| [1] | Newby AC, Zaltsman AB (2000) Molecular mechanisms in intimal hyperplasia. J Pathol 190: 300-309. doi:10.1002/(SICI)1096-9896(200002)190:3. PubMed: 10685064.
|
| [2] | Swirski FK, Nahrendorf M, Etzrodt M, Wildgruber M, Cortez-Retamozo V et al. (2009) Identification of splenic reservoir monocytes and their deployment to inflammatory sites. Science 325: 612-616. doi:10.1126/science.1175202. PubMed: 19644120.
|
| [3] | Tedgui A, Mallat Z (2001) Anti-inflammatory mechanisms in the vascular wall. Circ Res 88: 877-887. doi:10.1161/hh0901.090440. PubMed: 11348996.
|
| [4] | Wen JK, Han M, Zheng B, Yang SL (2002) Comparison of gene expression patterns and migration capability at quiescent and proliferating vascular smooth muscle cells stimulated by cytokines. Life Sci 70: 799-807. doi:10.1016/S0024-3205(01)01446-1. PubMed: 11833742.
|
| [5] | Hansson GK (2005) Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 352: 1685-1695. doi:10.1056/NEJMra043430. PubMed: 15843671.
|
| [6] | Chen S, Ding Y, Tao W, Zhang W, Liang T et al. (2012) Naringenin inhibits TNF-alpha induced VSMC proliferation and migration via induction of HO-1. Food Chem Toxicol 50: 3025-3031. doi:10.1016/j.fct.2012.06.006. PubMed: 22709785.
|
| [7] | Moe SM, Chen NX (2004) Pathophysiology of vascular calcification in chronic kidney disease. Circ Res 95: 560-567. doi:10.1161/01.RES.0000141775.67189.98. PubMed: 15375022.
|
| [8] | Rogers PA, Abberton KM (2003) Endometrial arteriogenesis: vascular smooth muscle cell proliferation and differentiation during the menstrual cycle and changes associated with endometrial bleeding disorders. Microsc Res Tech 60: 412-419. doi:10.1002/jemt.10279. PubMed: 12567398.
|
| [9] | Yang X, Thomas DP, Zhang X, Culver BW, Alexander BM et al. (2006) Curcumin inhibits platelet-derived growth factor-stimulated vascular smooth muscle cell function and injury-induced neointima formation. Arterioscler Thromb Vasc Biol 26: 85-90. doi:10.1161/01.ATV.0000191635.00744.b6. PubMed: 16239599.
|
| [10] | Tian JS, Cui YL, Hu LM, Gao S, Chi W et al. (2010) Antidepressant-like effect of genipin in mice. Neurosci Lett 479: 236-239. doi:10.1016/j.neulet.2010.05.069. PubMed: 20561935.
|
| [11] | Lee JH, Lee DU, Jeong CS (2009) Gardenia Jasminoides Ellis ethanol extract and its constituents reduce the risks of gastritis and reverse gastric lesions in rats. Food Chem Toxicol 47: 1127-1131. doi:10.1016/j.fct.2009.01.037. PubMed: 19425231.
|
| [12] | Zhang CY, Parton LE, Ye CP, Krauss S, Shen R et al. (2006) Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced beta cell dysfunction in isolated pancreatic islets. Cell Metab 3: 417-427. doi:10.1016/j.cmet.2006.04.010. PubMed: 16753577.
|
| [13] | Nam KN, Choi YS, Jung HJ, Park GH, Park JM et al. (2010) Genipin inhibits the inflammatory response of rat brain microglial cells. Int Immunopharmacol 10: 493-499. doi:10.1016/j.intimp.2010.01.011. PubMed: 20123040.
|
| [14] | Wang GF, Wu SY, Rao JJ, Lü L, Xu W et al. (2009) Genipin inhibits endothelial exocytosis via nitric oxide in cultured human umbilical vein endothelial cells. Acta Pharmacol Sin 30: 589-596. doi:10.1038/aps.2009.31. PubMed: 19349964.
|
| [15] | Tanaka M, Yamazaki M, Chiba K (2009) Neuroprotective action of genipin on tunicamycin-induced cytotoxicity in neuro2a cells. Biol Pharm Bull 32: 1220-1223. doi:10.1248/bpb.32.1220. PubMed: 19571389.
|
| [16] | Kondo K, Suzuki Y, Ikeda Y, Umemura K (2002) Genistein, an isoflavone included in soy, inhibits thrombotic vessel occlusion in the mouse femoral artery and in vitro platelet aggregation. Eur J Pharmacol 455: 53-57. doi:10.1016/S0014-2999(02)02449-4. PubMed: 12433594.
|
| [17] | Tenhunen R, Marver HS, Schmid R (1968) The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc Natl Acad Sci U S A 61: 748-755. doi:10.1073/pnas.61.2.748. PubMed: 4386763.
|
| [18] | Duckers HJ, Boehm M, True AL, Yet SF, San H et al. (2001) Heme oxygenase-1 protects against vascular constriction and proliferation. Nat Med 7: 693-698. doi:10.1038/89068. PubMed: 11385506.
|
| [19] | Zhang M, Zhang BH, Chen L, An W (2002) Overexpression of heme oxygenase-1 protects smooth muscle cells against oxidative injury and inhibits cell proliferation. Cell Res 12: 123-132. doi:10.1038/sj.cr.7290118. PubMed: 12118938.
