[1] | Black RE, Cousens S, Johnson HL, Lawn JE, Rudan I, et al. (2010) Global, regional, and national causes of child mortality in 2008: a systematic analysis. Lancet 375: 1969–1987.
|
[2] | Kotloff KL, Winickoff JP, Ivanoff B, Clemens JD, Swerdlow DL, et al. (1997) Global burden of Shigella infections: implications for vaccine development and implementation of control strategies. Bull World Health Organ 77: 651–66.
|
[3] | Peng X, Luo W, Zhang J, Wang S, Lin S (2002) Rapid detection of Shigella species in environmental sewage by an immunocapture PCR with universal primers. Appl Environ Microbiol 68: 2580–2583.
|
[4] | Paterson DL (2006) Resistance in gram-negative bacteria: Enterobacteriaceae. Am J Med 119: S20–S28.
|
[5] | Anders K, Li A, Zhao ZC, Karlsson K, Minh NB, et al. (1995) Safety and immunogenicity of the auxotrophic Shigella flexneri 2a vaccine SFL1070 with a deleted aroD gene in adult Swedish volunteers. Vaccine 13: 88–89.
|
[6] | Coster TS, Hoge CW, VanDeVerg LL, Hartman AB, Oaks EV, et al. (1999) Vaccination against shigellosis with attenuated Shigella flexneri 2a strain SC602. Infect Immun 67: 3437–3443.
|
[7] | Katz DE, Coster TS, Wolf MK, Trespalacios FC, Cohen D, et al. (2004) Two studies evaluating the safety and immunogenicity of a live, attenuated Shigella flexneri 2a vaccine (SC602) and excretion of vaccine organisms in North American volunteers. Infect Immun 72: 923–930.
|
[8] | Ranallo RT, Fonseka CP, Cassels F, Srinivasan J, Venkatesan MM (2005) Construction and characterization of bivalent Shigella flexneri 2a vaccine strains SC608(pCFAI) and SC608(pCFAI/LTB) that express antigens from enterotoxigenic Escherichia coli. Infect Immun 73: 258–267.
|
[9] | Mukhopadhaya A, Mahalanabis D, Khanam J, Chakrabarti MK (2003) Protective efficacy of oral immunization with heat-killed Shigella flexneri 2a in animal model: study of cross protection, immune response and antigenic recognition. Vaccine 21: 3043–3050.
|
[10] | Mukhopadhaya A, Mahalanabis D, Chakrabarti MK (2006) Role of Shigella flexneri 2a 34 kDa outer membrane protein in induction of protective immune response. Vaccine 24: 6028–6036.
|
[11] | Jennison AV, Verma NK (2004) Shigella flexneri infection: pathogenesis and vaccine development. FEMS Microbiol Rev 28: 43–58.
|
[12] | Kotloff KL, Simon JK, Pasetti MF, Sztein MB, Wooden SL, et al. (2007) Safety and Immunogenicity of CVD 1208S, a Live, Oral _guaBA _sen _set Shigella flexneri 2a Vaccine Grown on Animal-Free Media. Human Vaccine 3: 268–275.
|
[13] | Simon JK, Maciel M Jr, Weld ED, Wahid R, Pasetti MF, et al. (2011) Antigen-specific IgA B memory cell responses to Shigella antigens elicited in volunteers immunized with live attenuated Shigella flexneri 2a oral vaccine candidates. Clin Immunol 139: 185–192.
|
[14] | Biswas T (2000) Role of porin of Shigella dysenteriae type 1 in modulation of lipopolysaccharide mediated nitric oxide and interleukin-1 release by murine peritoneal macrophages. FEMS Immunol. Med. Microbiol. 29: 129–136.
|
[15] | Sansonetti PJ (2001) Microbes and microbial toxins: paradigms for microbial mucosal interactions III. Shigellosis: from symptoms to molecular pathogenesis. Am J Physiol Gastrointest Liver Physiol 280: G319–G323.
|
[16] | Koebnik R, Locher KP, Van Gelder P (2000) Structure and function of bacterial outer membrane proteins: barrels and nutshell. Mol Microbiol 37: 239–253.
|
[17] | Lin J, Huang S, Zhang Q (2002) Outer membrane proteins: key players for bacterial adaptation in host niches. Microbes Infect 4: 325–331.
|
[18] | Adamus G, Mulczyk M, Witkowska D, Romanowska E (1980) Protection against keratoconjunctivitis shigellosa induced by immunization with outer membrane proteins of Shigella spp. Infect Immun 30: 321–324.
|
[19] | Mulczyk M, Adamus G, Witkowska D, Romanowska E (1981) Studies on virulence of Shigella flexneri. Protective effect of outer membrane proteins. Arch Immunol Ther Exp 29: 85–90.
|
[20] | Witkowska D, Czarny A, Mulczyk M (1986) Humoral response in mice immunized with outer membrane proteins of Shigella flexneri. Arch Immunol Ther Exp 34: 499–504.
|
[21] | Witkowska D, Czarny A, Mulczyk M (1992) Humoral response in mice immunized with outer membrane proteins of Hafnia alvei. Protective activity of anti-OMP-antibodies. Arch Immunol Ther Exp 40: 301–304.
