Extra-Gastrointestinal Stromal Tumor Arising in the Pancreas: A Case Report and Litreature Review

Context Extra-gastrointestinal stromal tumors (EGISTs) of pancreaticorigin are extremely rare entities, of which the prognoses as well asbiological behavioral patterns are yet to be completely unraveled.To our knowledge, only fourteen cases being reported in Englishliterature till date. We intend to present such a case of EGISTs,primarily located in the pancreas, which will most probably be thefifteenth of all the cases to be reported in English medical literature.Apart from presenting this one case we further wish to review andhighlight the salient features, i.e. clinical manifestations, diagnosticparameters, prognoses etc. Case report A fifty-five year old femalepresented with the complaints of pain in the upper abdominal region,with gradual increment in the intensity. The reason for which werefound to be a mass, located in the head of the pancreas, accompaniedby chronic cholecystitis with multiple stones in gall bladder.Contemplating of a pancreatic malignancy, the patient underwent anabdominal laprotomy, during which a rapid intra-operative frozenbiopsy sample was extracted. Further biopsy revealed a malignantgastrointestinal stromal tumour of the pancreatic head. Thus havingarrived at a confirmatory diagnosis, malignant cystic neoplasm of thepancreas, local tumour resection followed by pancreaticojejunostomywith Roux-en-Y anastomosis and cholecyetectomy were executed.Conclusion Despite a being rarity, differential diagnosis of solidand cystic pancreatic masses that could involve the pancreas as theprimary site, without GISTs in view would be a highly imprudentone, particularly owing to the unusually eminent risk of malignancy.The current case consolidates the extra-gastrointestinal stromaltumour of primary pancreatic localization can involve, and should beconsidered in the differential diagnosis of solid and cystic pancreaticmasses.