Study on Preparation and Properties of Self―setting Silicon HydroxyapatiteBone Cement

Siliconhydroxyapatite cement (s―HAC) was prepared by using the mixed powders oftetracalcium phosphate and dicalcium phosphate anhydrous, and 5wt% sodiumsilicate water solutions as cement liquid. The results show that the settingtime of s―HAC is shorter than hydroxyapatite cement (HAC), and the compressivestrength of s―HAC is higher than HAC in the same situation. The XRD resultsreveal that the finally hardening product of s―HAC is hydroxyapatite structure,which is similar to that of HAC. The s―HAC in the could release calcium (Ca),phosphorus (P) and silicon (Si) ions. The <>in vitro degradability of s―HACin Tris―HCl solution is better than that of HAC. The cell culture experimentalresults indicate that the cell can attach on both the surfaces of s―HAC andHAC, and have good cell morphology. The optical density (OD) and alkalinephosphate (ALP) activity of MG63 cells on s―HAC are significantlyhigher that that of HAC, indicating that the s―HAC could promote the cellproliferation and differentiation.