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This special journal issue presents selected best software related papers from the 2010 International Conference on Frontiers of Manufacturing and Design Science (ICFMD2010) held during December 11-12, 2010. This special issue is to communicate the latest progress and research results of new theory, mew method, technology and so on in Software and Information Science, and to grasp the updated research trends in international, which will drive international communication and cooperation of production, education and research in this field. In the first papers of this special issue, “Research on Fuzzy Extension Synthesis Metrics Algorithm for Software Quality” discusses the shortages and defects caused by original fuzzy synthesis evaluation algorithm and multilayer matter-element extension evaluation algorithm based on the requirements and characteristics of software quality synthetical evaluation. “Item Relational Structure Algorithm Based on Empirical Distribution Critical Value” provide an improved threshold limit value by using the empirical distribution critical value of all the values of the relational structure indices between any two items, it is more sensitive and effective than the traditional fixed threshold for comparing the ordering relation of any two items. “Software Defect Prediction Using Non-Negative Matrix Factorization” propose a novel approach to resolve the problem of software defect prediction. The method is classification using Non-Negative Matrix Factorization (NMF). In this paper, NMF algorithm is not only used for extracting external features but also as a powerful way for classification of software defect data. “An Efficient Mining Algorithm by Bit Vector Table for Frequent Closed Itemsets” proposes an efficient mining algorithm (denoted as EMAFCI) for frequent closed itemsets in data stream. “Research of the Real-time Drawing System Based on 3D Movement Tracker” is to utilize VC++ and OpenGL to build up a real-time drawing system based on 3D movement tracker—Polhemus Fastrak. Using the method of combining programming of Microsoft Basic Class(MFC) and OpenGL to create drawing window and connect Polhemus Fastrak, the real-time drawing system has been made. “Algorithm Research on Virtual Individualized 3D Mannequin” presents a new approach for the research of virtual individualized 3D mannequin. “Use AI Technology to Analyse Corporate Goods Price Index” takes advantage of AI technique (data mining) to analyse the dataset of Corporate Goods Price Index (simple for CGPI). The public-use dataset from Chinese Bank is used in this resea