A REVIEW ON: PREVENTIVE MAINTENANCE AND TROUBLE SHOOTING OF HPLC

In analytical world HPLC (High Performance Liquid Chromatography) is the more power full tool and it is highly automated and tremendously sensitive. HPLC equipment economically high cost also. In contrast former day’s machinery and instrumentation have improved but typically problems still occur. Especially for in HPLC users but also for advanced learner, need help in separating, identifying and correcting typical problems. Every HPLC system consists of the same basic components, no matter if it is a modular system.Problems can take place in each component and can change the overall performance and also will consume more cost to recover the problems. This review paper provides simple guidelines for maintenance and trouble shooting of HPLC and also solving characteristic and commonly problems in HPLC. An easy-to-use table describes probable cause and solutions.