[1] | Styer KL, Singh V, Macosko E, Steele SE, Bargmann CI, et al. (2008) Innate immunity in Caenorhabditis elegans is regulated by neurons expressing NPR-1/GPCR. Science 322: 460–464. doi: 10.1126/science.1163673
|
[2] | Sun J, Singh V, Kajino-Sakamoto R, Aballay A (2011) Neuronal GPCR controls innate immunity by regulating noncanonical unfolded protein response genes. Science 332: 729–732. doi: 10.1126/science.1203411
|
[3] | Reddy KC, Andersen EC, Kruglyak L, Kim DH (2009) A polymorphism in npr-1 is a behavioral determinant of pathogen susceptibility in C. elegans. Science 323: 382–384. doi: 10.1126/science.1166527
|
[4] | Sun J, Liu Y, Aballay A (2012) Organismal regulation of XBP-1-mediated unfolded protein response during development and immune activation. EMBO Rep 13: 855–860. doi: 10.1038/embor.2012.100
|
[5] | Singh V, Aballay A (2012) Endoplasmic reticulum stress pathway required for immune homeostasis is neurally controlled by arrestin-1. J Biol Chem 287: 33191–33197. doi: 10.1074/jbc.m112.398362
|
[6] | Pradel E, Zhang Y, Pujol N, Matsuyama T, Bargmann CI, et al. (2007) Detection and avoidance of a natural product from the pathogenic bacterium Serratia marcescens by Caenorhabditis elegans. Proc Natl Acad Sci U S A 104: 2295–2300. doi: 10.1073/pnas.0610281104
|
[7] | Zhang Y, Lu H, Bargmann CI (2005) Pathogenic bacteria induce aversive olfactory learning in Caenorhabditis elegans. Nature 438: 179–184. doi: 10.1038/nature04216
|
[8] | Anyanful A, Easley KA, Benian GM, Kalman D (2009) Conditioning protects C. elegans from lethal effects of enteropathogenic E. coli by activating genes that regulate lifespan and innate immunity. Cell Host Microbe 5: 450–462. doi: 10.1016/j.chom.2009.04.012
|
[9] | Kawli T, Tan M-W (2008) Neuroendocrine signals modulate the innate immunity of Caenorhabditis elegans through insulin signaling. Nat Immunol 9: 1415–1424. doi: 10.1038/ni.1672
|
[10] | Evans EA, Kawli T, Tan M-W (2008) Pseudomonas aeruginosa suppresses host immunity by activating the DAF-2 insulin-like signaling pathway in Caenorhabditis elegans. PLoS Pathog 4: e1000175 doi:10.1371/journal.ppat.1000175.
|
[11] | Zugasti O, Ewbank JJ (2009) Neuroimmune regulation of antimicrobial peptide expression by a noncanonical TGF-beta signaling pathway in Caenorhabditis elegans epidermis. Nat Immunol 10: 249–256. doi: 10.1038/ni.1700
|
[12] | Bischof LJ, Kao C-Y, Los FC, Gonzalez MR, Shen Z, et al. (2008) Activation of the unfolded protein response is required for defenses against bacterial pore-forming toxin in vivo. PLoS Pathog 4: e1000176 doi:10.1371/journal.ppat.1000176.
|
[13] | Richardson CE, Kooistra T, Kim DH (2010) An essential role for XBP-1 in host protection against immune activation in C. elegans. Nature 463: 1092–1095. doi: 10.1038/nature08762
|
[14] | Richardson CE, Kinkel S, Kim DH (2011) Physiological IRE-1-XBP-1 and PEK-1 signaling in Caenorhabditis elegans larval development and immunity. PLoS Genet 7: e1002391 doi:10.1371/journal.pgen.1002391.
|
[15] | Haskins KA, Russell JF, Gaddis N, Dressman HK, Aballay A (2008) Unfolded protein response genes regulated by CED-1 are required for Caenorhabditis elegans innate immunity. Dev Cell 15: 87–97. doi: 10.1016/j.devcel.2008.05.006
|
[16] | Urano F, Calfon M, Yoneda T, Yun C, Kiraly M, et al. (2002) A survival pathway for Caenorhabditis elegans with a blocked unfolded protein response. J Cell Biol 158: 639–646. doi: 10.1083/jcb.200203086
|