Fused teeth may cause aesthetic, spacing, periodontal, eruption, and caries problems. The present case report describes a 7-year-old boy patient with a chief complaint of unerupted maxillary incisor. Radiographic examination indicated a fused tooth which had two fused roots but two independent root canals. A complex management of a fused tooth is really difficult to standardize. In this case an orthodontic, endodontic, and surgical treatment (intentional replantation) allowed the tooth to be retained until 18 years following intervention. Maintenance of the root and alveolar bone in young adults at least until full skeletal maturation should be the main treatment objective. 1. Introduction Dentition development is a very complex process either in the primary or in the permanent tooth. Some authors have proposed a model of genetic network regulation in tooth formation; it seems obvious that most human congenital malformations and dental defects are caused by mutations in developmental regulatory genes. There would be a molecular basis of dental defects [1]. Fusion and gemination are considered abnormalities in tooth development. It is often difficult to differentiate between gemination and fusion and it was common to refer to these anomalies as “double teeth,” “double formations,” “joined teeth,” “fused teeth” or “dental twinning” [2–5]. In gemination the subdivision of the tooth bud is incomplete, giving rise to two dental units, the width of which in the mesiodistal dimension can be twice the dimensions of a single dental unit usually sharing a single root, pulp chamber and root canal. This bifid tooth is considered as a single tooth [6, 7]. By contrast, in fusion the originally separate tooth buds unite at the crown level (enamel) or at the crown and root levels (enamel and dentine), yielding a single large tooth during the odontogenesis, when the crown is not yet mineralized [8, 9]. Both anomalies occur more frequently in the primary dentition, particularly in the canine-incisor region, involving maxillary central and lateral incisors and mandibular lateral incisors and canines [2]. The incidence of unilateral occurrence is estimated in the literature to be 0.5% in the deciduous and 0.1% in the permanent dentition. There seems to be an overall lower incidence of double teeth in Caucasians than in Asians [10]. The aetiology of fusion is still unknown, but the influence of pressure or physical forces producing close contact between two developing teeth was reported as a possible cause. Gemination can be interpreted as an attempt of a supernumerary
References
[1]
I. Thesleff, “Genetic basis of tooth development and dental defects,” Acta Odontologica Scandinavica, vol. 58, no. 5, pp. 191–194, 2000.
[2]
S. Sivolella, E. Bressan, V. Mirabal, E. Stellini, and M. Berengo, “Extraoral endodontic treatment, odontotomy and intentional replantation of a double maxillary lateral permanent incisor: case report and 6-year follow-up,” International Endodontic Journal, vol. 41, no. 6, pp. 538–546, 2008.
[3]
W. K. Duncan and M. L. Helpin, “Bilateral fusion and gemination: a literature analysis and case report,” Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology, vol. 64, no. 1, pp. 82–87, 1987.
[4]
A. H. Brook and G. B. Winter, “Double teeth. A retrospective study of “geminated” and “fused” teeth in children,” British Dental Journal, vol. 129, no. 3, pp. 123–130, 1970.
[5]
S. W. Yuen, J. C. Chan, and S. H. Wei, “Double primary teeth and their relationship with the permanent successors: a radiographic study of 376 cases,” Pediatric Dentistry, vol. 9, no. 1, pp. 42–48, 1987.
[6]
R. E. Rada, “Perio-prosthetic rehabilitation of a geminated central incisor,” Practical Periodontics and Aesthetic Dentistry, vol. 3, no. 7, pp. 23–26, 1991.
[7]
S. Aryanpour, P. Bercy, and J.-P. van Nieuwenhuysen, “Endodontic and periodontal treatments of a geminated mandibular first premolar,” International Endodontic Journal, vol. 35, no. 2, pp. 209–214, 2002.
[8]
B. Ozden, K. Gunduz, S. Ozer, A. Oz, and F. O. Ozden, “The multidisciplinary management of a fused maxillary central incisor with a talon cusp,” Australian Dental Journal, vol. 57, no. 1, pp. 98–102, 2012.
[9]
A. H. B. Schuurs and C. van Loveren, “Double teeth: review of the literature,” Journal of Dentistry for Children, vol. 67, no. 5, pp. 313–325, 2000.
[10]
G. L. Tasa and J. R. Lukacs, “The prevalence and expression of primary double teeth in western India,” Journal of Dentistry for Children, vol. 68, no. 3, pp. 196–200, 2001.
[11]
P. A. Surmont, L. C. Martens, and L. G. de Craene, “A complete fusion in the primary human dentition: a histological approach,” Journal of Dentistry for Children, vol. 55, no. 5, pp. 362–367, 1988.
