Case Repert (Polymyositis and Interstitial Lung Disease associated with renal involvement

Polymyositis with interstitial lung disease, renal involvement and positive Anti-Jo-1 antibodies in a 39-year-old male is reported. He presented with cough, dyspnoea and proximal muscle weakness. Chest imaging by X-ray and CT-scan showed wide spread reticulo-nodular densities. Urine analysis revealed RBCs Casts and albumiuria. Open lung biopsy revealed Non-specific interstitial pneumonia and muscle biopsy confirmed the diagnosis of polymyositis. Treating the patient with Prednisolone and Azathioprine showed dramatic improvement.