Individuals with autism spectrum disorders (ASD) have impairments in social interaction, communicative capacity, and behavioral flexibility (core triad). Three major cognitive theories (theory of mind deficit, weak central coherence, and executive dysfunction) seem to explain many of these impairments. Currently, however, the empathizing-systemizing (a newer version of the theory of mind deficit account) and mnesic imbalance theories are the only ones that attempt to explain all these core triadic symptoms of ASD On the other hand, theory of mind deficit in empathizing-systemizing theory is the most influential account for ASD, but its counterpart in the mnesic imbalance theory, faulty procedural memory, seems to occur earlier in development; consequently, this might be a better solution to the problem of the etiology of ASD, if it truly meets the precedence criterion. Hence, in the present paper I review the reasoning in favor of the theory of mind deficit but with a new interpretation based on the mnesic imbalance theory, which posits that faulty procedural memory causes deficits in several cognitive skills, resulting in poor performance in theory of mind tasks. 1. Introduction Autistic disorder is characterized by impairments in reciprocal social interaction, communicative capacity, and repetitive patterns of behavior (core triad) [1]. The term autism spectrum disorders (ASD), which has been used by some mental health professionals as a synonym of pervasive developmental disorder (PDD) [2], implies that these impairments are shared among autistic disorder, Asperger’s syndrome, and pervasive developmental disorder not otherwise specified (PDD-NOS) [3]. However, considering that the diagnosis of PDD-NOS does not require the presence of the three diagnostic domains of the autistic triad (social interaction, communicative capacity and behavioral flexibility), the inclusion of PDD-NOS as an ASD has been questioned [4]. This observation is important because it is hard, if not impossible, to make a cognitive theory on disorders that do not share clinical and etiological features [5]. Consequently, I use the term ASD throughout this work to refer to the group comprised only by autistic disorder and Asperger’s syndrome, whereas both disorders are mentioned separately when they are not forming a group in some mentioned study in this text. On the other hand, when Kanner provided the first clinical description of autistic disorder, he also wrote “Their excellent rote memory… It is difficult to know for certain whether the stuffing as such has contributed
References
[1]
American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders, American Psychiatric Publishing, Washington, DC, USA, 4th edition, 2000.
[2]
M. Tateno, S. Kikuchi, K. Uehara et al., “Pervasive developmental disorders and autism spectrum disorders: are these disorders one and the same?” Psychiatry Investigation, vol. 8, no. 1, pp. 67–70, 2011.
[3]
L. Gabis, H. Wei, A. Azizian et al., “1H-magnetic resonance spectroscopy markers of cognitive and language ability in clinical subtypes of autism spectrum disorders,” Journal of Child Neurology, vol. 23, no. 7, pp. 766–774, 2008.
[4]
M. T. Mercadante, R. J. van der Gaag, and J. S. Schwartzman, “Non-autistic pervasive developmental disorders: rett's syndrome, childhood disintegrative disorder and pervasive developmental disorder not otherwise specified,” Revista Brasileira de Psiquiatria, vol. 28, supplement 1, pp. S12–S20, 2006.
[5]
L. Waterhouse, “Autism overflows: increasing prevalence and proliferating theories,” Neuropsychology Review, vol. 18, no. 4, pp. 273–286, 2008.
[6]
L. Kanner, “Autistic disturbances of affective contact,” The Nervous Child, vol. 2, pp. 217–250, 1943.
[7]
H. Asperger, “Die “autistischen psychopathen” im kindesalter,” Archiv für Psychiatrie und Nervenkrankheiten, vol. 117, no. 1, pp. 76–136, 1944.
[8]
S. Baron-Cohen, A. M. Leslie, and U. Frith, “Does the autistic child have a ‘theory of mind’?” Cognition, vol. 21, no. 1, pp. 37–46, 1985.
