All Title Author
Keywords Abstract

Publish in OALib Journal
ISSN: 2333-9721
APC: Only $99

ViewsDownloads

Relative Articles

More...

Caseous Necrosis of Mitral Annulus: A Rare Cause of Stroke

DOI: 10.1155/2013/748241

Full-Text   Cite this paper   Add to My Lib

Abstract:

The current report describes a rare case of a caseous necrosis presenting as a pseudotumor in ventricle, revealed by stroke. Cerebral MRI, showing multiples lacunes, evocates a cardioembolic mechanism. Transthoracic and transesophageal echocardiography demonstrate a large hyperechogenic mass fixed to the posterior mitral valve and annulus while thoracic tomography revealed a fully calcified lesion, at the mitral annulus, evocative of caseus necrosis. Medical therapy was preferred (anticoagulation), because of her age and the decaying nature of surgery. 1. Case Report An 83-year-old woman, with prior hypertension and dyslipidemia, presented to the emergency room for sudden dysarthria and facial paralysis. Physical examination was unremarkable, except a mitral regurgitation murmur. Biological tests were normal. Cerebral computed tomography (CT) imaging revealed a lacune in the left corona radiata whereas angio-CT showed only moderate atherosclerosis of the carotid arteries. Cerebral magnetic resonance imaging (MRI) (Figure 1(a)) exposed multiple infra- and supratentorial infarcts suggesting cardioembolic strokes. Figure 1: (a) Cerebral MRI shows multiple infarcts. ((b) and (d)) Cardiac CT shows a large calcified tumor at the insertion of the mitral annulus. (c) Transesophageal echocardiography shows a hyperechogenic, unobtrusive tumor fixed to the posterolateral wall of the left ventricle. ECG was normal and 48-hour continuous cardiac monitoring did not reveal arrhythmia. Transthoracic echocardiography (TTE) showed a preserved left ventricular ejection fraction but an increased left atrial size due to a chronic mitral regurgitation (MR). The mechanism of this grade II MR was a posterior mitral leaflet tethering secondary to a large hyperechogenic immobile growth, measured at 39 × 24?mm, fixed to the posterolateral wall of the left ventricle. There was no mitral stenosis nor aortic valvular disease associated. Cardiac CT (Figures 1(b) and 1(d)) performed in order to analyze this valvular pseudotumor revealed a large calcified tumor, inserted to the mitral annulus evocating caseous necrosis. Transesophageal echocardiography (Figure 1(c)) allowed high-quality images and excluded thrombi and foramen ovale. We reached a rare case of a caseous necrosis presenting as a left ventricular pseudotumor and revealed by transient ischemic attack. Considering embolic complications, surgical excision was discussed to prevent recurrence, but medical therapy with prolonged anticoagulation was preferred because of difficulties of such a surgery and the advanced age of the

References

[1]  Y. Adler, N. Fink, D. Spector, I. Wiser, and A. Sagie, “Mitral annulus calcification—a window to diffuse atherosclerosis of the vascular system,” Atherosclerosis, vol. 155, no. 1, pp. 1–8, 2001.
[2]  E. J. Benjamin, J. F. Plehn, R. B. D'Agostino et al., “Mitral annular calcification and the risk of stroke in an elderly cohort,” New England Journal of Medicine, vol. 327, no. 6, pp. 374–379, 1992.
[3]  H. R. Malaterre, G. Habib, E. Leude, C. Malmejac, A. Vaillant, and P. Djiane, “Embolic thrombus on mitral anulus calcification,” Journal of the American Society of Echocardiography, vol. 9, no. 6, pp. 894–896, 1996.
[4]  J. H. Stein and J. S. Soble, “Thrombus associated with mitral valve calcification: a possible mechanism for embolic stroke,” Stroke, vol. 26, no. 9, pp. 1697–1699, 1995.
[5]  B. Chevalier, P. Reant, S. Laffite, and L. Barandon, “Spontaneous fistulization of a caseous calcification of the mitral annulus: an exceptional cause of stroke,” European Journal of Cardio-Thoracic Surgery, vol. 39, no. 6, pp. e184–e185, 2011.

Full-Text

comments powered by Disqus

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133

WeChat 1538708413