Background. Respiratory complaints are commonly encountered in medicine and respiratory diseases place a high burden on healthcare infrastructure. Healthcare planning should be based on adequate information: this study will help us to analyze the pattern of respiratory disease admissions in the medical wards in a developing country. Methods. The medical records of patients admitted into the medical wards over a 5-year period were retrieved and reviewed. Information obtained included demography, diagnosis, comorbid conditions, and risk factors for respiratory disease. Results. Three thousand four hundred and ninety patients were admitted into the medical wards with 325 (9.3%) of them diagnosed with a respiratory condition. There were 121 females and 204 males. The average age of the patients was 40.7 ± 14.7 years. Only 7% of the patients smoked cigarette. The commonest respiratory conditions were tuberculosis (66.8%) and pneumonia (24.9%). The commonest comorbidity was HIV infection (39.7%). Tuberculosis/HIV coinfection rate was 50.7%. HIV infection was the single most important predictor of an adverse outcome (OR 5.1, 95% CI 2.05–12.7, ). Conclusion. Infective conditions make up a large percentage of respiratory diseases in low income countries with HIV infection constituting a significant risk factor for a poor disease outcome. 1. Introduction Respiratory complaints such as cough and catarrh are some of the commonest symptoms encountered in medicine. This is due in part to the large surface area; nearly 70?m2 of the lungs present to the atmosphere [1]. The atmosphere that we breathe is more than just “air.” In reality, it is a complex mixture of ambient gases and environmental particulates to which pathogen containing droplets are added when respiratory secretions are coughed or sneezed out by others. Respiratory diseases constitute a major cause of morbidity and mortality worldwide. The top four respiratory diseases, lower respiratory tract infections, chronic obstructive pulmonary disease (COPD), tuberculosis, and lung cancer, are among the ten leading causes of death worldwide [2]. In Africa, lower respiratory tract infection and tuberculosis are ranked 2nd and 8th, respectively [3]. In developed countries, respiratory diseases feature prominently in the top ten causes of morbidity and mortality [4–7]. In Nigeria, lower respiratory tract infections constituted the second leading cause of death in all age brackets in 2002, a year in which TB was the seventh leading cause of death, accounting for 4% of all deaths [8]. In India another developing
References
[1]
M. Ochs and E. R. Weibel, “Functional design of the human lungs for gas exchange,” in Fishman’s Pulmonary diseases and disorders, vol. 10036, pp. 23–25, McGraw Hill, New York, NY, USA, 4th edition, 2008.
[2]
R. Lozano, M. Naghavi, K. Foreman, et al., “Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010,” The Lancet, vol. 380, pp. 2095–2128, 2012.
[3]
WHO, “Global Burden of Disease: 2004 update,” vol. 1211, World Health Organisation, Geneva, Switzerland, 2008http://www.who.int/healthinfo/global_burden_disease/2004_report_update/en/index.html.
[4]
BTS, “The burden of lung disease: a statistical report from the British Thoracic Society,” 2nd ed., British Thoracic Society, London, UK, 2006, http://www.brit-thoracic.org.uk/delivery-of-respiratory-care/burden-of-lung-disease-reports.aspx.
[5]
R. Hubbard, “The burden of lung disease,” Thorax, vol. 61, no. 7, pp. 557–558, 2006.
[6]
R. Loddenkemper, G. J. Gibson, and Y. Sibille, “Respiratory health and disease in Europe: the new European Lung White Book,” European Respiratory Journal, vol. 42, pp. 559–563, 2013.
[7]
D. E. Schraufnagel, F. Blasi, M. Kraft, M. Gaga, P. Finn, and K. F. Rabe, “An official American Thoracic Society and European Respiratory Society policy statement: disparities in respiratory health,” European Respiratory Journal, vol. 42, pp. 906–915, 2013.
[8]
WHO, “Country Health System Fact Sheet 2006: Nigeria,” WHO, Geneva, Switzerland, 2006, http://www.afro.who.int/home/countries/fact_sheets/nigeria.pdf.
[9]
A. Ramanakumar and C. Aparajita, “Respiratory disease burden in rural India: a review from multiple data sources,” The Internet Journal of Epidemiology, vol. 2, no. 2, 2005.
[10]
O. O. Desalu, J. A. Oluwafemi, and O. Ojo, “Respiratory diseases morbidity and mortality among adults attending a tertiary hospital in Nigeria,” Jornal Brasileiro de Pneumologia, vol. 35, no. 8, pp. 745–752, 2009.
[11]
O. S. Alamoudi, “Prevalence of respiratory diseases in hospitalized patients in Saudi Arabia: a 5 years study 1996–2000,” Annals of Thoracic Medicine, vol. 1, no. 2, pp. 76–80, 2006.