[9]
U. Frith, Autism: Explaining the Enigma, Blackwell, Malden, Mass, USA, 1989.
[10]
S. Ozonoff, B. F. Pennington, and S. J. Rogers, “Executive function deficits in high-functioning autistic individuals: relationship to theory of mind,” Journal of Child Psychology and Psychiatry and Allied Disciplines, vol. 32, no. 7, pp. 1081–1105, 1991.
[11]
S. Baron-Cohen, “The extreme male brain theory of autism,” Trends in Cognitive Sciences, vol. 6, no. 6, pp. 248–254, 2002.
[12]
M. á. Romero-Munguía, “Mnesic imbalance: a cognitive theory about autism spectrum disorders,” Annals of General Psychiatry, vol. 7, no. 1, article 20, 2008.
[13]
E. Pisula, “The autistic mind in the light of neuropsychological studies,” Acta Neurobiologiae Experimentalis, vol. 70, no. 2, pp. 119–130, 2010.
[14]
G. Rajendran and P. Mitchell, “Cognitive theories of autism,” Developmental Review, vol. 27, no. 2, pp. 224–260, 2007.
[15]
S. Baron-Cohen, “Autism: the empathizing-systemizing (E-S) theory,” Annals of the New York Academy of Sciences, vol. 1156, pp. 68–80, 2009.
[16]
M. A. Romero-Munguía, “Mnesic imbalance and the neuroanatomy of autism spectrum disorders,” in Autism—A Neurodevelopmental Journey from Genes to Behaviour, V. Eapen, Ed., pp. 425–444, InTech, Rijeka, Croatia, 2011.
[17]
L. Mottron, “Matching strategies in cognitive research with individuals with high-functioning autism: current practices, instrument biases, and recommendations,” Journal of Autism and Developmental Disorders, vol. 34, no. 1, pp. 19–27, 2004.
[18]
I. M. Eigsti, L. Bennetto, and M. B. Dadlani, “Beyond pragmatics: morphosyntactic development in autism,” Journal of Autism and Developmental Disorders, vol. 37, no. 6, pp. 1007–1023, 2007.
[19]
M. Walenski, H. Tager-Flusberg, and M. T. Ullman, “Language in autism,” in Understanding Autism: From Basic Neuroscience to Treatment, S. O. Moldin and J. L. R. Rubenstein, Eds., pp. 175–203, Taylor & Francis, Boca Raton, Fla, USA, 2006.
[20]
S. Ellis Weismer, M. A. Gernsbacher, S. Stronach et al., “Lexical and grammatical skills in toddlers on the autism spectrum compared to late talking toddlers,” Journal of Autism and Developmental Disorders, vol. 41, no. 8, pp. 1065–1075, 2011.
[21]
S. Koolen, C. T. W. M. Vissers, A. W. C. J. Hendriks, J. I. M. Egger, and L. Verhoeven, “The interplay between attentional strategies and language processing in high-functioning adults with autism spectrum disorder,” Journal of Autism and Developmental Disorders, vol. 42, no. 5, pp. 805–814, 2012.
[22]
N. Fisher, F. Happé, and J. Dunn, “The relationship between vocabulary, grammar, and false belief task performance in children with autistic spectrum disorders and children with moderate learning difficulties,” Journal of Child Psychology and Psychiatry and Allied Disciplines, vol. 46, no. 4, pp. 409–419, 2005.
[23]
J. ?sberg, “Patterns of language and discourse comprehension skills in school-aged children with autism spectrum disorders,” Scandinavian Journal of Psychology, vol. 51, no. 6, pp. 534–539, 2010.
[24]
S. Peppe, J. Cleland, F. Gibbon, A. O'Hare, and P. M. Castilla, “Expressive prosody in children with autism spectrum conditions,” Journal of Neurolinguistics, vol. 24, no. 1, pp. 41–53, 2011.
[25]
M. A. Romero-Munguía, “Memoria procesal deficiente y alteraciones de la comunicación en la patogenia del autismo infantil,” Neurología, Neurocirugía y Psiquiatría, vol. 35, no. 4, pp. 203–208, 2002.
