Extracorporeal photopheresis guidelines GITMO/SIdEM

Despite prophylaxis based on the use of a calcineurin inhibitor in combination with an antimetabolite, acute graft versus host disease (aGvHD) develops in 10-80% of the patients subjected to stem cell transplantation (SCT). Steroids reduce the incidence of aGvHD and, therefore, they represent the most widely employed first-line treatment, which is able to control aGvHDin less than half of the patients...