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Hepato-Protective activity of the aqueous extract of launaea intybacea (Jacq) Beauv against carbon tetrachloride-induced hepatic injury in Albino Rats

Keywords: Launaea intybacea , hepatic injury , carbon tetrachloride and silymarin.

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Abstract:

The present study was conducted to evaluate the hepato-protective activity of aqueous extract of aerial parts of launaea intybacea are evaluated in carbon tetrachloride -induced hepatic injury in albino rats. Silymarin (200mg/kg) was given as reference standard. The hepatic injury of CCl 4 and the hepatoprotective effect of aqueous extract of launaea intybacea were estimated their liver function tests. The aqueous extract of aerial parts of launaea intybacea have shown very significant hepatoprotection against carbon tetrachloride -induced hepatic injury in albino rats in reducing serum total bilirubin, SALP, SGPT , SGOT levels and liver homogenates LPO, SOD,CAT, GPX, GST and GSH levels.

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