Preparation and Properties of Supermagnetic?Calcium Phosphate Composite Scaffold

Supermagnetic?calcium phosphate?composite scaffold was fabricated by merging the superparamagnetic iron oxide (SPIO) into the calcium phosphate scaffold, and then sintered in vacuum. Properties of the obtained magnetic scaffold were investigated by SEM, EDS, XRD and VSM. The stability of magnetic scaffold in water was assessed and Ros17/2.8 cells were cultured on the samples to evaluate the cell adhesion on the scaffold. The results demonstrated that the magnetic scaffold had a porous structure. The magnetic nanoparticles were uniformly distributed and firmly merged into the matrix. The content of magnetic nanoparticles could be accurately tuned, and the magnetic scaffold is stable in water. The composite scaffold maintained excellent magnetic properties, as the vacuum sintering procedure avoided the oxidation and phase transition of the magnetic nanoparticles. It is proposed that the magnetic materials might be a kind of potential bone tissue engineering scaffold in the future.