[1] | Specht E, Miyake-Stoner S, Mayfield S (2010) Micro-algae come of age as a platform for recombinant protein production. Biotechnol Lett 32: 1373–1383 Available: http://www.pubmedcentral.nih.gov/article?render.fcgi?artid=2941057&tool=pmcentrez?&rendertype=abstract. Accessed 9 August 2013.
|
[2] | Jones CS, Mayfield SP (2012) Algae biofuels: versatility for the future of bioenergy. Curr Opin Biotechnol 23: 346–351 Available: http://www.ncbi.nlm.nih.gov/pubmed/22104?720. Accessed 14 August 2013.
|
[3] | Pulz O, Gross W (2004) Valuable products from biotechnology of microalgae. Appl Microbiol Biotechnol 65: 635–648 Available: http://www.ncbi.nlm.nih.gov/pubmed/15300?417. Accessed 17 August 2013.
|
[4] | Spolaore P, Joannis-Cassan C, Duran E, Isambert A (2006) Commercial applications of microalgae. J Biosci Bioeng 101: 87–96 Available: http://www.ncbi.nlm.nih.gov/pubmed/16569?602. Accessed 8 August 2013.
|
[5] | Raja R, Hemaiswarya S, Kumar NA, Sridhar S, Rengasamy R (2008) A perspective on the biotechnological potential of microalgae. Crit Rev Microbiol 34: 77–88 Available: http://www.ncbi.nlm.nih.gov/pubmed/18568?862. Accessed 6 August 2013.
|
[6] | TL, Purton S, Becker DK, Collet C (2005) Microalgae as bioreactors. Plant Cell Rep 24: 629–641 Available: http://www.ncbi.nlm.nih.gov/pubmed/16136?314. Accessed 9 August 2013.
|
[7] | Olaizola M (2003) Commercial development of microalgal biotechnology: from the test tube to the marketplace. 20: 459–466 Available: http://www.ncbi.nlm.nih.gov/pubmed/12919?832. Accessed 12 August 2013.
|
[8] | Christaki E, Florou-Paneri P, Bonos E (2011) Microalgae: a novel ingredient in nutrition. Int J Food Sci Nutr 62: 794–799 Available: http://www.ncbi.nlm.nih.gov/pubmed/21574?818. Accessed 27 August 2013.
|
[9] | Chisti Y (2008) Biodiesel from microalgae beats bioethanol. Trends Biotechnol 26: 126–131 Available: http://www.ncbi.nlm.nih.gov/pubmed/18221?809. Accessed 7 August 2013.
|
[10] | Barnes D, Franklin S, Schultz J, Henry R, Brown E, et al. (2005) Contribution of 5′- and 3′-untranslated regions of plastid mRNAs to the expression of Chlamydomonas reinhardtii chloroplast genes. Mol Genet Genomics 274: 625–636 Available: http://www.ncbi.nlm.nih.gov/pubmed/16231?149. Accessed 5 August 2013.
|
[11] | Mayfield SP, Manuell AL, Chen S, Wu J, Tran M, et al. (2007) Chlamydomonas reinhardtii chloroplasts as protein factories. Curr Opin Biotechnol 18: 126–133 Available: http://www.ncbi.nlm.nih.gov/pubmed/17317?144. Accessed 8 August 2013.
|
[12] | JN, Oyler GA, Wilkinson L, Betenbaugh MJ (2008) A green light for engineered algae: redirecting metabolism to fuel a biotechnology revolution. Curr Opin Biotechnol 19: 430–436. Available: http://www.ncbi.nlm.nih.gov/pubmed/18725?295. Accessed 6 August 2013.
|
[13] | Radakovits R, Jinkerson RE, Darzins A, Posewitz MC (2010) Genetic engineering of algae for enhanced biofuel production. Eukaryot Cell 9: 486–501 Available: http://www.pubmedcentral.nih.gov/article?render.fcgi?artid=2863401&tool=pmcentrez?&rendertype=abstract. Accessed 9 August 2013.
|
[14] | Georgianna DR, Mayfield SP (2012) Exploiting diversity and synthetic biology for the production of algal biofuels. Nature 488: 329–335 Available: http://www.ncbi.nlm.nih.gov/pubmed/22895?338. Accessed 8 August 2013.
|
[15] | Wijffels RH, Kruse O, Hellingwerf KJ (2013) Potential of industrial biotechnology with cyanobacteria and eukaryotic microalgae. Curr Opin Biotechnol 24: 405–413 Available: http://www.ncbi.nlm.nih.gov/pubmed/23647?970. Accessed 7 August 2013.
|
[16] | Gimpel JA, Specht EA, Georgianna DR, Mayfield SP (2013) Advances in microalgae engineering and synthetic biology applications for biofuel production. Curr Opin Chem Biol 17: 489–495 Available: http://dx.doi.org/10.1016/j.cbpa.2013.03?.038. Accessed 13 August 2013.
