| [1] | Hirokawa N, Niwa S, Tanaka Y (2010) Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease. Neuron 68: 610-638. doi:10.1016/j.neuron.2010.09.039. PubMed: 21092854.
|
| [2] | Setou M, Seog DH, Tanaka Y, Kanai Y, Takei Y et al. (2002) Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites. Nature 417: 83-87. doi:10.1038/nature743. PubMed: 11986669.
|
| [3] | Kapitein LC, Schlager MA, Kuijpers M, Wulf PS, van Spronsen M et al. (2010) Mixed microtubules steer dynein-driven cargo transport into dendrites. Curr Biol 20: 290-299. doi:10.1016/j.cub.2009.12.052. PubMed: 20137950.
|
| [4] | Westermann S, Weber K (2003) Post-translational modifications regulate microtubule function. Nat Rev Mol Cell Biol 4: 938-947. doi:10.1038/nrm1260. PubMed: 14685172.
|
| [5] | Janke C, Kneussel M (2010) Tubulin post-translational modifications: encoding functions on the neuronal microtubule cytoskeleton. Trends Neurosci, 33: 362–72. PubMed: 20541813.
|
| [6] | Maas C, Belgardt D, Lee HK, Heisler FF, Lappe-Siefke C et al. (2009) Synaptic activation modifies microtubules underlying transport of postsynaptic cargo. Proc Natl Acad Sci U S A 106: 8731-8736. doi:10.1073/pnas.0812391106. PubMed: 19439658.
|
| [7] | Dompierre JP, Godin JD, Charrin BC, Cordelières FP, King SJ et al. (2007) Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington’s disease by increasing tubulin acetylation. J Neurosci 27: 3571-3583. doi:10.1523/JNEUROSCI.0037-07.2007. PubMed: 17392473.
|
| [8] | Ikegami K, Heier RL, Taruishi M, Takagi H, Mukai M et al. (2007) Loss of alpha-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulated synaptic function. Proc Natl Acad Sci U S A 104: 3213-3218. doi:10.1073/pnas.0611547104. PubMed: 17360631.
|
| [9] | Guillaud L, Wong R, Hirokawa N (2008) Disruption of KIF17-Mint1 interaction by CaMKII-dependent phosphorylation: a molecular model of kinesin-cargo release. Nat Cell Biol 10: 19-29. doi:10.1038/ncb1665. PubMed: 18066053.
|
| [10] | Verhey KJ, Hammond JW (2009) Traffic control: regulation of kinesin motors. Nat Rev Mol Cell Biol 10: 765-777. doi:10.1038/nrm2782. PubMed: 19851335.
|
| [11] | Marszalek JR, Weiner JA, Farlow SJ, Chun J, Goldstein LS (1999) Novel dendritic kinesin sorting identified by different process targeting of two related kinesins: KIF21A and KIF21B. J Cell Biol 145: 469-479. doi:10.1083/jcb.145.3.469. PubMed: 10225949.
|
| [12] | Baas PW, Deitch JS, Black MM, Banker GA (1988) Polarity orientation of microtubules in hippocampal neurons: uniformity in the axon and nonuniformity in the dendrite. Proc Natl Acad Sci U S A 85: 8335-8339. doi:10.1073/pnas.85.21.8335. PubMed: 3054884.
|
| [13] | International Multiple Sclerosis Genetics Consortium (IMSGC) (2010) Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci. Hum Mol Genet 19: 953-962. doi:10.1093/hmg/ddp542. PubMed: 20007504.
|
| [14] | Goris A, Boonen S, D’Hooghe MB, Dubois B (2010) Replication of KIF21B as a susceptibility locus for multiple sclerosis. J Med Genet 47: 775-776. doi:10.1136/jmg.2009.075911. PubMed: 20587413.
|
| [15] | Franke A, Balschun T, Karlsen TH, Hedderich J, May S et al. (2008) Replication of signals from recent studies of Crohn’s disease identifies previously unknown disease loci for ulcerative colitis. Nat Genet 40: 713-715. doi:10.1038/ng.148. PubMed: 18438405.
|
| [16] | Danoy P, Pryce K, Hadler J, Bradbury LA, Farrar C et al. (2010) Association of variants at 1q32 and STAT3 with ankylosing spondylitis suggests genetic overlap with Crohn’s disease. PLOS Genet 6: e1001195. PubMed: 21152001.
