AMINOFILINA INALATóRIA E ENDOVENOSA EM C ES: ASPECTOS CLíNICO E ELETROCARDIOGRáFICO

The aim of this study was to evaluate and compare the effects of aminophylline in dogs by intravenous andinhaled administration through check heart rate, respiratory rate, rectal temperature, systolic blood pressure and heart rate via electrocardiogram. Twelve dogs were distributed in two groups: group AE- received 10mg/kg intravenous aminophylline; group AI-received aminophylline inhaled through the nebulizer at a dose of 10mg/kg, diluted in 5ml of sodium chloride solution 0,9%. We evaluated the rectal temperature (RT), heart rate (HR), respiratory rate (RR), systolic blood pressure (SBP) and electrocardiogram (ECG) at the time prior to drug administration, 30 minutes and 2, 6 and 8 hours after use of it. The average heart rate, TR faith that remained in the normal range for the species. However, some animals, both AE and AI group showed a slight increase in HR, RR and TR. The mean SBP was below the reference values in the AE group M6 and M30 and M8 in group AI. Sinus tachycardia was observed in both groups, earlier in the group AE. We conclude that intravenous aminophylline used both inhaled and causes clinical and electrocardiographic changes in dogs with a tendency to decrease systolic blood pressure, increased respiratory rate and rectal temperature as well as cardiac stimulation with increased heart rate and arrhythmia in the presence ofb animals the two groups with higher early manifestation of clinical signs in animals that received intravenous aminophylline.