SYNERGISTIC EFFET OF INDIGENOUS MEDICINAL PLANT EXTRACTS ON PSORIASIS

The present paper deals with evaluation of synergistic effect of two medicinal plants, Ponamia pinnata Linn and Psoralea corylifolia Linn. Extraction was carried out with soxhlet apparatus using the solvent ethanol. The anti-psoriatic activity was done by Induction of psoriasiform changes in guinea pig by propranolol method and Rat UV B rays Photo dermatitis model for psoriasis. Antimicrobial activity by plate hole diffusion method. Ethanolic extract exhibited significant effect of anti-psoriatic and antimicrobial activity. Both the extracts show synergistic effect on both psoriasis and antimicrobial studies when compared with the individual extracts.