|
| [17] | Napolitano LM, Meroni G (2012) TRIM family: Pleiotropy and diversification through homomultimer and heteromultimer formation. IUBMB Life 64: 64-71. doi:10.1002/iub.580. PubMed: 22131136.
|
| [18] | Napolitano LM, Jaffray EG, Hay RT, Meroni G (2011) Functional interactions between ubiquitin E2 enzymes and TRIM proteins. Biochem J 434: 309-319. doi:10.1042/BJ20101487. PubMed: 21143188.
|
| [19] | Ozato K, Shin DM, Chang TH, Morse HC 3rd (2008) TRIM family proteins and their emerging roles in innate immunity. Nat Rev Immunol 8: 849-860. doi:10.1038/nri2413. PubMed: 18836477.
|
| [20] | Hung AY, Sung CC, Brito IL, Sheng M (2010) Degradation of postsynaptic scaffold GKAP and regulation of dendritic spine morphology by the TRIM3 ubiquitin ligase in rat hippocampal neurons. PLOS ONE 5: e9842. doi:10.1371/journal.pone.0009842. PubMed: 20352094.
|
| [21] | Chu Y, Yang X (2011) SUMO E3 ligase activity of TRIM proteins. Oncogene 30: 1108-1116. doi:10.1038/onc.2010.462. PubMed: 20972456.
|
| [22] | Shin SM, Zhang N, Hansen J, Gerges NZ, Pak DT et al. (2012) GKAP orchestrates activity-dependent postsynaptic protein remodeling and homeostatic scaling. Nat Neurosci 15: 1655-1666. doi:10.1038/nn.3259. PubMed: 23143515.
|
| [23] | El-Husseini AE, Vincent SR (1999) Cloning and characterization of a novel RING finger protein that interacts with class V myosins. J Biol Chem 274: 19771-19777. doi:10.1074/jbc.274.28.19771. PubMed: 10391919.
|
| [24] | El-Husseini AE, Kwasnicka D, Yamada T, Hirohashi S, Vincent SR (2000) BERP, a novel ring finger protein, binds to alpha-actinin-4. Biochem Biophys Res Commun 267: 906-911. doi:10.1006/bbrc.1999.2045. PubMed: 10673389.
|
| [25] | Yan Q, Sun W, Kujala P, Lotfi Y, Vida TA et al. (2005) CART: an Hrs/actinin-4/BERP/myosin V protein complex required for efficient receptor recycling. Mol Biol Cell 16: 2470-2482. doi:10.1091/mbc.E04-11-1014. PubMed: 15772161.
|
| [26] | Cheung CC, Yang C, Berger T, Zaugg K, Reilly P et al. (2010) Identification of BERP (brain-expressed RING finger protein) as a p53 target gene that modulates seizure susceptibility through interacting with GABA(A) receptors. Proc Natl Acad Sci U S A 107: 11883-11888. doi:10.1073/pnas.1006529107. PubMed: 20543135.
|
| [27] | Plechanovová A, Jaffray EG, Tatham MH, Naismith JH, Hay RT (2012) Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis. Nature 489: 115-120. doi:10.1038/nature11376. PubMed: 22842904.
|
| [28] | Rexach MF, Latterich M, Schekman RW (1994) Characteristics of endoplasmic reticulum-derived transport vesicles. J Cell Biol 126: 1133-1148. doi:10.1083/jcb.126.5.1133. PubMed: 8063853.
|
| [29] | Rodríguez CI, Buchholz F, Galloway J, Sequerra R, Kasper J et al. (2000) High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP. Nat Genet 25: 139-140. doi:10.1038/75973. PubMed: 10835623.
|
| [30] | Schwenk F, Baron U, Rajewsky K (1995) A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells. Nucleic Acids Res 23: 5080-5081. doi:10.1093/nar/23.24.5080. PubMed: 8559668.
|
| [31] | Ying H, Shen X, Park B, Yue BY (2010) Posttranslational modifications, localization, and protein interactions of optineurin, the product of a glaucoma gene. PLOS ONE 5: e9168. doi:10.1371/journal.pone.0009168. PubMed: 20161783.
