Editorial : A Single Observation can Change a Paradigm

Medical and other scientific literature follow a peculiar repetitive pattern in their (r)evolution. They begin with an a concept (or a case) which forces us to think and deliberate on it. Be it the famous ‘Apple fall’ leading to proposal of gravity or unexpected growth of mould leading to discovery of Penicillin. Such happenings occur and define a turning point, which further ramify into organized studies and data accumulation. As argued by Thomas S Khun in his book “The Structure of Scientific Revolution” the ‘development-by-accumulation’ model of science is interrupted by episodic accelerations which are sparked by individual observations or thought process [1]. Such observations and deliberations (or anomalies) are, what we can define as the ‘Epitome of Case Reports’.