SIMPLE QUANTITATIVE METHOD DEVELOPMENT AND VALIDATION OF VALSARTAN IN PURE FORM AND PHARMACEUTICAL DOSAGE FORMS BY UV-SPECTROSCOPY

Simple precise accurate UV Spectroscopic method has been developed and validated for estimation of valsartan in pure and pharmaceutical dosage form. UV Spectroscopic method which is based on measurement of absorption of UV light, the spectra of valsartan in methanol showed maximum wave length at 250nm and calibration graphs were plotted over the concentrations ranging from 2-20μg/ml of valsartan with correlation coefficient 0.9968 validation was performed as per ICH Q2 (R1) guidelines for linearity, accuracy, precision and recovery. The limit of detection (LOD) and limit of quantification (LOQ) were found to be 0.15 and 0.449 respectively by simple UV Spectroscopy .The proposed method was validated.