|
[22] | Witkowska D, Mleczko J, Mulczyk M (1985) Transfer of immunity by means of spleen cells from mice immunized with outer membrane proteins of Shigella flexneri. Arch Immunol Ther Exp 33: 629–635.
|
[23] | Witkowska D, Mas?owska E, Staniszewska M, Szostko B, Jankowski A, et al. (2006) Enterobacterial 38-kDa outer membrane protein is an age-dependent molecular marker of innate immunity and immunoglobulin deficiency as results from its reactivity with IgG and IgA antibody. FEMS Immunol Med Microbiol 48: 205–214.
|
[24] | Roy S, Das AB, Ghosh AN, Biswas T (1994) Purification, pore-forming ability, and antigenic relatedness of the major outer membrane protein of Shigella dysenteriae type 1. Infect Immun 62: 4333–4338.
|
[25] | Pore D, Mahata N, Pal A, Chakrabarti MK (2011) Outer membrane protein A (OmpA) of Shigella flexneri 2a, induces protective immune response in a mouse model. PLoS ONE 6(7): e22663.
|
[26] | Ying T, Wang H, Li M, Wang J, Wang J, et al. (2005) Immunoproteomics of outer membrane proteins and extracellular proteins of Shigella flexneri 2a 2457T. Proteomics 5: 4777–4793.
|
[27] | Benz I, Schmidt MA (2002) Never say never again: protein glycosylation in pathogenic bacteria. Mol Microbiol. 45: 267–276.
|
[28] | Baslé A, Rummel G, Storici P, Rosenbusch JP, Schirmer T (2006) Crystal structure of osmoporin OmpC from E. coli at 2.0 A. J Mol Biol. 362: 933–942.
|
[29] | Arnold K, Bordoli L, Kopp J, Schwede T (2006) The SWISS-MODEL Workspace: A web-based environment for protein structure homology modelling. Bioinformatics 22: 195–201.
|
[30] | Schwede T, Kopp J, Guex N, Peitsch MC (2003) SWISS-MODEL: An automated protein homology-modeling server. Nucleic Acids Res 31: 3381–3385.
|
[31] | Guex N, Peitsch MC (1997) SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. Electrophoresis 18: 2714–2723.
|
[32] | Sweredoski M, Baldi P (2008) PEPITO: improved discontinuous B-cell epitope prediction using multiple distance thresholds and half sphere exposure. Bioinformatics. 24: 1459–1460 http://pepito.proteomics.ics.uci.edu.
|
[33] | Jarz?b A, Witkowska D, Szostko B, Hirnle L, Gamian A (2011) Potential carrier for conjugate vaccines: OMP-38 protein from Shigella flexneri 3a – isolation and purification strategies. Sepsis 4: 39–45.
|
[34] | Fujita Y, Taguchi H (2011) Current status of multiple antigen-presenting peptide vaccine systems: Application of organic and inorganic nanoparticles. Chem Cent J 23 5(1): 48.
|
[35] | Wieser A, Romann E, Magistro G, Hoffmann C, N?renberg D, et al. (2010) A multiepitope subunit vaccine conveys protection against extraintestinal pathogenic Escherichia coli in mice. Infect Immun 78: 3432–3442.
|
[36] | Williams KM, Bigley EC 3rd, Raybourne RB (2000) Identification of murine B-cell and T-cell epitopes of Escherichia coli outer membrane protein F with synthetic polypeptides. Infect Immun 68: 2535–2545.
|
[37] | Borrelli S, Hossany RB, Pinto BM (2008) Immunological evidence for functional rather than structural mimicry by a Shigella flexneri Y polysaccharide-mimetic peptide. Clin Vaccine Immunol 15: 1106–1114.
|
[38] | Sesardic D (1993) Synthetic peptide vaccines. J Med Microbiol 39: 241–242.
|
[39] | Nardin E (2010) The past decade in malaria synthetic peptide vaccine clinical trials. Hum Vaccin 6: 27–38.
|
[40] | McCarty M (1973) Bacterial and mycotic infections in Davis B. D., Dulbecco R., Eisen H. N., Ginsberg H. S., Wood W. B. Jr: Microbiology, Harper and Row Publishers, Hagerstown, (M)., N. York-Evanston-San Francisco.
|
[41] | Baldridge JR, Crane RT (1999) Monophosphoryl Lipid A (MPL) Formulations for the Next Generation of Vaccines. Methods 19: 103–107.
|
[42] | Arcidiacono S, Butler MM, Mello CM (2002) A rapid selective extraction procedure for the outer membrane protein (OmpF) from Escherichia coli. Protein Expr Purif 25: 134–137.
|
[43] | Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the folin phenol reagent. J Biol Chem 193: 265–275.
|
[44] | Laemmli UK (1970) Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature 277: 680–685.
|
[45] | Shevchenko A, Wilm M, Vorm O, Mann M (1996) Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem 68: 850–858.
|
[46] | Gharahdaghi F, Weinberg CR, Meagher DA, Imai BS, Mische SM (1999) Mass spectrometric identification of proteins from silver-stained polyacrylamide gel: a method for the removal of silver ions to enhance sensitivity. Electrophoresis. 20: 601–605.
|
[47] | Carter JM (1994) Epitope mapping of a protein using the Geysen (PEPSCAN) procedure. Methods Mol Biol 36: 207–223.
|