Assembly and Release Behavior of Allopurinol Intercalated Zn/Al―NO3―LDH Composite

Allopurinot intercalated Zn/Al―NO3―LDH composite materials were prepared by coprecipitation and ion exchange methods. It was found by XRD, FT―IR and TG―DTA analysis that allopurinol were intercalated into the LDH layers and formed a supramolecular structure in the reaction with laminate. The structure could improved allopurinol acid resistance and thermal stability. The allopurinol intercalated LDH preparaed by coprecipitation method has an excellent sustained―release performance. It was supposed that the intercalation capacity of organic molecules was increased by a Sol―Gel intermediate which was easy for the objects to be ion―exchanged and embedded during the organic molecules intercalating into the LDH layers by coprecipitation method.