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A Common Approach to the Synthesis of Monocyclofarnesyl SesquiterpenesKeywords: Baeyer-Villiger reaction , monocyclofarnesyl , sesquiterpenes , aplysistatin , ambilol , 7-hydroxy-6 , 11-cyclofarnes-3(15)-en-2-one , ancistrofuran , synthesis Abstract: 3beta-hydroxy-4,4,10beta-trimethyl-9-decalone and its dehydroxy analogue are useful intermediates whose Baeyer-Villiger oxidation and subsequent two-carbon homologation provides a quick entry into the monocyclofarnesyl skeleton. The synthetic approaches to a variety of sesquiterpenes are discussed.
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