[12]
T. Cetinbas, S. Halil, M. O. Akcam, S. Sari, and S. Cetiner, “Hemisection of a fused tooth,” Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology, vol. 104, no. 4, pp. e120–e124, 2007.
[13]
A. K. Melnik, “Orthodontic movement of a supplemental maxillary incisor through the midpalatal suture area,” The American Journal of Orthodontics and Dentofacial Orthopedics, vol. 104, no. 1, pp. 85–90, 1993.
[14]
M. Atasu and H. Cimilli, “Fusion of the permanent maxillary right incisor to a supernumerary tooth in association with a gemination of permanent maxillary left central incisor: a dental, genetic and dermatoglyphic study,” Journal of Clinical Pediatric Dentistry, vol. 24, no. 4, pp. 329–333, 2000.
[15]
M. A. O. Al-Omari, F. N. Hattab, A. M. G. Darwazeh, and P. M. H. Dummer, “Clinical problems associated with unusual cases of talon cusp,” International Endodontic Journal, vol. 32, no. 3, pp. 183–190, 1999.
[16]
F. N. Hattab, O. M. Yassin, and K. S. al-Nimri, “Talon cusp—clinical significance and management: case reports,” Quintessence International, vol. 26, no. 2, pp. 115–120, 1995.
[17]
M. Mupparapu, S. R. Singer, and J. H. Goodchild, “Dens evaginatus and dens invaginatus in a maxillary lateral incisor: report of a rare occurrence and review of literature,” Australian Dental Journal, vol. 49, no. 4, pp. 201–203, 2004.
[18]
W. P. Weglarz, M. Tanasiewicz, T. Kupka, T. Skórka, Z. Su?ek, and A. Jasiński, “3D MR imaging of dental cavities—an in vitro study,” Solid State Nuclear Magnetic Resonance, vol. 25, no. 1–3, pp. 84–87, 2004.
[19]
F. Baratto Filho, S. Zaitter, G. A. Haragushiku, E. A. de Campos, A. Abuabara, and G. M. Correr, “Analysis of the internal anatomy of maxillary first molars by using different methods,” Journal of Endodontics, vol. 35, no. 3, pp. 337–342, 2009.
[20]
A. Mancuso, “The treatment of fusion and supernumerary maxillary central incisors: a case report,” General Dentistry, vol. 51, no. 4, pp. 343–345, 2003.
[21]
E. B. Tuna, M. Yildirim, F. Seymen, K. Gencay, and M. Ozgen, “Fused teeth: a review of the treatment options,” Journal of Dentistry for Children, vol. 76, no. 2, pp. 109–116, 2009.
[22]
G. Malcic Prpic-Mehicic, “Conservative treatment of fused teeth in permanent dentition,” Acta Stomatologica Croatica, vol. 39, pp. 327–328, 2005.
[23]
G. Olivan-Rosas, J. López-Jiménez, M. J. Jiménez-Prats, and M. Piqueras-Hernández, “Considerations and differences in the treatment of a fused tooth,” Medicina Oral, vol. 9, pp. 224–228, 2004.
[24]
M. Tsukiboshi, Autotransplantation of Teeth, Quintessence Publishing, Chicago, Ill, USA, 2001.
[25]
T. Tsurumachi and T. Kuno, “Endodontic and orthodontic treatment of a cross-bite fused maxillary lateral incisor,” International Endodontic Journal, vol. 36, no. 2, pp. 135–142, 2003.
[26]
D. Schwartz-Arad, L. Levin, and M. Ashkenazi, “Treatment options of untreatable traumatized anterior maxillary teeth for future use of dental implantation,” Implant Dentistry, vol. 13, no. 2, pp. 120–128, 2004.
[27]
J. O. Andreasen, M. K. Borum, H. L. Jacobsen, and F. M. Andreasen, “Replantation of 400 avulsed permanent incisors. Part 1. Diagnosis of healing complications,” Endodontics and Dental Traumatology, vol. 11, no. 2, pp. 51–58, 1995.
[28]
O. M. Gerhardt, B. M. C. Rockenbach, F. P. Wehmeyer, J. J. da Cunha Filho, and E. Puricelli, “Scanning electron microscopy resection with burs and lasers,” Chirurg, vol. 23, pp. 25–30, 2010.
[29]
A. Samara, Y. Sarri, D. Stravopodis, G. N. Tzanetakis, E. G. Kontakiotis, and E. Anastasiadou, “A comparative study of the effects of three root-end filling materials on proliferation and adherence of human periodontal ligament fibroblasts,” Journal of Endodontics, vol. 37, no. 6, pp. 865–870, 2011.
[30]
Y. S. A. Fernández, B. M. I. Leco, and G. J. M. Martínez, “Metaanalysis of filler materials in periapical surgery,” Medicina Oral, vol. 13, pp. 180–185, 2008.