[26]
H. Tager-Flusberg, “Language and understanding minds: connections in autism,” in Understanding Other Minds: Perspectives From Autism and Developmental Cognitive Neuroscience, S. Baron-Cohen, H. Tager-Flusberg, and D. J. Cohen, Eds., pp. 124–149, Oxford University Press, Oxford, UK, 2nd edition, 2000.
[27]
M. T. Ullman, “The declarative/procedural model of lexicon and grammar,” Journal of Psycholinguistic Research, vol. 30, no. 1, pp. 37–69, 2001.
[28]
F. Happé, Autism: An Introduction to Psychological Theory, Taylor & Francis, London, UK, 1994.
[29]
M. A. Romero-Munguía, “Mnesic imbalance or hyperthymestic syndrome as cause of autism symptoms in Shereshevskii,” in Recent Advances in Autism Spectrum Disorders—Volume I, M. Fitzgerald, Ed., pp. 165–187, InTech, Rijeka, Croatia, 2013.
[30]
J. Perner, S. R. Leekam, and H. Wimmer, “Three-year-olds' difficulty with false belief: the case for a conceptual deficit,” British Journal of Developmental Psychology, vol. 5, no. 2, pp. 125–137, 1987.
[31]
J. Perner, U. Frith, A. M. Leslie, and S. R. Leekam, “Exploration of the autistic child's theory of mind: knowledge, belief, and communication,” Child Development, vol. 60, no. 3, pp. 688–700, 1989.
[32]
C. M. Grant, K. J. Riggs, and J. Boucher, “Counterfactual and mental state reasoning in children with autism,” Journal of Autism and Developmental Disorders, vol. 34, no. 2, pp. 177–188, 2004.
[33]
S. Kerr and K. Durkin, “Understanding of thought bubbles as mental representations in children with autism: implications for theory of mind,” Journal of Autism and Developmental Disorders, vol. 34, no. 6, pp. 637–648, 2004.
[34]
H. M. Wellman, S. Baron-Cohen, R. Caswell et al., “Thought-bubbles help children with autism acquire an alternative to a theory of mind,” Autism, vol. 6, no. 4, pp. 343–363, 2002.
[35]
S. E. Lind and D. M. Bowler, “Language and theory of mind in autism spectrum disorder: the relationship between complement syntax and false belief task performance,” Journal of Autism and Developmental Disorders, vol. 39, no. 6, pp. 929–937, 2009.
[36]
C. Lewis and A. Osborne, “Three-year-olds' problems with false belief: conceptual deficit or linguistic artifact?” Child Development, vol. 61, no. 5, pp. 1514–1519, 1990.
[37]
S. B. Day and D. Gentner, “Nonintentional analogical inference in text comprehension,” Memory and Cognition, vol. 35, no. 1, pp. 39–49, 2007.
[38]
E. de Gortari, Introducción a la lógica dialéctica, Fondo de Cultura Económica, México, Mexico, 1956.
[39]
L. Girelli, C. Semenza, and M. Delazer, “Inductive reasoning and implicit memory: evidence from intact and impaired memory systems,” Neuropsychologia, vol. 42, no. 7, pp. 926–938, 2004.
[40]
W. L. Gross and A. J. Greene, “Analogical inference: the role of awareness in abstract learning,” Memory, vol. 15, no. 8, pp. 838–844, 2007.
[41]
S. Ozonoff, S. J. Rogers, and B. F. Pennington, “Asperger's syndrome: evidence of an empirical distinction from high-functioning autism,” Journal of Child Psychology and Psychiatry and Allied Disciplines, vol. 32, no. 7, pp. 1107–1122, 1991.
[42]
S. Baron-Cohen, “The autistic child's theory of mind: a case of specific developmental delay,” Journal of Child Psychology and Psychiatry and Allied Disciplines, vol. 30, no. 2, pp. 285–297, 1989.
