Cardiac Fibroelastoma: A Rare Cause of Stroke in Young Adults

A 26-year-old man presenting with a transient episode of dysarthria and dizziness, 3 weeks prior to admission, was referred to our center to be evaluated for transient ischemic attack (TIA). The patient had been previously admitted to a different hospital and echocardiography was reported normal at that center, but upon presenting to our institution strand-like masses in the left ventricle (LV) were detected. Transesophageal echocardiography (TEE) revealed two distinct mobile LV masses suggesting a diagnosis of papillary fibroelastoma. CT angiography and histopathological studies confirmed this diagnosis. 1. Case Report A 26-year-old man presenting with an episode of dysarthria and dizziness 3 weeks prior to admission was referred to our center to be evaluated for transient ischemic attack (TIA). His past medical history showed no evidence of previous illness. On admission, physical examination showed that he was in sinus rhythm, had a pulse rate of 75？bpm, and a blood pressure of 100/60？mm？Hg. On auscultation, he had no murmur or carotid bruit. Laboratory tests were normal. He had a normal electrocardiogram and chest X-ray. Initial cardiac evaluation was also normal. The patient had been previously admitted to a different hospital which had performed transthoracic echocardiogram and reported it as normal. The patient was referred for transesophageal echocardiography (TEE) to rule out of patent foramen ovale (PFO). We performed another transthoracic echocardiogram (TTE), but mobile strand-like masses in left ventricular (LV) were detected (Figure 1). TEE also revealed two distinct highly mobile filamentous LV masses, suggesting papillary fibroelastoma (Figures 2(a) and 2(b)). One mass measuring 5 × 0.6？cm originated from the posterior wall, near the apex, and another mass measuring 3 × 0.6？cm originated from the mitral valve (MV) annulus just beside the posterior MV leaflet. Both of the masses extended toward LV outflow tract. Both aortic and mitral valve were spare, but chordae tendina was suspected to be involved. CT angiography confirmed the diagnosis. The patient was given anticoagulant therapy and referred for surgery. At operation, two large beading tumors were found in the LV (Figure 3). One of the tumors was attached to posterior leaflet of the MV and the other one was attached to the posterior papillary muscle adjacent to the chordae tendina. The tumors were successfully excised via mitral valve approach. Chordae reconstruction and MV annuloplasty were performed for the patient. The postoperative recovery was uneventful. Follow-up TEE revealed