Lipid Profile in Chronic Renal Failure Patients on Dialysis

ABSTRACTThe incidence of chronic renal failure (CRF) is on the increase in Nigeria. This study on the effect of CRF on lipid profile is carried out in CRF patients on dialysis treatment. A total of 100 subjects (both male and female) were used for the study. 50 of them were apparently healthy, while the remaining 50 were CRF patients on dialysis. The levels of triglyceride (TG), total cholesterol (TC), high density lipoprotein – cholesterol (HDL-C), low density lipoprotein- cholesterol (LDL-C) and very low density lipoprotein –cholesterol (VLDL-L) were estimated using enzymatic methods. Their cardiovascular risk indices (TC/HDL-C and LDL-C/HDL-C) were also determined.The results indicated that all the parameters were significantly (p<0.05) altered in both sexes when compared with their counterparts in the control group. The cardiovascular risk indices, TC/HDL-C and LDL-C/HDL-C of the CRF patients were higher than those of the control group.In conclusion, the CRF patients on dialysis are at risk of developing cardiovascular disease.