Validated Spectrophotometric Estimation of Famcoclovir in Tablet Dosage Form.

A simple and sensitive spectrophotometric method has been developed for the estimation of Famciclovir in bulk and tablet dosage form. This was based on the condensation reaction of Famciclovir with carbonyl reagent such as p-dimethylaminocinnamaldehyde (PDCA) in acidic condition to form orange red colored chromogen with absorption maxima at 510 nm. Beer’s law is obeyed in the concentration range of 2-10 mcg/ml. The developed method was validated for precision, accuracy, ruggedness and robustness. Statistical analysis proves that the method is reproducible and selective for the routine analysis of said drug.