Studies on Anti-eczema Activity of Esabdamini

Eczema, an inflammatory condition of the skin, is medically treated with the help of topical steroidal creams, avoidance of known allergens, and the administration of immuno-modulators in severe cases. Aim of the present study was to examine the safety of Esabdamini an topical, herbomineral formulation for the relief of mild to moderate eczema. After confirmation of diagnosis, patients meeting the inclusion and exclusion criteria were included in the study and received Esabdamini Ointment to be applied over the affected area/s thrice daily as a thin film and rubbed in gently and completely for 8 weeks. The efficacy was evaluated on the basis of parameters of modified eczema area and the investigator’s global assessment (IGA) on efficacy and tolerability. Esabdamini ointment was well tolerated and did not lead to any abnormalities in the investigations as compared to the baseline values. The investigators global assessment on the eczema treatment showed that 70 % of patients showed a good improvement while another 30% showed fair improvement in their condition by the end of 8 weeks of treatment. Similarly, the patients’ global assessment indicated very good to good response in 50% of the patients at the end of treatment. The efficacy of the developed formulation Esabdamini was found to be very effective without side effects during and after the study and more exploration is required for more effective treatment on large scale. In conclusion, this study confirms the efficacy and safety of Esabdamini Ointment in mild to moderate eczema patients.