[12]
B. R. Pokharel, S. Humagain Pant P, R. Gurung, R. Koju, and T. R. Bedi, “Spectrum of diseases in a medical ward of a teaching hospital in a developing country,” Journal of College of Medical Sciences-Nepal, vol. 8, no. 2, pp. 7–11, 2012.
[13]
A. El-Menyar, M. Zubaid, A. Shehab et al., “Prevalence and impact of cardiovascular risk factors among patients presenting with acute coronary syndrome in the middle east,” Clinical Cardiology, vol. 34, no. 1, pp. 51–58, 2011.
[14]
C. T. Sreeramareddy, N. Ramakrishnareddy, H. N. Harsha Kumar, B. Sathian, and J. T. Arokiasamy, “Prevalence, distribution and correlates of tobacco smoking and chewing in Nepal: a secondary data analysis of Nepal Demographic and Health Survey-2006,” Substance Abuse, vol. 6, no. 1, article 33, 2011.
[15]
E. G. Adepoju, S. A. Olowookere, N. A. Adeleke, O. T. Afolabi, F. O. Olajide, and O. O. Aluko, “A population based study on the prevalence of cigarette smoking and smokers’ characteristics at Osogbo, Nigeria,” Tobacco Use Insights, vol. 6, pp. 1–5, 2013.
[16]
National Population Commission (NPC) [Nigeria] and ICF Macro, “Nigeria Demographic and Health Survey 2008,” National Populaton Commission and ICF Macro, Abuja, Nigeria, 2009, http://www.measuredhs.com/pubs/pdf/FR222/FR222.pdf.
[17]
G. Pennap, S. Makpa, and S. Ogbu, “The prevalence of HIV/AIDS among tuberculosis patients in a tuberculosis/leprosy Referral Center in Alushi, Nasarawa State, Nigeria,” The Internet Journal of Epidemiology, vol. 8, no. 1, 2010.
[18]
E. O. Sanya, T. M. Akande, G. Opadijo, J. K. Olarinoye, and B. J. Bojuwoye, “Pattern and outcome of medical admission of elderly patients seen at University of Ilorin Teaching Hospital, Ilorin,” African Journal of Medicine and Medical Sciences, vol. 37, no. 4, pp. 375–381, 2008.
[19]
P. Paliogiannis, F. Attene, A. Cossu, et al., “Lung cancer epidemiology in North Sardinia, Italy,” Multidisciplinary Respiratory Medicine, vol. 8, no. 1, article 45, 2013.
[20]
V. N. Davis, A. Lavender, R. Bayakly, K. Ray, and T. Moon, “Using current smoking prevalence to project lung cancer morbidity and mortality in Georgia by 2020,” Preventing Chronic Disease, vol. 10, Article ID 120271, 2013.
[21]
B. Tessema, A. Muche, A. Bekele, D. Reissig, F. Emmrich, and U. Sack, “Treatment outcome of tuberculosis patients at Gondar University Teaching Hospital, Northwest Ethiopia. A five - Year retrospective study,” BMC Public Health, vol. 9, article 371, 2009.
[22]
O. A. Busari, O. T. Olarewaju, and O. E. Busari, “Management and outcomes of suspected pulmonary tuberculosis in a resource-poor setting,” Internet Journal of Pulmonary Medicine, vol. 11, no. 2, 2010.
[23]
A. A. Salako and O. O. Sholeye, “Management outcomes of tuberculosis cases in a tertiary hospital in Southwestern Nigeria,” Journal of Community Medicine and Health Education, vol. 2, no. 2, article 122, 2012.
[24]
D. Ogoina, R. O. Obiako, H. M. Muktar, M. Adeiza, A. Babadoko, and A. Hassan, “Morbidity and mortality patterns of hospitalised adult HIV/AIDS patients in the era of highly active antiretroviral therapy: a 4-year retrospective review from Zaria, Northern Nigeria,” AIDS Research and Treatment, vol. 2012, Article ID 940580, 10 pages, 2012.
[25]
A. N. Gyuse, I. E. Bassey, N. E. Udonwa, I. B. Okokon, and E. E. Philip-Ephraim, “HIV/AIDS related mortality among adult medical patients in a tertiary health institution in South-South, Nigeria,” Asian Pacific Journal of Tropical Medicine, vol. 3, no. 2, pp. 141–144, 2010.
[26]
C. Akolo, C. O. Ukoli, G. N. Ladep, and J. A. Idoko, “The clinical features of HIV/AIDS at presentation at the Jos University Teaching Hospital,” Nigerian Journal of Medicine, vol. 17, no. 1, pp. 83–87, 2008.