|
| [20] | Kim JE, Kang YJ, Lee KY, Choi HC (2009) Isoproterenol inhibits angiotensin II-stimulated proliferation and reactive oxygen species production in vascular smooth muscle cells through heme oxygenase-1. Biol Pharm Bull 32: 1047-1052. doi:10.1248/bpb.32.1047. PubMed: 19483313.
|
| [21] | Jeon WK, Hong HY, Kim BC (2011) Genipin up-regulates heme oxygenase-1 via PI3-kinase-JNK1/2-Nrf2 signaling pathway to enhance the anti-inflammatory capacity in RAW264.7 macrophages. Arch Biochem Biophys 512: 119-125. doi:10.1016/j.abb.2011.05.016. PubMed: 21658364.
|
| [22] | Sherr CJ (1996) Cancer cell cycles. Science 274: 1672-1677. doi:10.1126/science.274.5293.1672. PubMed: 8939849.
|
| [23] | Abukhdeir AM, Park BH (2008) P21 and p27: roles in carcinogenesis and drug resistance. Expert Rev Mol Med 10: e19. doi:10.1017/S1462399408000744. PubMed: 18590585.
|
| [24] | Sprague AH, Khalil RA (2009) Inflammatory cytokines in vascular dysfunction and vascular disease. Biochem Pharmacol 78: 539-552. doi:10.1016/j.bcp.2009.04.029. PubMed: 19413999.
|
| [25] | Chandrashekhar Y, Sen S, Anway R, Shuros A, Anand I (2004) Long-term caspase inhibition ameliorates apoptosis, reduces myocardial troponin-I cleavage, protects left ventricular function, and attenuates remodeling in rats with myocardial infarction. J Am Coll Cardiol 43: 295-301. doi:10.1016/S0735-1097(04)91250-8. PubMed: 14736452.
|
| [26] | Dugourd C, Gervais M, Corvol P, Monnot C (2003) Akt is a major downstream target of PI3-kinase involved in angiotensin II-induced proliferation. Hypertension 41: 882-890. doi:10.1161/01.HYP.0000060821.62417.35. PubMed: 12623864.
|
| [27] | Gong DW, He Y, Karas M, Reitman M (1997) Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, beta3-adrenergic agonists, and leptin. J Biol Chem 272: 24129-24132. doi:10.1074/jbc.272.39.24129. PubMed: 9305858.
|
| [28] | Mizuno T, Miura-Suzuki T, Yamashita H, Mori N (2000) Distinct regulation of brain mitochondrial carrier protein-1 and uncoupling protein-2 genes in the rat brain during cold exposure and aging. Biochem Biophys Res Commun 278: 691-697. doi:10.1006/bbrc.2000.3859. PubMed: 11095970.
|
| [29] | Ricquier D, Bouillaud F (2000) The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP. Biochem J 345 2: 161-179. doi:10.1042/0264-6021:3450161. PubMed: 10620491.
|
| [30] | Haines BA, Mehta SL, Pratt SM, Warden CH, Li PA (2010) Deletion of mitochondrial uncoupling protein-2 increases ischemic brain damage after transient focal ischemia by altering gene expression patterns and enhancing inflammatory cytokines. J Cereb Blood Flow Metab 30: 1825-1833. doi:10.1038/jcbfm.2010.52. PubMed: 20407461.
|
| [31] | Bo H, Jiang N, Ma G, Qu J, Zhang G et al. (2008) Regulation of mitochondrial uncoupling respiration during exercise in rat heart: role of reactive oxygen species (ROS) and uncoupling protein 2. Free Radic Biol Med 44: 1373-1381. doi:10.1016/j.freeradbiomed.2007.12.033. PubMed: 18226608.
|
| [32] | Brand MD, Affourtit C, Esteves TC, Green K, Lambert AJ et al. (2004) Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins. Free Radic Biol Med 37: 755-767. doi:10.1016/j.freeradbiomed.2004.05.034. PubMed: 15304252.
|
| [33] | Jezek P (2002) Possible physiological roles of mitochondrial uncoupling proteins--UCPn. Int J Biochem Cell Biol 34: 1190-1206. doi:10.1016/S1357-2725(02)00061-4. PubMed: 12127570.
|
| [34] | Kim HS, Park KG, Koo TB, Huh S, Lee IK (2007) The modulating effects of the overexpression of uncoupling protein 2 on the formation of reactive oxygen species in vascular cells. Diabetes Res Clin Pract 77 Suppl 1: S46-S48. doi:10.1016/j.diabres.2007.01.032. PubMed: 17462780.
|
| [35] | Pak O, Sommer N, Hoeres T, Bakr A, Waisbrod S et al. (2013) Mitochondrial Hyperpolarization in Pulmonary Vascular Remodeling - UCP2 Deficiency as Disease Model. Am J Respir Cell Mol Biol. PubMed: 23590303.
|
| [36] | Mu J, Pinkstaff J, Li Z, Skidmore L, Li N et al. (2012) FGF21 analogs of sustained action enabled by orthogonal biosynthesis demonstrate enhanced antidiabetic pharmacology in rodents. Diabetes 61: 505-512. doi:10.2337/db11-0838. PubMed: 22210323.
|
