Comparative Evaluation of CNS Depressant Activity of the Flavonoid Fractions from the Fresh Leaves and Flowers of Ixora coccinea Linn.

Ixora coccinea Linn belonging to the family Rubiaceae is a plant native to India and Sri Lanka. It is also called Jungle Jeranium. It has been traditionally used in eczema, irregular mensturation, diarrhoea, hypertension skin ulcers, as an antiseptic, antipyretic, anti-inflammatory and anticancer agent. Our present work is the study of its CNS depression activity so that it can be used a herbal sedative The flavonoid fractions of leaves and flowers were tested for CNS depressant activity using Actophotometer where both the leaf and flower extracts showed marked CNS depression up to 87.36%and 95.40%, respectively.