Introduction. Single-incision laparoscopic colectomy (SILC) is a viable and safe technique; however, there are no single-institution studies comparing outcomes of SILC for colon cancer with well-established minimally invasive techniques. We evaluated the short-term outcomes following SILC for cancer compared to a group of well-established minimally invasive techniques. Methods. Fifty consecutive patients who underwent SILC for colon cancer were compared to a control group composed of 50 cases of minimally invasive colectomies performed with either conventional multiport or hand-assisted laparoscopic technique. The groups were paired based on the type of procedure. Demographics, intraoperative, and postoperative outcomes were assessed. Results. With the exception of BMI, demographics were similar between both groups. Most of the procedures were right colectomies ( ) and anterior resections ( ). There were no significant differences in operative time (127.9 versus 126.7?min), conversions (0 versus 1), complications (14% versus 8%), length of stay (4.5 versus 4.0 days), readmissions (2% versus 2%), and reoperations (2% versus 2%). Oncological outcomes were also similar between groups. Conclusions. SILC is an oncologically sound alternative for the management of colon cancer and results in similar short-term outcomes as compared with well-established minimally invasive techniques. 1. Introduction Minimally invasive colorectal surgery has been demonstrated to be a safe and efficacious approach for the surgical management of benign and malignant conditions [1–3]. Conventional multiport laparoscopy was the first utilized minimally invasive surgical modality for the management of colorectal diseases [4]. Thereafter, hand-assisted laparoscopic surgery was in part developed to overcome some of the technical challenges of conventional laparoscopic surgery [5]. These approaches require several incisions for port placement and specimen extraction, which may potentially results in complications such as extraperitoneal insufflation, bleeding, and internal organ injury [6]. In an attempt to progress with less invasive techniques and diminish potential complications, minimally invasive colorectal surgery is trending towards reduced-port modalities. Single-incision laparoscopic colectomy (SILC) is an emerging surgical technique that has gained enthusiasm and interest in the field of colorectal surgery [7–9]. In this approach, the entirety of the procedure is performed through one incision, which would be otherwise required for specimen extraction, and it is potentially
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