|
[17] | Beer LL, Boyd ES, Peters JW, Posewitz MC (2009) Engineering algae for biohydrogen and biofuel production. Curr Opin Biotechnol 20: 264–271 Available: http://www.ncbi.nlm.nih.gov/pubmed/19560?336. Accessed 7 August 2013.
|
[18] | Gong Y, Hu H, Gao Y, Xu X, Gao H (2011) Microalgae as platforms for production of recombinant proteins and valuable compounds: progress and prospects. J Ind Microbiol Biotechnol 38: 1879–1890 Available: http://www.ncbi.nlm.nih.gov/pubmed/21882?013. Accessed 6 August 2013.
|
[19] | Hannon M, Gimpel J, Tran M, Rasala B, Mayfield S (2010) Biofuels from algae: challenges and potential. Biofuels 1: 763–784 Available: http://www.pubmedcentral.nih.gov/article?render.fcgi?artid=3152439&tool=pmcentrez?&rendertype=abstract.
|
[20] | Cerutti H, Johnson AM, Gillham NW, Boynton JE (1997) Epigenetic silencing of a foreign gene in nuclear transformants of Chlamydomonas. Plant Cell 9: 925–945 Available: http://www.plantcell.org/content/9/6/925?.abstract. Accessed 27 August 2013.
|
[21] | Fuhrmann M, Oertel W, Hegemann P (1999) A synthetic gene coding for the green fluorescent protein (GFP) is a versatile reporter in Chlamydomonas reinhardtii+. Plant J 19: 353–361 Available: http://doi.wiley.com/10.1046/j.1365-313X?.1999.00526.x. Accessed 27 August 2013.
|
[22] | Neupert J, Karcher D, Bock R (2009) Generation of Chlamydomonas strains that efficiently express nuclear transgenes. Plant J 57: 1140–1150 Available: http://www.ncbi.nlm.nih.gov/pubmed/19036?032. Accessed 21 August 2013.
|
[23] | Rasala BA, Lee PA, Shen Z, Briggs SP, Mendez M, et al. (2012) Robust expression and secretion of Xylanase1 in Chlamydomonas reinhardtii by fusion to a selection gene and processing with the FMDV 2A peptide. PLoS One 7: e43349 Available: http://www.pubmedcentral.nih.gov/article?render.fcgi?artid=3427385&tool=pmcentrez?&rendertype=abstract. Accessed 30 July 2013.
|
[24] | Rasala BA, Barrera DJ, Ng J, Plucinak TM, Rosenberg JN, et al. (2013) Expanding the spectral palette of fluorescent proteins for the green microalga Chlamydomonas reinhardtii. Plant J 74: 545–556 Available: http://www.ncbi.nlm.nih.gov/pubmed/23521?393. Accessed 5 August 2013.
|
[25] | Donnelly ML, Luke G, Mehrotra A, Li X, Hughes LE, et al. (2001) Analysis of the aphthovirus 2A/2B polyprotein “cleavage” mechanism indicates not a proteolytic reaction, but a novel translational effect: a putative ribosomal “skip”. J Gen Virol 82: 1013–1025 Available: http://www.ncbi.nlm.nih.gov/pubmed/11297?676. Accessed 3 March 2014.
|
[26] | De Felipe P (2004) Skipping the co-expression problem: the new 2A “CHYSEL” technology. Genet Vaccines Ther 2: 13 Available: http://www.gvt-journal.com/content/2/1/1?3. Accessed 16 August 2013.
|
[27] | Kalderon D, Roberts BL, Richardson WD, Smith AE (1984) A short amino acid sequence able to specify nuclear location. Cell 39: 499–509 Available: http://dx.doi.org/10.1016/0092-8674(84)9?0457-4. Accessed 27 August 2013.
|
[28] | Morris GJ, Coulson GE, Leeson EA (1985) Changes in the shape of mitochondria following osmotic stress to the unicellular green alga Chlamydomonas reinhardii. J Cell Sci 76: 145–153 Available: http://www.ncbi.nlm.nih.gov/pubmed/39058?35. Accessed 27 August 2013.
|
[29] | Ehara T, Osafune T, Hase E (1995) Behavior of mitochondria in synchronized cells of Chlamydomonas reinhardtii (Chlorophyta). J Cell Sci 108 (Pt 2: 499–507 Available: http://www.ncbi.nlm.nih.gov/pubmed/77689?96. Accessed 27 August 2013.
|
[30] | Hiramatsu T, Nakamura S, Misumi O, Kuroiwa T (2006) Morphological Changes In Mitochondrial And Chloroplast Nucleoids And Mitochondria During The Chlamydomonas Reinhardtii (Chlorophyceae) Cell Cycle. J Phycol 42: 1048–1058 Available: http://doi.wiley.com/10.1111/j.1529-8817?.2006.00259.x. Accessed 27 August 2013.
|
[31] | Harris EH, Stern DB, Witman GB (2009) The Chlamydomonas Sourcebook. Second Edi. Elsevier Available: http://dx.doi.org/10.1016/B978-0-12-3708?73-1.00002-2. Accessed 28 August 2013.
