Drosera indica L: Potential effect on liver enzyme, lipid profile and hormone change in DaltonAND#8217;s lymphoma ascites (DLA) bearing mice

Aim: In this study, the ethanol and aqueous extracts of Drosera indica L were prepared and cancer induced liver enzyme, lipid profile and hormone changes were studied in mice using the Dalton’s lymphoma ascites (DLA) cells. Method: Animals were divided into seven groups as the normal control, DLA control, standard (5FU) and the ethanol and aqueous extracts (250 and 500mg/kg each) of D. indica L + DLA (four groups) were given the respective treatments 24 h after tumor cell inoculation, for 14 days. Result: Both ethanol and aqueous extracts of D. indica L at doses of 250 and 500mg/kg extracts showed significant (p<0.001) effects on the elevated liver enzyme, lipid profile and hormonal changes to normal. Conclusion: The results of the present study demonstrated that both extracts were able to normalize the cancer induced liver enzyme, lipid profile and hormone changes in DLA bearing mice. [J Intercult Ethnopharmacol 2012; 1(2.000): 69-73]