Some biochemical effects of Aloe vera leaves on tissues in normal mice

This research was carried out mainly to investigate the effects of the aqueous extract and proteinous fractions of Aloe veraleaves on cholesterol, acetycholinesterase in brain, glycogen, glutathione in liver and malonaldehyde levels in heart in normalmale albino mice. The antioxidant properties and inhibition of acetylcholine-sterase in tissue were detected. Intraperitonealadministration of Aloe vera extract in concentration of 400 mg/kg significantly decreased the levels of AchE in brain by (-88.27%) and glutathione content in liver by (-35.48%), and increased the levels of glycogen in liver and malonaldehyde inheart by (22.60%, 85.50%) respectively. At a concentration of 300 mg/kg Aloe vera extract significantly increased the level ofcholesterol in brain by (24.39%). These results clearly show the antioxidant property of the extract of Aloe vera leaves.