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Frequency of Precancerous Lesions in Stomach of Patients

Keywords: Intestinal metaplasia , dysplasia , precancerous lesions

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Abstract:

This descriptive study was done duo to determine of frequencies of precancerous lesions and its significance in gastric cancer prophylaxis and no accessible data about their in this region. From 177 patients with gastrointestinal symptoms that were selected for endoscopy, biopsies were taken from fundus, antrum, lesser curvature. 24.9% of patients had precancerous lesion that 20.9% were Intestinal metaplasia (IM) and 4% of them were dysplasia. Fifty four percent of IM was in antrum, 27.1% in fundus and 18.9% in lesser curvature. In patients with precancerous lesions the most clinical symptom was abdominal pain (29.5%) and the least common was melena (9.1%) and 52.8% of them had Helicobacter pylori (HP) infection. 39.4% of patients were female and 63.3% were male. The most common precancerous lesions were observed in the fourth decade life (29.5%) Therefore considering to high frequency of precancerous lesions in this study and its significance in gastric cancer prophylaxis, serial endoscopic studies are recommended.

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