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Serum Enzymes Levels in HIV/AIDS Patients in Maiduguri, North-Eastern Nigeria

Keywords: AIDS patients , healthy subjects , serum enzyme levels

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Abstract:

The serum enzymes (i.e., Aspartate and Alanine amino transaminases and Alkaline phosphatase) levels in HIV-1 infected symptomatic/AIDS patients in Maiduguri, North- Eastern Nigeria was studied. The sample population used in this study comprised forty AIDS patients and forty healthy subjects as healthy controls. Five milliliter blood sample was collected by aseptic means after obtaining the consent of the patients and subjects. The two groups were screened for HIV. The 40 AIDS patients were confirmed HIV positive and the forty healthy controls were confirmed HIV negative. The serum enzyme levels in both the AIDS patients and the healthy subjects were assessed by serum assays of Aspartate and alanine amino transaminases and alkaline phosphatase. The results show that there is an elevation in serum enzyme levels in HIV/AIDS patients compared to the healthy subjects. This study is aimed at providing information which will help in managing HIV/AIDS patients.

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