A Case of Kawasaki Disease Presenting with Aseptic Meningitis

Early recognition and prompt treatment of Kawasaki disease(KD) are essential to ensure a succesful outcome of the coronary artery involvement. However, some patients lack sufficient clinical signs to fulfill the diagnostic criteria, and this may lead to problems in diagnosing children presenting with atypical symptoms. Central nervous system involvement, including aseptic meningitis, can be a presenting feature of KD itself. In this article, we describe a 9-year-old boy who presented with an unusual onset of disease, characterized by fever, erythematous maculopapular rash, vomiting and abdominal pain. He was diagnosed as aseptic meningitis with an unusual onset of Kawasaki Disease (KD) clinical pattern together with the echocardiographic coronary arteries anomalies. Since the cardiovascular sequelaes of the disease could be prevented by early diagnosis and effective drug therapy, KD should be considered in the differential diagnosis in children with fever, erythematous maculopapular rash and vomiting that may be associated with clinical features of aseptic meningitis.