Objectives: Evaluation of the effects
of withholding plasma during the initial part of the burn shock period (the
shock period in the study is estimated as the first 36 hours following the
burns) when it will be lost into the interstitial tissues through the permeable
capillaries. During that time crystalloids are administered. Another objective
is to evaluate the effect of administering normal saline as the crystalloid
resuscitation fluid during the initial part of the shock period.Design: A Retrospective 4 years study compares the use of normal saline as the
resuscitative intravenous fluid during the first 12 hours post burns followed
by intravenous 5% Purified Plasma Protein Fraction (PPPF) during the rest of
the shock period i.e. the remaining
24 hours, with the use of the PPPF throughout the burns shock period according
to Muir and Barclay formula. Setting: The Plastic Surgery Department and the Department of Laboratory, Directorate
General of Khoula Tertiary Hospital, Muscat, Sultanate of Oman. Patients and Methods: The study
included 2 groups of patients; Group
A: Patients who received 5% Plasma (Human PPPF) throughout the shock period and
Group B: Patients who received crystalloids in the form of normal saline during
the first 12 hours post burn followed by plasma for the next 24 hours.
Monitoring of the patients in both groups was done by using clinical signs of
pulse, blood pressure, temperature and urine output and by using laboratory
investigations in the form of the haematocrit value, sodium, potassium,
chloride, total proteins and albumin levels in the blood at the time of
admission and at the end of the shock period. Results: 140
patients were included in the study; 64 in Group A and 76 in Group B. There was
no mortality and the vital signs were maintained during the shock period in
both groups. The mean values of urine output were nearer to the normal level in
Group B compared to Group A. The same was observed
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