgica Iugoslavica, vol. 55, pp. 109–114, 2008.
[65]  C. W. Fan, C. R. Changchien, J. Y. Wang et al., “Primary colorectal lymphoma,” Diseases of the Colon and Rectum, vol. 43, no. 9, pp. 1277–1282, 2000.
[66]  P. M. Banks and R. A. Warnke, “Primary effusion lymphoma,” in Tumours of Haematopoietic and Lymphoid Tissues: World Health Organization Classification of Tumours, E. S. Jaffe, N. L. Harris, H. Stein, and J. W. Vardium, Eds., pp. 179–180, IARC Press, Lyon, France, 2001.
[67]  A. Carbone and A. Gloghini, “PEL and HHV8-unrelated effusion lymphomas : classification and diagnosis,” Cancer, vol. 114, no. 4, pp. 225–227, 2008.
[68]  Y. B. Chen, A. Rahemtullah, and E. Hochberg, “Primary effusion lymphoma,” Oncologist, vol. 12, no. 5, pp. 569–576, 2007.
[69]  R. G. Nador, E. Cesarman, A. Chadburn et al., “Primary effusion lymphoma: a distinct clinicopathologic entity associated with the Kaposi's sarcoma-associated herpes virus,” Blood, vol. 88, no. 2, pp. 645–656, 1996.
[70]  D. S. Karcher and S. Alkan, “Human herpesvirus-8-associated body cavity-based lymphoma in human immunodeficiency virus-infected patients: a unique B-cell neoplasm,” Human Pathology, vol. 28, no. 7, pp. 801–808, 1997.
[71]  S. Morassut, E. Vaccher, L. Balestreri et al., “HIV-associated human herpesvirus 8-positive primary lymphomatous effusions: radiologic findings in six patients,” Radiology, vol. 205, no. 2, pp. 459–463, 1997.
[72]  E. Boulanger, L. Gerard, J. Gabarre et al., “Prognostic factors and outcome of human herpesvirus 8-associated primary effusion lymphoma in patients with AIDS,” Journal of Clinical Oncology, vol. 23, no. 19, pp. 4372–4380, 2005.

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