[43]
R. de Oliveira-Souza, J. Moll, F. T. Moll, and D. L. Gusm?o De Oliveira, “Executive amnesia in a patient with pre-frontal damage due to a gunshot wound,” Neurocase, vol. 7, no. 5, pp. 383–389, 2001.
[44]
W. E. Winter, M. Broman, A. L. Rose, and A. S. Reber, “The assessment of cognitive procedural learning in amnesia: why the tower of Hanoi has fallen down,” Brain and Cognition, vol. 45, no. 1, pp. 79–96, 2001.
[45]
F. G. E. Happé, “An advanced test of theory of mind: understanding of story characters' thoughts and feelings by able autistic, mentally handicapped, and normal children and adults,” Journal of Autism and Developmental Disorders, vol. 24, no. 2, pp. 129–154, 1994.
[46]
L. Cattaneo, M. Fabbri-Destro, S. Boria et al., “Impairment of actions chains in autism and its possible role in intention understanding,” Proceedings of the National Academy of Sciences of the United States of America, vol. 104, no. 45, pp. 17825–17830, 2007.
[47]
L. Fogassi, P. F. Ferrari, B. Gesierich, S. Rozzi, F. Chersi, and G. Rizzolotti, “Neuroscience: parietal lobe: from action organization to intention understanding,” Science, vol. 308, no. 5722, pp. 662–667, 2005.
[48]
G. Rizzolatti and M. Fabbri-Destro, “Mirror neurons: from discovery to autism,” Experimental Brain Research, vol. 200, no. 3-4, pp. 223–237, 2010.
[49]
A. E. O'Hare, L. Bremner, M. Nash, F. Happé, and L. M. Pettigrew, “A clinical assessment tool for advanced theory of mind performance in 5 to 12 year olds,” Journal of Autism and Developmental Disorders, vol. 39, no. 6, pp. 916–928, 2009.
[50]
T. Jolliffe and S. Baron-Cohen, “The strange stories test: a replication with high-functioning adults with autism or Asperger syndrome,” Journal of Autism and Developmental Disorders, vol. 29, no. 5, pp. 395–406, 1999.
[51]
K. Anastasia, S. R. Leekam, and J. M. Findlay, “Implicit learning of local context in autism spectrum disorder,” Journal of Autism and Developmental Disorders, vol. 42, no. 2, pp. 244–256, 2012.
[52]
S. Baron-Cohen, M. O'Riordan, V. Stone, R. Jones, and K. Plaisted, “Recognition of faux pas by normally developing children and children with asperger syndrome or high-functioning autism,” Journal of Autism and Developmental Disorders, vol. 29, no. 5, pp. 407–418, 1999.
[53]
S. Choudhury, S. J. Blakemore, and T. Charman, “Social cognitive development during adolescence,” Social Cognitive and Affective Neuroscience, vol. 1, no. 3, pp. 165–174, 2006.
[54]
E. H. H. Keulers, E. A. T. Evers, P. Stiers, and J. Jolles, “Age, sex, and pubertal phase influence mentalizing about emotions and actions in adolescents,” Developmental Neuropsychology, vol. 35, no. 5, pp. 555–569, 2010.
[55]
S. H. Mostofsky, M. C. Goldberg, R. J. Landa, and M. B. Denckla, “Evidence for a deficit in procedural learning in children and adolescents with autism: implications for cerebellar contribution,” Journal of the International Neuropsychological Society, vol. 6, no. 7, pp. 752–759, 2000.
[56]
S. Baron-Cohen, T. Jolliffe, C. Mortimore, and M. Robertson, “Another advanced test of theory of mind: evidence from very high functioning adults with autism or Asperger syndrome,” Journal of Child Psychology and Psychiatry and Allied Disciplines, vol. 38, no. 7, pp. 813–822, 1997.
[57]
F. Gregory Ashby and M. J. Crossley, “Interactions between declarative and procedural-learning categorization systems,” Neurobiology of Learning and Memory, vol. 94, no. 1, pp. 1–12, 2010.
