Breast cancer tumor markers

Breast cancer is one of the most common cancer in women, presented with a lump and skin colour change, is one of thecommonest cancer in women. A wide variety of tumor markers viz. uPA, BRCA1 & 2, Ki76, ER, PR, HER etc. are usedfor establishing carcinoma of breast but none being a proper diagnostic tool for early detection, though each one has itsown prognostic value. Though proposed but only few are used in clinical practice, research studies are still ongoing toidentify and establish new biochemical parameters/markers that can be of used not only in advanced disease, but also inearly stages of the diagnostic workup of breast cancer.