Hemophagocytic Syndrome Associated with Bacterial Infections

Hemophagocytic lymphohistiocytosis (HLH) is characterized by systemic proliferation and activation of benign histiocytes showing hemophagocytosis. It can be classified as primary and secondary or acquired HLH. Secondary HLH is associated with several infections, autoimmune diseases and malignancies. Here we report three cases of hemophagocytic syndrome (HS) associated with diverse bacterial infections that resolved with appropriate antibacterial therapy.