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Bone Marrow Micrometastases in Breast Cancer Patients: A Long-Term Follow-up Study

Keywords: bone marrow , breast cancer , long-term follow-up , micrometastases

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In 125 early breast cancer patients who underwent multiple bone marrow aspirates, there was no significant difference in terms of disease-free and overall survival after a median follow-up of 163 months between the patients with or without micrometastasis at the time of primary surgery. However, when the time-dependent evolution of the bone marrow aspirates was taken into account, some evidence for a longer disease-free and overall survival was found for the patients with negative bone marrow.


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