|
| [32] | Guruprasad K, Reddy BV, Pandit MW (1990) Correlation between stability of a protein and its dipeptide composition: a novel approach for predicting in vivo stability of a protein from its primary sequence. Protein Eng 4: 155-161. doi:10.1093/protein/4.2.155. PubMed: 2075190.
|
| [33] | Kanai Y, Dohmae N, Hirokawa N (2004) Kinesin transports RNA: isolation and characterization of an RNA-transporting granule. Neuron 43: 513-525. doi:10.1016/j.neuron.2004.07.022. PubMed: 15312650.
|
| [34] | Rieser E, Cordier SM, Walczak H (2013) Linear ubiquitination: a newly discovered regulator of cell signalling. Trends Biochem Sci 38: 94-102. doi:10.1016/j.tibs.2012.11.007. PubMed: 23333406.
|
| [35] | Hirokawa N, Takemura R (2004) Kinesin superfamily proteins and their various functions and dynamics. Exp Cell Res 301: 50-59. doi:10.1016/j.yexcr.2004.08.010. PubMed: 15501445.
|
| [36] | Huang CJ, Huang CC, Chang CC (2012) Association of the testis-specific TRIM/RBCC protein RNF33/TRIM60 with the cytoplasmic motor proteins KIF3A and KIF3B. Mol Cell Biochem 360: 121-131. doi:10.1007/s11010-011-1050-8. PubMed: 21909995.
|
| [37] | Heisler FF, Loebrich S, Pechmann Y, Maier N, Zivkovic AR et al. (2011) Muskelin regulates actin filament- and microtubule-based GABA(A) receptor transport in neurons. Neuron 70: 66-81. doi:10.1016/j.neuron.2011.03.008. PubMed: 21482357.
|
| [38] | Mosesson Y, Chetrit D, Schley L, Berghoff J, Ziv T et al. (2009) Monoubiquitinylation regulates endosomal localization of Lst2, a negative regulator of EGF receptor signaling. Dev Cell 16: 687-698. doi:10.1016/j.devcel.2009.03.015. PubMed: 19460345.
|
| [39] | Hoepfner S, Severin F, Cabezas A, Habermann B, Runge A et al. (2005) Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B. Cell 121: 437-450. doi:10.1016/j.cell.2005.02.017. PubMed: 15882625.
|
| [40] | Friedman DS, Vale RD (1999) Single-molecule analysis of kinesin motility reveals regulation by the cargo-binding tail domain. Nat Cell Biol 1: 293-297. doi:10.1038/13008. PubMed: 10559942.
|
| [41] | Sun F, Zhu C, Dixit R, Cavalli V (2011) Sunday Driver/JIP3 binds kinesin heavy chain directly and enhances its motility. EMBO J 30: 3416-3429. doi:10.1038/emboj.2011.229. PubMed: 21750526.
|
| [42] | Loiseau P, Davies T, Williams LS, Mishima M, Palacios IM (2010) Drosophila PAT1 is required for Kinesin-1 to transport cargo and to maximize its motility. Development 137: 2763-2772. doi:10.1242/dev.048108. PubMed: 20630947.
|
| [43] | Cho KI, Yi H, Desai R, Hand AR, Haas AL et al. (2009) RANBP2 is an allosteric activator of the conventional kinesin-1 motor protein, KIF5B, in a minimal cell-free system. EMBO Rep 10: 480-486. doi:10.1038/embor.2009.29. PubMed: 19305391.
|
| [44] | Colin E, Zala D, Liot G, Rangone H, Borrell-Pagès M et al. (2008) Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons. EMBO J 27: 2124-2134. doi:10.1038/emboj.2008.133. PubMed: 18615096.
|
| [45] | Fuhrmann JC, Kins S, Rostaing P, El Far O, Kirsch J et al. (2002) Gephyrin interacts with Dynein light chains 1 and 2, components of motor protein complexes. J Neurosci 22: 5393-5402. PubMed: 12097491.
|
| [46] | Mandelkow EM, Stamer K, Vogel R, Thies E, Mandelkow E (2003) Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses. Neurobiol Aging 24: 1079-1085. doi:10.1016/j.neurobiolaging.2003.04.007. PubMed: 14643379.
|
