Introduction and Aim. Substance abuse imposes hazards on human health in all biopsychosocial aspects. Limited studies exist on epidemiology of substance abuse and its trend in rural areas. The present study aimed to compare substance abuse in one of the rural areas of southeast Iran, in a 12-year period (2000 and 2012). Design and Methods. In a household survey conducted in 2012, in Dashtkhak/Kerman, 1200 individuals above 12 years of age completed a questionnaire to determine their frequency of substance abuse. The questionnaire included the following three areas: demographic characteristics, frequency of substance abuse and ease of access to various drugs. Results. Among 900 completed questionnaires, majority of the participants (61.8%) were below 30 years of age and among them 54.4% were male. Cigarette (17.0%), opium (15.7%) and opium residue (9.0%) were the most frequent substances abused on a daily basis. Based on the participant’s opinion, we conclude that the ease of access to cigarette, waterpipe and opium contributed to their increase in consumption compared with earlier years. Discussion and Conclusion. The steady rise in substance abuse in rural communities demands immediate attention and emergency preventive measures from policy makers. 1. Introduction Substance abuse poses a major political, social and health challenge worldwide [1]. Besides being a personal risk, addiction is a social problem and imposes harmful and permanent effects on society. At present, 3.6%–6.9% of adults (15–64-years-old individuals) are under the influence of illicit substances [2]. According to the World Drug Report 2013, since 2008, the number of illicit drug users has shown 18% increase; rise in population and ease of availability appears to be the two common reasons [2]. Substance abuse in Iran, one of the Middle East countries, has a historical origin. During World War I, among 250,000 individuals of the Tehran municipality, 25,000 were reported to be addicted to opium [3]. In recent centuries, opium has been prescribed for pain relief in Iran by traditional physicians. These traditions are stronger among rural populations owing to a lack of access to trained physicians. The usage of opium had been so common in rural areas that mothers often exposed babies to opium in an effort to calm them and sleep better [3]. The past two centuries have seen several changes with respect to handling illicit substances in Iran, from open access to death penalty for carrying illicit drugs. At present, Iran policy against illicit drugs is considered to be a combination of war
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