|
[32] | Fischer N, Rochaix JD (2001) The flanking regions of PsaD drive efficient gene expression in the nucleus of the green alga Chlamydomonas reinhardtii. Mol Genet Genomics 265: 888–894 Available: http://www.ncbi.nlm.nih.gov/pubmed/11523?806. Accessed 27 August 2013.
|
[33] | Voeltz GK, Rolls MM, Rapoport TA (2002) Structural organization of the endoplasmic reticulum. EMBO Rep 3: 944–950 Available: http://www.pubmedcentral.nih.gov/article?render.fcgi?artid=1307613&tool=pmcentrez?&rendertype=abstract. Accessed 27 August 2013.
|
[34] | Gomord V, Denmat L-A, Fitchette-Laine A-C, Satiat-Jeunemaitre B, Hawes C, et al. (1997) The C-terminal HDEL sequence is sufficient for retention of secretory proteins in the endoplasmic reticulum (ER) but promotes vacuolar targeting of proteins that escape the ER. Plant J 11: 313–325 Available: http://doi.wiley.com/10.1046/j.1365-313X?.1997.11020313.x. Accessed 27 August 2013.
|
[35] | De Hostos EL, Togasaki RK, Grossman A (1988) Purification and biosynthesis of a derepressible periplasmic arylsulfatase from Chlamydomonas reinhardtii. J Cell Biol 106: 29–37 Available: http://www.pubmedcentral.nih.gov/article?render.fcgi?artid=2114941&tool=pmcentrez?&rendertype=abstract. Accessed 28 August 2013.
|
[36] | Schroda M (2004) The Chlamydomonas genome reveals its secrets: chaperone genes and the potential roles of their gene products in the chloroplast. Photosynth Res 82: 221–240 Available: http://www.ncbi.nlm.nih.gov/pubmed/16143?837. Accessed 28 August 2013.
|
[37] | Kim JH, Lee S-R, Li L-H, Park H-J, Park J-H, et al. (2011) High cleavage efficiency of a 2A peptide derived from porcine teschovirus-1 in human cell lines, zebrafish and mice. PLoS One 6: e18556 Available: http://dx.plos.org/10.1371/journal.pone.?0018556. Accessed 12 August 2013.
|
[38] | Fang J, Qian J-J, Yi S, Harding TC, Tu GH, et al. (2005) Stable antibody expression at therapeutic levels using the 2A peptide. Nat Biotechnol 23: 584–590 Available: http://www.ncbi.nlm.nih.gov/pubmed/15834?403. Accessed 3 February 2014.
|
[39] | Szymczak AL, Workman CJ, Wang Y, Vignali KM, Dilioglou S, et al. (2004) Correction of multi-gene deficiency in vivo using a single “self-cleaving” 2A peptide-based retroviral vector. Nat Biotechnol 22: 589–594 Available: http://www.ncbi.nlm.nih.gov/pubmed/15064?769. Accessed 20 January 2014.
|
[40] | Keasling JD (2012) Synthetic biology and the development of tools for metabolic engineering. Metab Eng 14: 189–195 Available: http://www.sciencedirect.com/science/art?icle/pii/S1096717612000055. Accessed 20 January 2014.
|
[41] | Halpin C (2005) Gene stacking in transgenic plants—the challenge for 21st century plant biotechnology. Plant Biotechnol J 3: 141–155 Available: http://www.ncbi.nlm.nih.gov/pubmed/17173?615. Accessed 23 January 2014.
|
[42] | Ha S-H, Liang YS, Jung H, Ahn M-J, Suh S-C, et al. (2010) Application of two bicistronic systems involving 2A and IRES sequences to the biosynthesis of carotenoids in rice endosperm. Plant Biotechnol J 8: 928–938 Available: http://www.ncbi.nlm.nih.gov/pubmed/20649?940. Accessed 4 February 2014.
|
[43] | Zhang F, Rodriguez S, Keasling JD (2011) Metabolic engineering of microbial pathways for advanced biofuels production. Curr Opin Biotechnol 22: 775–783 Available: http://www.sciencedirect.com/science/art?icle/pii/S0958166911000875. Accessed 20 January 2014.
|
[44] | Heinig U, Gutensohn M, Dudareva N, Aharoni A (2013) The challenges of cellular compartmentalization in plant metabolic engineering. Curr Opin Biotechnol 24: 239–246 Available: http://www.ncbi.nlm.nih.gov/pubmed/23246?154. Accessed 15 August 2013.
|
[45] | Sweetlove LJ, Fernie AR (2013) The spatial organization of metabolism within the plant cell. Annu Rev Plant Biol 64: 723–746 Available: http://www.ncbi.nlm.nih.gov/pubmed/23330?793. Accessed 13 August 2013.
|
[46] | Dumas P, Bergdoll M, Cagnon C, Masson JM (1994) Crystal structure and site-directed mutagenesis of a bleomycin resistance protein and their significance for drug sequestering. EMBO J 13: 2483–2492 Available: http://www.pubmedcentral.nih.gov/article?render.fcgi?artid=395119&tool=pmcentrez&?rendertype=abstract. Accessed 4 February 2014.
|