[58]
S. Baron-Cohen, S. Wheelwright, J. Hill, Y. Raste, and I. Plumb, “The “reading the mind in the eyes” test revised version: a study with normal adults, and adults with Asperger syndrome or high-functioning autism,” Journal of Child Psychology and Psychiatry and Allied Disciplines, vol. 42, no. 2, pp. 241–251, 2001.
[59]
A. Klin, W. Jones, R. Schultz, F. Volkmar, and D. Cohen, “Visual fixation patterns during viewing of naturalistic social situations as predictors of social competence in individuals with autism,” Archives of General Psychiatry, vol. 59, no. 9, pp. 809–816, 2002.
[60]
T. F. Gross, “The perception of four basic emotions in human and nonhuman faces by children with autism and other developmental disabilities,” Journal of Abnormal Child Psychology, vol. 32, no. 5, pp. 469–480, 2004.
[61]
O. Golan, S. Baron-Cohen, and J. Hill, “The Cambridge Mindreading (CAM) face-voice battery: testing complex emotion recognition in adults with and without Asperger Syndrome,” Journal of Autism and Developmental Disorders, vol. 36, no. 2, pp. 169–183, 2006.
[62]
S. Blakemore, “The social brain in adolescence,” Nature Reviews Neuroscience, vol. 9, no. 4, pp. 267–277, 2008.
[63]
G. B. C. Hall, H. Szechtman, and C. Nahmias, “Enhanced salience and emotion recognition in autism: a PET study,” American Journal of Psychiatry, vol. 160, no. 8, pp. 1439–1441, 2003.
[64]
N. C. Vetter, M. Altgassen, L. Phillips, C. E. Mahy, and M. Kliegel, “Development of affective theory of mind across adolescence: disentangling the role of executive functions,” Developmental Neuropsychology, vol. 38, no. 2, pp. 114–125, 2013.
[65]
R. J. Roberts, L. D. Hager, and C. Heron, “Prefrontal cognitive processes: working memory and inhibition in the antisaccade task,” Journal of Experimental Psychology, vol. 123, no. 4, pp. 374–393, 1994.
[66]
L. Heavey, W. Phillips, S. Baron-Cohen, and M. Rutter, “The awkward moments test: a naturalistic measure of social understanding in autism,” Journal of Autism and Developmental Disorders, vol. 30, no. 3, pp. 225–236, 2000.
[67]
I. Dziobek, S. Fleck, E. Kalbe et al., “Introducing MASC: a movie for the assessment of social cognition,” Journal of Autism and Developmental Disorders, vol. 36, no. 5, pp. 623–636, 2006.
[68]
O. Golan, S. Baron-Cohen, J. J. Hill, and Y. Golan, “The “reading the mind in films” task: complex emotion recognition in adults with and without autism spectrum conditions,” Social neuroscience, vol. 1, no. 2, pp. 111–123, 2006.
[69]
O. Golan, S. Baron-Cohen, and Y. Golan, “The “reading the mind in films” task [child version]: complex emotion and mental state recognition in children with and without autism spectrum conditions,” Journal of Autism and Developmental Disorders, vol. 38, no. 8, pp. 1534–1541, 2008.
[70]
J. L. Barnes, M. V. Lombardo, S. Wheelwright, and S. Baron-Cohen, “Moral dilemmas film task: a study of spontaneous narratives by individuals with autism spectrum conditions,” Autism Research, vol. 2, no. 3, pp. 148–156, 2009.
[71]
S. G. Shamay-Tsoory, H. Harari, J. Aharon-Peretz, and Y. Levkovitz, “The role of the orbitofrontal cortex in affective theory of mind deficits in criminal offenders with psychopathic tendencies,” Cortex, vol. 46, no. 5, pp. 668–677, 2010.
[72]
M. A. Romero-Munguía, “Es la memoria procesal deficiente la causa del comportamiento estereotipado en el autismo,” Psiquiatría, órgano Oficial de Difusión de la Asociación Psiquiátrica Mexicana, A.C., vol. 14, no. 2, pp. 62–65, 1998.