Rheumatoid arthritis (RA) is a systemic inflammatory, slowly progressive disease that results in cartilage and bone destruction. Temporomandibular joint (TMJ) involvement is not uncommon in RA, and it is present in about more than 50% of patients; however, TMJ is usually among the last joints to be involved and is associated with many varied clinical signs and symptoms. Hence, RA of TMJ presents to the dentist with great diagnostic challenges. This report presents a case of RA with bilateral TMJ involvement with its classical radiographic findings and review literature. 1. Introduction “Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by joint swelling, joint tenderness, and destruction of synovial joints, leading to severe disability and premature mortality [1, 2].” The first recognized description of RA was made in 1800 by Dr. Augustin Jacob Landré-Beauvais of Paris [3]. A B Garrod in 1858 named the disease rheumatoid arthritis replacing the old terms arthritis deformans and rheumatic gout [3]. He is thus credited to make a distinction between rheumatoid arthritis, osteoarthritis, and gout [4]. In 1932 the International Committee on Rheumatism was formed which later became American Rheumatism Association and then American College of Rheumatology [4]. TMJ complaints are present in about more than 50% of patients of RA [4, 5]. TMJ is usually among the last joint to be involved and is associated with many clinical signs and symptoms of which pain is a major problem later leading to inflammation, limited movements, swelling (joint stiffness), and muscle spasm [6]. If it occurs in early age it may result in mandibular growth disturbance, facial deformity, and ankylosis and in adult these can vary from mild joint stiffness to total joint disruption with occlusal-facial deformity [7, 8]. The diagnosis of TMJ involvement in RA is exclusionary based on history, physical findings, radiographic study, and lab testing. Hence a multidisciplinary approach is necessary [8, 9]. The present paper reports a case of RA with bilateral TMJ involvement with its classical radiographic findings. 2. Case Report A 29-year-old female patient complained of pain in front of ear bilaterally and discomfort during mouth opening since last 2 months. Associated complains reported anorexia, nervousness, fatigue, and weakness. Four weeks later she began to feel continuous throbbing pain in the joints which aggravated during chewing. Gradually the pain became very intense, making it difficult for the patient to open the mouth, associated with clicking sound while
References
[1]
D. L. Scott, F. Wolfe, and T. W. J. Huizinga, “Rheumatoid arthritis,” The Lancet, vol. 376, no. 9746, pp. 1094–1108, 2010.
[2]
C. Parita, K. Girish, and G. Sreenivas, “Bilateral TMJ involvement in rheumatoid arthritis, a case report,” Journal of Oral Health Research, vol. 2, no. 3, pp. 74–79, 2011.
[3]
D. Kori and S. Stephen, Osteoarthritis and Rheumatoid Arthritis: Pathophysiology, Diagnosis, and Treatment, Nurse Practitioner Healthcare Foundation, 2012.
[4]
B. Bruce and G. Martin, “Temporomandibular disorders,” in Burket’s Textbook of Oral Medicine: Diagnosis and Treatment, pp. 271–306, Elsevier, Canada, 11th edition, 2008.
[5]
C. S. Crowson, E. L. Matteson, E. Myasoedova et al., “The lifetime risk of adult-onset rheumatoid arthritis and other inflammatory autoimmune rheumatic diseases,” Arthritis & Rheumatism, vol. 63, no. 3, pp. 633–639, 2011.
[6]
K. Moen, L. T. Bertelsen, S. Hellem, R. Jonsson, and J. G. Brun, “Salivary gland and temporomandibular joint involvement in rheumatoid arthritis: relation to disease activity,” Oral Diseases, vol. 11, no. 1, pp. 27–34, 2005.
[7]
R. C. Williams Jr., “Autoimmune mechanisms involved in the pathogenesis of rheumatoid arthritis,” Advances in Dental Research, vol. 10, no. 1, pp. 47–51, 1996.
[8]
J. P. Okeson, “Etiology and identification of functional disturbances in masticatory system,” in Management of Temporomandibular Disorders and Occlusion, pp. 147–364, Mosby, New York, NY, USA, 5th edition, 2003.
[9]
R. L. Seymour, V. L. Crouse, and W. B. Irby, “Temporomandibular ankylosis secondary to rheumatoid arthritis: report of a case,” Oral Surgery Oral Medicine and Oral Pathology, vol. 40, no. 5, pp. 584–589, 1975.
[10]
S. Cohen and P. Emery, “The American College of Rheumatology/European League against Rheumatism criteria for the classification of rheumatoid arthritis: a game changer,” Arthritis & Rheumatism, vol. 62, no. 9, pp. 2592–2594, 2010.
[11]
D. Abhijeet and D. Shirish, “Clinical and CT scan evaluation of temporomandibular joints with osteoarthritis and rheumatoid arthritis,” Journal of Indian Academy of Oral Medicine and Radiology, vol. 22, no. 4, pp. 1–5, 2010.
[12]
F. Ardic, D. Gokharman, S. Atsu, S. Guner, M. Yilmaz, and R. Yorgancioglu, “The comprehensive evaluation of temporomandibular disorders seen in rheumatoid arthritis,” Australian Dental Journal, vol. 51, no. 1, pp. 23–28, 2006.
[13]
ü. Voog, P. Alstergren, S. Eliasson, E. Leibur, R. Kallikorm, and S. Kopp, “Inflammatory mediators and radiographic changes in temporomandibular joints of patients with rheumatoid arthritis,” Acta Odontologica Scandinavica, vol. 61, no. 1, pp. 57–64, 2003.
[14]
G. W. Gynther and G. Tronje, “Comparison of arthroscopy and radiography in patients with temporomandibular joint symptoms and generalized arthritis,” Dentomaxillofacial Radiology, vol. 27, no. 2, pp. 107–112, 1998.
[15]
L. M. J. Helenius, D. Hallikainen, I. Helenius et al., “Clinical and radiographic findings of the temporomandibular joint in patients with various rheumatic diseases. A case-control study,” Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology, vol. 99, no. 4, pp. 455–463, 2005.
[16]
A. S. Franks, “Temporomandibular joint in adult rheumatoid arthritis. A comparative evaluation of 100 cases,” Annals of the Rheumatic Diseases, vol. 28, no. 2, pp. 139–145, 1969.
[17]
F. C. Arnett, S. M. Edworthy, D. A. Bloch et al., “The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis,” Arthritis & Rheumatism, vol. 31, no. 3, pp. 315–324, 1988.
[18]
P. Goupille, B. Fouquet, P. Cotty, D. Goga, and J.-P. Valat, “Direct coronal computed tomography of the temporomandibular joint in patients with rheumatoid arthritis,” British Journal of Radiology, vol. 65, no. 779, pp. 955–960, 1992.
[19]
H. Kurita, Y. Kojima, A. Nakatsuka, T. Koike, H. Kobayashi, and K. Kurashina, “Relationship between temporomandibular joint (TMJ)-related pain and morphological changes of the TMJ condyle in patients with temporomandibular disorders,” Dentomaxillofacial Radiology, vol. 33, no. 5, pp. 329–333, 2004.
[20]
E. Uotila, “The temporomandibular joint in adult rheumatoid arthritis,” Acta Odontologica Scandinavica, vol. 22, pp. 49–58, 1964.